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Recombinant Cynomolgus PPP2R2A Protein, His-tagged

Cat.No. : PPP2R2A-807C
Product Overview : Recombinant Cynomolgus PPP2R2A full length or partial length protein was expressed.
  • Specification
  • Gene Information
  • Related Products
Source : Mammalian Cells
Species : Cynomolgus
Tag : His
Form : Liquid or lyophilized powder
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method.
Purity : >80%
Notes : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Storage : Store it at +4 ºC for short term. For long term storage, store it at -20 ºC~-80 ºC.
Storage Buffer : PBS buffer
Gene Name : PPP2R2A Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform [ Macaca fascicularis (crab-eating macaque) ]
Official Symbol : PPP2R2A
Synonyms : PPP2R2A; PP2A subunit B isoform B55-alpha; PP2A subunit B isoform PR55-alpha; PP2A subunit B isoform R2-alpha; PP2A subunit B isoform alpha;
Gene ID : 101926197
mRNA Refseq : NM_001283453
Protein Refseq : NP_001270382
MIM :
UniProt ID : Q4R7Z4

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What changes were observed in GFPT2 phosphorylation levels after downregulating PPP2R2A? 08/31/2022

Following the downregulation of PPP2R2A using shRNA, a significant increase in GFPT2 phosphorylation levels was observed, while the phosphorylation levels of GFPT1 did not show significant changes.

What methods were employed in this study to screen PPP2R2A interaction proteins? 06/10/2021

The study used tandem affinity purification combined with HPLC-Chip-ESI/MS/MS to screen for proteins interacting with PPP2R2A.

Which proteins were identified as potential binding partners of PPP2R2A in this study? 08/29/2019

The analysis revealed that Glutamine-fructose-6-phosphate transaminase 1 (GFPT1) and Glutamine-fructose-6-phosphate transaminase 2 (GFPT2) are potential binding partners of PPP2R2A.

How was the interaction between PPP2R2A and GFPT1/GFPT2 confirmed in this study? 01/10/2018

The interaction between PPP2R2A and GFPT1/GFPT2 was further confirmed through methods such as immunofluorescence co-localization, GST Pull-down, and immunoprecipitation.

What is PPP2R2A, and what role does it play in cancer cell survival and growth? 10/29/2016

PPP2R2A is one of the regulatory subunits of the PP2A phosphatase. Past research reports indicate that PPP2R2A can promote tumor cell survival and growth.

How did the study demonstrate the direct interaction between PPP2R2A and GFPT2? 04/21/2016

The study used immunofluorescence co-localization, GST Pull-down, and immunoprecipitation methods to further confirm the direct interaction between PPP2R2A and GFPT2.

What is the role of GFPT2 in cellular processes, especially in breast cancer cells? 01/28/2016

GFPT2 is a rate-limiting enzyme in the O-GlcNAc glycosylation modification pathway. In breast cancer cells (MDA-MB-231), downregulation of PPP2R2A led to an increase in protein O-GlcNAc glycosylation levels.

Customer Reviews (3)

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Reviews
09/12/2022

    We observed remarkable consistency in product performance across multiple batches, reducing variability in our experiments.

    11/30/2021

      The reliability of the product's quality and effectiveness from one batch to another instilled confidence in its usage.

      08/03/2020

        The product's batch-to-batch consistency was a key factor in the success of our long-term research projects.

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