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PLA2G4D

  • Official Full Name

    phospholipase A2, group IVD (cytosolic)

  • Overview

    The phospholipase A2 enzyme family, including PLA2G4D, catalyze the hydrolysis of glycerophospholipids at the sn-2;position and then liberate free fatty acids and lysophospholipids (Chiba et al., 2004 (PubMed 14709560)).
  • Synonyms

    PLA2G4D; phospholipase A2, group IVD (cytosolic); cytosolic phospholipase A2 delta; cPLA2delta; cPLA2 delta; Phospholipase A2 group IVD; cPLA2-delta; phospholipase A2 delta, cytosolic;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PLA2G4D-1754H Recombinant Human PLA2G4D, GST-tagged E.coli GST 1-216aa
Human PLA2G4D-1368HCL Recombinant Human PLA2G4D cell lysate N/A
Human PLA2G4D-1421H Recombinant Human PLA2G4D protein, His & GST-tagged E.coli His/GST Pro9~Leu120 (Accession # Q86XP0)
Human PLA2G4D-1695H Recombinant Human PLA2G4D Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PLA2G4D-1695H-B Recombinant Human PLA2G4D Protein Pre-coupled Magnetic Beads HEK293
Human PLA2G4D-1876H Recombinant Human PLA2G4D Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human PLA2G4D-1926HFL Recombinant Full Length Human PLA2G4D Protein, C-Flag-tagged Mammalian cells Flag
Mouse PLA2G4D-12897M Recombinant Mouse PLA2G4D Protein Mammalian Cell His
Mouse PLA2G4D-6800M-B Recombinant Mouse PLA2G4D Protein Pre-coupled Magnetic Beads HEK293
Mouse PLA2G4D-6800M Recombinant Mouse PLA2G4D Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Pla2g4d-4902M Recombinant Mouse Pla2g4d Protein, Myc/DDK-tagged HEK293T Myc/DDK
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PLA2G4D involved in several pathways and played different roles in them. We selected most pathways PLA2G4D participated on our site, such as Glycerophospholipid metabolism, Ether lipid metabolism, Arachidonic acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLA2G4D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycerophospholipid metabolismAGPAT4;PLA2G16;PLA2G12B;PLA2G15;TAZ;MBOAT2;DGKZ;PISD;TAE1
Ether lipid metabolismEPT1;CEPT1B;PAFAH1B2;PLA2G4D;PPAP2C;PAFAH2;PLA2G2F;PLA2G4B;PLA2G4F
Arachidonic acid metabolismCYP2P10;CYP2B6;CYP2C8;ALOX5A;CYP2B19;GPX8;MAPKAPK2B;GPX6;GPX3
Linoleic acid metabolismCYP2C38;PLA2G2E;CYP3A41B;PLA2G5;CYP2C37;PLA2G4A;PLA2G4F;PLA2G4AA;CYP2C50
alpha-Linolenic acid metabolismPLA2G3;ACAA1;ACAA1A;ACOX3;PLA2G12B;PLA2G2D;PLA2G4D;FADS2;PLA2G6
Metabolic pathwaysTYRP1B;PYGL;PCCA;AOC3;ATP5O;ALDOAA;NT5C1BA;PNLIP;DPM3
MAPK signaling pathwayNF1;FGF1B;FGF13;NFATC1;CACNB4A;CASP3A;MAX;CACNA1C;MAPK4
Ras signaling pathwayPLCE1;FGF2;LAT;FGF6;FGF21;KSR2;FGF13;FASLG;FGF18
Phospholipase D signaling pathwayPTPN11;PIK3CB;SHC2;AGPAT3;AGPAT4;SYK;CXCR1;PIK3R2;INS2
Vascular smooth muscle contractionPLA2G2E;ITPR1;CYP4A12A;ACTA2;PRKCD;PRKCDA;KCNMB4;GNA12A;PPP1CAA
VEGF signaling pathwayBAD;PLA2G4C;SH2D2A;PTK2;PIK3R5;PTK2AB;VEGFA;PRKCG;PXNA
Platelet activationAKT2;P2RY12;ITPR3;PLCB3;RHOA;FERMT3;GUCY1A3;MAPK13;MYLK4
Fc epsilon RI signaling pathwayPIK3R1;FYN;MAPK3;AKT1;MAPK11;GM-CSF;VAV1;MAP2K4;GRB2
Fc gamma R-mediated phagocytosisPLA2G4D;PRKCB;VAV1;WASF2;ASAP2;PIK3R2;ARF6;PLD2;PLD1
Glutamatergic synapsePPP3R1;PLD1;PRKCA;PLD2;MAPK3;SHANK1;GRM4;Adcy4;GNAI3
Serotonergic synapsePRKACB;PTGS2;CYP2D10;Casp3;HTR2A;GNAQ;CYP4X1;CYP2C37;HTR3C
Long-term depressionGNAS;ITPR1;GRM1;PPP1R17;PLCB3;PLA2G4F;GRID2;IGF1R;PRKCA
Inflammatory mediator regulation of TRP channelsPPP1CB;CAMK2D;CALML3;PPP1CC;NGF;CAMK2G;TRPM8;MAPK13;PIK3R1
GnRH signaling pathwayGNRH3;GNRH2;ITPR1;HRASA;PRKACBB;CDC42L2;GNRHR;MAP3K4;ADCY1A
Ovarian steroidogenesisALOX5;GDF9;AKR1C3;PLA2G4F;CYP2J6;PRKACA;ACOT2;IGF1R;FSHB
Oxytocin signaling pathwayPRKCB;KCNJ14;PPP1R12B;NFATC3;GUCY1A3;CALML5;NFATC2;MYL6B;MYL9
Choline metabolism in cancerPRKCA;PRKCG;PPAP2B;RAC3;RAC1;WASF3;PRKCB;SLC22A5;DGKQ

PLA2G4D has several biochemical functions, for example, metal ion binding, phospholipase A2 activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PLA2G4D itself. We selected most functions PLA2G4D had, and list some proteins which have the same functions with PLA2G4D. You can find most of the proteins on our site.

Function Related Protein
metal ion bindingGUCA1D;ZNF598;ZFP74;TAE1;CYP4A10;KDM8;VEPH1;ZBTB22;DPH3P1
phospholipase A2 activityLCAT;PLA2G4AA;RARRES3;OC90;PLA2G4A;PLA2G1B;PNPLA3;PLA2G2E;PLA2G2F

PLA2G4D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLA2G4D here. Most of them are supplied by our site. Hope this information will be useful for your research of PLA2G4D.

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