ppm1k
Share
  • Official Full Name
  • protein phosphatase, Mg2+/Mn2+ dependent, 1K
  • Background
  • Protein phosphatase 1K, mitochondrial is an enzyme that in humans is encoded by the PPM1K gene.
  • Synonyms
  • PPM1K; protein phosphatase, Mg2+/Mn2+ dependent, 1K; protein phosphatase 1K (PP2C domain containing); protein phosphatase 1K, mitochondrial; DKFZp761G058; hPTMP; PP2C type mitochondrial phosphoprotein phosphatase; PP2Ckappa; PP2Cm; protein phosphatase 2C kappa; PP2C domain containing protein phosphatase 1K; PP2C kappa; PP2C like mitochondrial protein; Protein phosphatase 2C isoform kappa; PTMP; PP2C-kappa; PP2C-like protein; PP2C-like mitochondrial protein; PP2C type mitochondrial phosphatase; PP2C domain-containing protein phosphatase 1K; PP2C-type mitochondrial phosphoprotein phosphatase; UG0882E07
Cat.#:PPM1K-174HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human PPM1K, His-tagged
+Inquiry
Cat.#:PPM1K-3555RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PPM1K Protein, His-tagged
+Inquiry
Cat.#:PPM1K-2103ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PPM1K
+Inquiry
Cat.#:PPM1K-2957HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human PPM1K 293 Cell Lysate
+Inquiry

Involved Pathway

PPM1K involved in several pathways and played different roles in them. We selected most pathways PPM1K participated on our site, such as Branched-chain amino acid catabolism, Metabolism, Metabolism of amino acids and derivatives, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPM1K were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Branched-chain amino acid catabolism
BCKDK; ALDH9A1A.2; IVD; HIBADH; PPM1K; DLD; HIBADHA; DBT
Metabolism
DCT; GCKR; CTRC; APOA4B.1; B4GALT7; ADSL; HAS1; Sult2a2; UGT1B3; LOC100686744
Metabolism of amino acids and derivatives
BHMT2; SLC25A21; CKB; CKM; SLC25A15B; DAO; AFMID; SLC6A8; SLC6A7; CKMT1B

Protein Function

PPM1K has several biochemical functions, for example, metal ion binding, protein binding, protein serine/threonine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPM1K itself. We selected most functions PPM1K had, and list some proteins which have the same functions with PPM1K. You can find most of the proteins on our site.
Function
Related Protein
Function metal ion binding
Related Protein GUCA1B; ZMYND19; ZFP146; ATP2B4; BMPR1A; ZFP770; CDC7; ZFP41; BMI1B; EXT1B
Function protein binding
Related Protein Reln; GATAD2B; ESR2; C10orf35; DNAJA3; HMG20B; YES1; USP46; TNFAIP8L1; DAZAP2
Function protein serine/threonine phosphatase activity
Related Protein PPM1K; PPP1CC; PPP2R1A; PDP2; CDC14AA; PPM1AA; DUSP23B; PTEN; PPP2R2A; PPM1BA

Interacting Protein

PPM1K has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPM1K here. Most of them are supplied by our site. Hope this information will be useful for your research of PPM1K.
BIRC2; MYB

PPM1K Related Articles

Lynch, CJ; Adams, SH; et al. Branched-chain amino acids in metabolic signalling and insulin resistance. NATURE REVIEWS ENDOCRINOLOGY 10:723-736(2014).
Chan, WL; Yuo, CY; et al. Transcribed pseudogene psi PPM1K generates endogenous siRNA to suppress oncogenic cell growth in hepatocellular carcinoma. NUCLEIC ACIDS RESEARCH 41:3734-3747(2013).