"PPM1L" Related Products

Recombinant Human PPM1L protein, His-tagged

Cat.No.: PPM1L-80H
Product Overview: Recombinant Human PPM1L, fused with N-His tag, was expressed in E. coli.
Description: PPM1L, or PP2CE, belongs to the PP2C group of serine/threonine phosphatases, which are distinguished from other phosphatases by their structure, absolute requirement for Mg(2+) or Mn(2+), and insensitivity to okadaic acid. PP2C sregulate stress-activated protein kinase (SAPK; see MIM 601158) signaling cascades that respond to extra cellularstimuli.
Source: E.coli
Species: Human
Tag: His
Form: 20mM Tris.Cl, 50mM NaCl, 50% Glycerol, pH8.0.
Molecular Mass: 22.2kDa(including fusion tag)
Protein length: 196aa(including fusion tag)
Applications: WB, ELISA, IP, antibody production, protein array
Storage: Store at -80centigrade and avoid repeated freeze-thaw cycles.
Gene Name: PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L [ Homo sapiens ]
Official Symbol: PPM1L
Synonyms: PPM1L; protein phosphatase, Mg2+/Mn2+ dependent, 1L; protein phosphatase 1 (formerly 2C) like; protein phosphatase 1L; PP2CE; PP2Cepsilon; Protein phosphatase 2C epsilon isoform; PP2C epsilon; protein phosphatase 2C isoform epsilon; PPM1-LIKE; PP2C-epsilon; MGC132545; MGC132547;
Gene ID: 151742
mRNA Refseq: NM_139245
Protein Refseq: NP_640338
MIM: 611931
UniProt ID: Q5SGD2
Chromosome Location: 3q26.1
Pathway: Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Sphingolipid de novo biosynthesis, organism-specific biosystem; Sphingolipid metabolism, organism-specific biosystem;
Function: hydrolase activity; metal ion binding; protein serine/threonine phosphatase activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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