ppip5k2
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  • Official Full Name
  • diphosphoinositol pentakisphosphate kinase 2
  • Background
  • Inositol phosphates (IPs) and diphosphoinositol phosphates (PP-IPs), also known as inositol pyrophosphates, act as cell;signaling molecules. HISPPD1 has both IP6 kinase (EC 2.7.4.21) and PP-IP5 (also called IP7) kinase (EC 2.7.4.24);activities that produce the high-energy pyrophosphates PP-IP5 and PP2-IP4 (also called IP8), respectively (Fridy et;al., 2007 (PubMed 17690096)).
  • Synonyms
  • PPIP5K2; diphosphoinositol pentakisphosphate kinase 2; HISPPD1, histidine acid phosphatase domain containing 1; inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2; KIAA0433; VIP2; hsVIP2; VIP1 homolog 2; insP6 and PP-IP5 kinase 2
Cat.#:PPIP5K2-2671HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPIP5K2 Protein, His-tagged
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Cat.#:PPIP5K2-13193MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PPIP5K2 Protein
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Involved Pathway

PPIP5K2 involved in several pathways and played different roles in them. We selected most pathways PPIP5K2 participated on our site, such as Phosphatidylinositol signaling system, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPIP5K2 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Phosphatidylinositol signaling system
TMEM55B; DGKE; OCRL; INPP5D; INPP5K; INPP5KA; PLCD3A; ITPK1A; PIP5K1BA; IP6K2

Protein Function

PPIP5K2 has several biochemical functions, for example, ATP binding, acid phosphatase activity, diphosphoinositol-pentakisphosphate kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPIP5K2 itself. We selected most functions PPIP5K2 had, and list some proteins which have the same functions with PPIP5K2. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein CHD9; MAPK8; ATP1A4; STYK1; GLYCTK; NLRP4; FGFR3; ERBB3B; MAP3K12; CSNK1A1L
Function acid phosphatase activity
Related Protein ACPT; PXYLP1; ACP2; MINPP1A; PPIP5K1; MINPP1; ACP5A; MINPP1B; PPIP5K2; ACP1
Function diphosphoinositol-pentakisphosphate kinase activity
Related Protein PPIP5K1; PPIP5K2
Function inositol hexakisphosphate 1-kinase activity
Related Protein IP6K3; IP6K2; PPIP5K2; IP6K1; PPIP5K1
Function inositol hexakisphosphate 3-kinase activity
Related Protein PPIP5K1; IP6K1; IP6K2; IP6K3; PPIP5K2
Function inositol hexakisphosphate 5-kinase activity
Related Protein PPIP5K2; IP6K3; PPIP5K1; IP6K1; IP6K2
Function inositol hexakisphosphate kinase activity
Related Protein PPIP5K2
Function kinase activity
Related Protein GRK1B; VPRBP; MAP2K4A; PDXKB; DNAJC3B; AKT1; PI4KAA; RPS6KB1B; CKMT2B; DGKAA
Function nucleotide binding
Related Protein IIGP1; EIF3BA; RBM14A; PPARGC1B; GNA12A; HNRNPD; SAR1AB; Akap17b; SLTM; MSI2B
Function transferase activity
Related Protein DNAJC3B; UGT1A6A; COQ2; SULT6B1; RAF1A; PRKACAB; PTAR1; UGT2B3; VPRBP; MKNK2B

PPIP5K2 Related Articles

Williams, SP; Gillaspy, GE; et al. Biosynthesis and possible functions of inositol pyrophosphates in plants. FRONTIERS IN PLANT SCIENCE 6:-(2015).
Capolicchio, S; Wang, HC; et al. Synthesis of Densely Phosphorylated Bis-1,5-Diphospho-myo-Inositol Tetrakisphosphate and its Enantiomer by Bidirectional P-Anhydride Formation. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 53:9508-9511(2014).