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  • Official Full Name
  • polymerase (DNA directed), lambda
  • Background
  • This gene encodes a DNA polymerase. DNA polymerases catalyze DNA-template-directed extension of the 3-end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymerases, likely plays a role in non-homologous end joining and other DNA repair processes. Alternatively spliced transcript variants have been described.
  • Synonyms
  • POLL; polymerase (DNA directed), lambda; DNA polymerase lambda; BETA N; BETAN; DNA directed DNA polymerase lambda; DNA polymerase beta 2; DNA polymerase beta-2; DNA polymerase kappa; DNA polymerase kappa DNA polymerase beta N; DNA polymerase lamda2; DPOLL_HUMAN; EC 2.7.7.7,EC 4.2.99.; FLJ46002; OTTHUMP00000020321; OTTHUMP00000020323; OTTHUMP00000059179; Pol beta2; POL KAPPA; Pol Lambda; POLKAPPA; Polymerase DNA directed lambda; DNA polymerase beta-N
Cat.#:POLL-1205HTag:Myc|DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human POLL Protein, MYC/DDK-tagged
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Cat.#:POLL-1206HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human POLL Protein, GST-tagged
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Cat.#:POLL-1528HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human POLL protein
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Cat.#:POLL-28363THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human POLL, His-tagged
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Cat.#:POLL-621HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Polymerase (DNA Directed), Lambda
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Cat.#:POLL-6891HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Polymerase (DNA directed), Lambda, His-tagged
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Cat.#:POLL-13083MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse POLL Protein
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Cat.#:POLL-4566RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat POLL Protein
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Cat.#:POLL-800CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus POLL Protein, His-tagged
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Cat.#:POLL-3510RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey POLL Protein, His-tagged
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Cat.#:POLL-12445ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish POLL
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Cat.#:POLL-3044HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human POLL 293 Cell Lysate
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Involved Pathway

POLL involved in several pathways and played different roles in them. We selected most pathways POLL participated on our site, such as Base excision repair, Non-homologous end-joining, which may be useful for your reference. Also, other proteins which involved in the same pathway with POLL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Base excision repair
mutY; UNG; POLD2; TDG.1; APEX2; POLE; HMGB1; POLD1; PNKP; PARP1
Non-homologous end-joining
MRE11A; DCLRE1C; NHEJ1; DNTT; PRKDC; XRCC6; XRCC4; FEN1; POLL; POLM

Protein Function

POLL has several biochemical functions, for example, DNA binding, DNA-directed DNA polymerase activity, lyase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by POLL itself. We selected most functions POLL had, and list some proteins which have the same functions with POLL. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein PMS1; DDX3Y; ZBED5; EGR4; SIM1B; ZNF35; NR1H5; RYBPA; HMGB1A; RUNX2A
Function DNA-directed DNA polymerase activity
Related Protein POLE; POLN; POLL; MYBBP1A; POLM; POLD3; POLE4; POLD1; POLA1; PRIMPOL
Function lyase activity
Related Protein TYW1B; ENO1A; ALDOCA; GUCY2F; TYW1; ADCY1B; ETNPPL; AMD2; NPR1A; TSEN2
Function metal ion binding
Related Protein ITPA; ARAP2; ZFP57; NEK1; HAND2; ASPA; KLF1; AMY1B; CYP2C55; USP2
Function protein binding
Related Protein SRMS; ZNF286A; TSSK6; AEBP2; ZBED3; SSB; FOXC1; PMF1; TDRKH; ZNF217

Interacting Protein

POLL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POLL here. Most of them are supplied by our site. Hope this information will be useful for your research of POLL.
UBC; XRCC1; LDOC1

POLL Related Articles

Salmanzadeh, M; Saeedi, M; et al. Characterization and metals fractionation of street dust samples from Tehran, Iran. INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH 9:213-224(2015).
Gerstenfeld, M; et al. The Run-Up to Israel's 2013 Elections: A Political History. ISRAEL AFFAIRS 21:177-194(2015).