PPM1L
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Official Full Name
protein phosphatase, Mg2+/Mn2+ dependent, 1L
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Overview
PPM1L, or PP2CE, belongs to the PP2C group of serine/threonine phosphatases, which are distinguished from other;phosphatases by their structure, absolute requirement for Mg(2+) or Mn(2+), and insensitivity to okadaic acid. PP2Cs;regulate stress-activated protein kinase (SAPK; see MIM 601158) signaling cascades that respond to extracellular;stimuli (Jin et al., 2004 (PubMed 15560375)). -
Synonyms
PPM1L; protein phosphatase, Mg2+/Mn2+ dependent, 1L; protein phosphatase 1 (formerly 2C) like; protein phosphatase 1L; PP2CE; PP2Cepsilon; Protein phosphatase 2C epsilon isoform; PP2C epsilon; protein phosphatase 2C isoform epsilon; PPM1-LIKE; PP2C-epsilo;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Bos taurus (Bovine)
- Human
- Mouse
- E.coli
- E.coli expression system
- HEK293
- HEK293T
- Mammalian Cell
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | PPM1L-80H | Recombinant Human PPM1L protein, His-tagged | E.coli | His | 196aa(including fusion tag) |
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| Human | PPM1L-2956HCL | Recombinant Human PPM1L 293 Cell Lysate | HEK293 | N/A |
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| Mouse | PPM1L-13204M | Recombinant Mouse PPM1L Protein | Mammalian Cell | His |
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| Mouse | Ppm1l-5052M | Recombinant Mouse Ppm1l Protein, Myc/DDK-tagged | HEK293T | Myc/DDK |
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| Mouse | PPM1L-6995M-B | Recombinant Mouse PPM1L Protein Pre-coupled Magnetic Beads | HEK293 |
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| Mouse | PPM1L-6995M | Recombinant Mouse PPM1L Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
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| Bos taurus (Bovine) | RFL18794BF | Recombinant Full Length Bovine Protein Phosphatase 1L(Ppm1L) Protein, His-Tagged | E.coli expression system | His | Full Length (1-360) |
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- Involved Pathway
- Protein Function
- Interacting Protein
- PPM1L Related Research Area
PPM1L involved in several pathways and played different roles in them. We selected most pathways PPM1L participated on our site, such as Metabolism, Metabolism of lipids and lipoproteins, Sphingolipid de novo biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPM1L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism | CYP2A7;PDK2B;COX5B;SLC2A3;AZIN1;ABHD4;TACO1;NFYBB;ACSM1 |
| Metabolism of lipids and lipoproteins | SACM1L;LBR;AWAT2;FABP11B;FABP9;MTP;ACAD11;FAAH2;MED18 |
| Sphingolipid de novo biosynthesis | FA2H;GDF1;CERS5;SPTLC1;CERS3B;PPM1L;PPM1LB;VAPB;OSBP |
| Sphingolipid metabolism | NEU1;DEGS2;NEU3.1;CERS1;DEGS1;SGPP2;SGMS1;VAPB;ARSE |
PPM1L has several biochemical functions, for example, metal ion binding, protein serine/threonine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPM1L itself. We selected most functions PPM1L had, and list some proteins which have the same functions with PPM1L. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| metal ion binding | RAB11FIP4A;ZKSCAN6;SMG1;SMAP1;ALOX5B.3;PRDM8B;NKD2B;ZFP428;AGAP5 |
| protein serine/threonine phosphatase activity | PPM1DB;PPM1LA;PPM1F;PPP5C;PTEN;CDC14B;DUSP23;PPM1L;PPM1BB |
PPM1L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPM1L here. Most of them are supplied by our site. Hope this information will be useful for your research of PPM1L.
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