PPP1R13L Protein, protein phosphatase 1, regulatory subunit 13 like


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Official Full Name protein phosphatase 1, regulatory subunit 13 like
Background IASPP is one of the most evolutionarily conserved inhibitors of p53 (TP53; MIM 191170), whereas ASPP1 (MIM 606455) and ASPP2 (MIM 602143) are activators of p53.
Synonyms PPP1R13L; protein phosphatase 1, regulatory subunit 13 like; protein phosphatase 1, regulatory (inhibitor) subunit 13 like; relA-associated inhibitor; IASPP; RAI; protein iASPP; PPP1R13B-like protein; retinoic acid induced 4; inhibitor of ASPP protein; NF
    • Species :
    • Human
    • Zebrafish
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PPP1R13L-1399HCL Recombinant Human PPP1R13L cell lysate N/A
    Human PPP1R13L-1903H Recombinant Human PPP1R13L, His-tagged E.coli His
    Zebrafish PPP1R13L-2249Z Recombinant Zebrafish PPP1R13L Mammalian Cell His

    PPP1R13L involved in several pathways and played different roles in them. We selected most pathways PPP1R13L participated on our site, such as Integrated Pancreatic Cancer Pathway, TNF-alpha/NF-kB Signaling Pathway, p53 pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP1R13L were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Integrated Pancreatic Cancer Pathway RB1CC1; CASP12; GPRC5A; TOP2A; CD82; MAPK4; TFF1; TOP1; FST; BRF1
    TNF-alpha/NF-kB Signaling Pathway G3BP2; NR2C2; SMARCE1; NKIRAS2; PDCD2; MARK2; USP2; KIAA1967; TRAIP; DDX3X
    p53 pathway CSNK1G3; TTC5; SMYD2; RASSF1; E4F1; KAT8; TRIM28; CSE1L; NEDD8; DYRK2

    PPP1R13L has several biochemical functions, for example, identical protein binding, protein binding, transcription corepressor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP1R13L itself. We selected most functions PPP1R13L had, and list some proteins which have the same functions with PPP1R13L. You can find most of the proteins on our site.

    Function Related Protein
    identical protein binding MCM6; EGFR; FHIT; ESYT2; SDCBP; BCL2; CRYAB; LEPR; ESR1; SQSTM1
    protein binding AEBP2; PLAA; ZC3H11A; TUBA3D; CTR9; KRTAP10-7; C9orf86; STEAP3; ZNF397; KLHDC4
    transcription corepressor activity NFKBIL2; ATF7IP; NRIP1; CTBP2A; SAP18; LOXL2; JAZF1; SUFU; TBL1X; APEX1
    transcription factor binding HEY2; HDAC5; NR0B1; NFYC; RNF19A; PITX2; IFT172; TRAPPC2; PAX6; NKX3-1

    PPP1R13L has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP1R13L here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP1R13L.

    TP53; PPP1CA; RAN

    Notari, M; Hu, Y; et al. iASPP, a previously unidentified regulator of desmosomes, prevents arrhythmogenic right ventricular cardiomyopathy (ARVC)-induced sudden death. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 112:E973-E981(2015).
    Offenmuller, S; Ravindranath, Y; et al. Focused screening of a panel of cancer-related genetic polymorphisms reveals new susceptibility loci for pediatric acute lymphoblastic leukemia. PEDIATRIC BLOOD & CANCER 61:1411-1415(2014).

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