Ppp2r2a

  • Official Full Name

    protein phosphatase 2, regulatory subunit B, alpha

Recombinant Proteins

  • Mouse
  • Chicken
  • Rat
  • Cynomolgus
  • Human
  • Mammalian Cells
  • HEK293
  • E.coli
  • His
  • Non
  • Avi
  • Fc

    Involved Pathway

    Ppp2r2a involved in several pathways and played different roles in them. We selected most pathways Ppp2r2a participated on our site, such as mRNA surveillance pathway,Sphingolipid signaling pathway,PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ppp2r2a were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    PIK-Akt signaling pathway PPP2R5E,FGF9,PRKAA2,IFNA8,PPP2R5C,FGF11,HGF,PCK2,Il4ra,SGK3
    Hippo signaling pathway TEAD1,FZD3,WNT2,SMAD1,GDF5,GDF7,GDF6,BMP6,WNT5A,CTGF
    Sphingolipid signaling pathway SGPP2,MAP2K1,SMPD1,MAPK10,PPP2R5A,PRKCZ,SGPL1,RAC3,PPP2R5E,SGMS2
    Adrenergic signaling in cardiomyocytes CALM4,SCN1B,CACNA2D4,MYH15,PPP2R2B,CALM,PLCB2,PPP2R2BB,PPP1CB,ADCY1
    Dopaminergic synapse GRIA4,GNAS,PLCB2,GNGT2,KCNJ5,PRKACB,AKT1,ITPR3,PPP3CB,GNB3
    Hepatitis C CLDN22,IL-8,SCARB1,IKBKE,IRF1,CLDN17,PPARA,DDX58,CLDN16,MAPK1
    Tight junction MLLT4,ACTN3B,CLDN5B,MYH6,JAM2,CLDN9,VAPAL,EPB41L3,VMHCL,MYH1B
    AMPK signaling pathway HMGCR,PFKFB2,PPP2R2C,PPP2R3C,PFKM,PPARGC1A,HNF4A,FOXO1,CPT1A,PPP2R5C
    Chagas disease (American trypanosomiasis) CCL3L1,IL12B,PIK3CG,MAPK12,CASP8,MYD88,IL-8,GNAI1,PLCB3,PPP2CA

    Protein Function

    Ppp2r2a has several biochemical functions, for example, protein binding,protein complex binding,protein phosphatase 2A binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Ppp2r2a itself. We selected most functions Ppp2r2a had, and list some proteins which have the same functions with Ppp2r2a. You can find most of the proteins on our site.

    Function Related Protein
    protein phosphatase 2A binding CPD,MAPT,STRN,PPP2R4,TP53,FOXO1,ANKLE2,PTPN1,IGBP1,MASTL
    protein binding RPL10,TMEM19,MOB1A,TMPRSS15,TSSC4,DCUN1D5,NOMO2,C1orf38,CHGB,BSG
    protein serine/threonine phosphatase activity CTDNEP1A,PPP3CB,CDC14C,UBLCP1,PPM1K,PDP2,MTMR6,PPM1H,PPM1G,PPM1NB
    protein complex binding CTSL2,PTK2B,PDZK1,WRN,ITGB1BP1,TUBB,MTHFR,PDCL,LZTFL1,RXRA
    tau protein binding APOE,HDAC6,SERPINB1A,DYRK1A,FKBP4,BIN1,AATF,S100B,SNCA
    protein phosphatase type 2A regulator activity EIF2AK2,pab1,PPP2R2D,PPP2R2B,PPP2R4,PPP2R2BB,PPP2R5B,PPP2R1A,ENSAA,IGBP1

    Interacting Protein

    Ppp2r2a has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ppp2r2a here. Most of them are supplied by our site. Hope this information will be useful for your research of Ppp2r2a.

    PPP2R1A;PPP2CA;PPP2CB;PPP2R1B

    Resources

    References

    • Kurimchak, A; Grana, X; et al. PP2A: more than a reset switch to activate pRB proteins during the cell cycle and in response to signaling cues. CELL CYCLE 14:18-30(2015).
    • Zhang, DB; Wang, J; et al. miR-136 Modulates TGF-beta 1-Induced Proliferation Arrest by Targeting PPP2R2A in Keratinocytes. Biomed Research International :-(2015).

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