plin2
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  • Official Full Name
  • perilipin 2
  • Background
  • The protein encoded by this gene belongs to the perilipin family, members of which coat intracellular lipid storage droplets. This protein is associated with the lipid globule surface membrane material, and maybe involved in development and maintenance of adipose tissue. However, it is not restricted to adipocytes as previously thought, but is found in a wide range of cultured cell lines, including fibroblasts, endothelial and epithelial cells, and tissues, such as lactating mammary gland, adrenal cortex, Sertoli and Leydig cells, and hepatocytes in alcoholic liver cirrhosis, suggesting that it may serve as a marker of lipid accumulation in diverse cell types and diseases. Alternatively spliced transcript variants have been found for this gene.
  • Synonyms
  • PLIN2; perilipin 2; ADFP; ADRP; adipose differentiation-related protein; adipophilin; Perilipin-2; Adipophilin; Adipose differentiation-related protein; perilipin-2; MGC1059; OTTHUMP00000021107
Cat.#:ADRP-3201HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PLIN2 protein, His-tagged
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Cat.#:ADRP-3207HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PLIN2 protein, His-tagged
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Cat.#:PLIN2-201HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PLIN2, T7 tagged
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Cat.#:PLIN2-341HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human PLIN2 Protein, GST-tagged
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Cat.#:PLIN2-62HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Perilipin 2, T7-tagged
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Cat.#:PLIN2-63HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PLIN2, His-tagged
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Cat.#:PLIN2-904HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Perilipin 2, His-tagged
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Cat.#:PLIN2-9448HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PLIN2, His-tagged
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Cat.#:PLIN2-12972MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PLIN2 Protein
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Cat.#:PLIN2-3070CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PLIN2
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Cat.#:PLIN2-3342ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PLIN2
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Cat.#:PLIN2-3107HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PLIN2 293 Cell Lysate
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Involved Pathway

PLIN2 involved in several pathways and played different roles in them. We selected most pathways PLIN2 participated on our site, such as Adipogenesis, Fatty acid, triacylglycerol, and ketone body metabolism, HIF-1-alpha transcription factor network, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLIN2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adipogenesis
RORAA; MEF2B; CYP26A1; PIANP; PLIN2; CDKN1A; BMP1; KLF7; DDIT3; GTF3AA
Fatty acid, triacylglycerol, and ketone body metabolism
MED6; MMAA; MED16; Agmo; MED8; HELZ2; ACOT2; SREBF2; CCNC; SIN3B
HIF-1-alpha transcription factor network
GATA2; ENG; NDRG1; TFF3; NPM1; EGLN3; COPS5; PLIN2; CITED2; ADM
Metabolism
ACOT13; ABHD14B; APOBB.1; ACOT12; AZIN1A; ALDH9A1A.2; MED18; FAAH2A; SLC25A32A; B3GAT2
Metabolism of lipids and lipoproteins
CYP2AD2; CYP2N13; GC; ACOT7; SLC44A5B; GRHL1; CHAT; ARSF; MED19; SPTLC1
PPARA activates gene expression
MED18; CDK19; SREBF2; MED9; APOA5; PLIN2; MED29; MED10; MED21; MED20
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
MED22; MED10; MED6; PLIN2; MTF1; GRHL1; MED9; MED21; MED20; MED25

Interacting Protein

PLIN2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLIN2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLIN2.
MAPK10; ftsX

PLIN2 Related Articles

Kimura, A; Sakurai, T; et al. Identification of Target Antigens of Antiendothelial Cell Antibodies Against Human Brain Microvascular Endothelial Cells in Healthy Subjects. CURRENT NEUROVASCULAR RESEARCH 12:25-30(2015).
Mulay, K; White, VA; et al. Sebaceous carcinoma: clinicopathologic features and diagnostic role of immunohistochemistry (including androgen receptor). CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE 49:326-332(2014).