PPP3CC Protein, protein phosphatase 3, catalytic subunit, gamma isozyme

PPP3CC

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PPP3CC

Official Full Name protein phosphatase 3, catalytic subunit, gamma isozyme
Background Calcineurin is a calcium-dependent, calmodulin-stimulated protein phosphatase involved in the downstream regulation of dopaminergic signal transduction. Calcineurin is composed of a regulatory subunit and a catalytic subunit. The protein encoded by this gene represents one of the regulatory subunits that has been found for calcineurin. Three transcript variants encoding different isoforms have been found for this gene.
Synonyms PPP3CC; protein phosphatase 3, catalytic subunit, gamma isozyme; protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform , protein phosphatase 3 (formerly 2B), catalytic subunit, gamma isoform (calcineurin A gamma); serine/threonine-protein
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PPP3CC-736H Recombinant Human PPP3CC Protein (2-512 aa), His-tagged E.coli His
    Human PPP3CC-2913HCL Recombinant Human PPP3CC 293 Cell Lysate HEK293 N/A
    Mouse PPP3CC-13268M Recombinant Mouse PPP3CC Protein Mammalian Cell His

    PPP3CC involved in several pathways and played different roles in them. We selected most pathways PPP3CC participated on our site, such as MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP3CC were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    MAPK signaling pathway NLK; PPM1NB; PPM1AA; IL1B; ARRB2A; FLNC; CACNA1C; TGFBR2; FOS; PRKCG
    Calcium signaling pathway AVPR1B; ADORA2AB; CHRNA7; PLCD3A; PLCD1B; PLCB2; ATP2A1L; PTGER3; TNNC1B; VDAC1
    cGMP-PKG signaling pathway GTF2IRD1; RAF1; ATP1B4; MEF2C; GNAI1; ITPR1; GUCY1B3; GUCY1A3; MAP2K1; PIK3R1
    Oocyte meiosis CALM3; PPP1CB; PPP2R5B; PPP1CAB; PPP2R5E; FBXW11; SMC1A; CDC16; CAMK2G; CALM3B
    Apoptosis NFKB1; PRKAR2AA; CASP6L1; PRKAR2B; CYCSB; RIPK1; PPP3CCB; TNFSF10; PLEC; TRAF2
    Wnt signaling pathway DKK2; RHOAC; PSEN1; WNT3A; LEF1; WNT9A; FZD3; PPP3CCB; FZD9; TP53
    Axon guidance RHOD; EPHB3A; MAPK1; KALRN; FGF18B; KCNQ2; EFNA3B; Ntng2; CREB1B; RASGEF1A
    VEGF signaling pathway MAPK12; AKT2; MAP2K1; MAPK12A; PLA2G4D; RAC3A; MAPKAPK2A; HRAS; PTK2AA; RAC1
    Osteoclast differentiation IL1A; IFNGR2; SIRPG; NFKB1; CYBB; CYLD; FCGR2C; FYN; SIRPA; IFNGR1
    Natural killer cell mediated cytotoxicity IFNA5; LCK; ICAM2; Fasl; PIK3R2; SYK; PTPN6; LCP2; KLRD1; IFNA1
    T cell receptor signaling pathway IKBKG; MAPK1; PTPRC; CD3E; SLA1; IL5; ICOS; NCK2; GRB2; MAPK13
    B cell receptor signaling pathway PTPN18; NRAS; ITPR2; NFATC2; CD81; PIK3CB; BTK; RELA; CDK6; PLEKHA1
    Long-term potentiation CAMK2D; MAPK1; PPP3CC; RPS6KA3; GRIA1; CALML3; RPS6KA6; RAP1B; MAP2K1; GRIN2D
    Glutamatergic synapse PLA2G4F; GNG3; PRKACA; ITPR3; GNGT1; PPP3R1; SLC38A1; GNB1; PLA2G4A; GRIK4
    Dopaminergic synapse TH; GNAS; PPP2R3A; AKT2; CALM3; DRD3; PRKCA; GNG2; PLCB2; GNG10
    Oxytocin signaling pathway RAF1; MYLK4; PPP3CC; CALML5; CCND1; PPP3CA; PIK3R3; CACNG1; PPP1CA; PPP1CB
    Glucagon signaling pathway PHKA2; PRKAG2; SMEK2; FBP1; SIK2; PYGM; PDHA2; FOXO1; PLCB4; PPP3CC
    Renin secretion GNAI3; PDE1C; PRKACA; GUCY1A3; PPP3CA; PLCB2; GUCY1B3; ITPR3; CALM4; PTGER4
    Alzheimers disease ATP5A1; CALM1; ADAM17; TNFRSF1A; PLCB2; UQCRC1; EIF2AK3; UQCRC2; ATP5H; APP
    Amyotrophic lateral sclerosis (ALS) PPP3CB; GRIN2B; MAPK13; NEFM; CCS; GPX1; APAF1; MAP2K6; MAP2K3; SOD1
    Amphetamine addiction PPP3R2; DRD1A; MAOB; CAMK2A; PPP3CB; CREB3L4; CAMK4; SLC18A2; PPP1CB; FOSB
    Tuberculosis HLA-DRB1; IFNB1; SPHK1; CAMK2G; FCGR1; IFNA8; STAT1; IFNA2; IFNA16; FCGR2A
    HTLV-I infection SFPI1; TGFBR2; NFKB1; WNT5A; TGFB1; NFKBIA; MYBL1; DVL2; PPP3R1; GPS2

    PPP3CC has several biochemical functions, for example, calmodulin binding, metal ion binding, phosphoprotein phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP3CC itself. We selected most functions PPP3CC had, and list some proteins which have the same functions with PPP3CC. You can find most of the proteins on our site.

    Function Related Protein
    calmodulin binding CNN1; MYO10; CAMK1GB; MYO5B; CAMK2G1; AEBP1; DDX5; CNN2; CAMSAP1; TRPV1
    metal ion binding CDC7; PAPD4; GTF3A; ACACA; ACSM2; MTBL; SCRT1; ZFP12; GDE1; ZFP354C
    phosphoprotein phosphatase activity PPM1LA; DUSP9; MTM1; PPP3CCA; TIMM50; PPM1NB; PTPRK; DUSP22A; PPEF2; TENC1
    protein binding EIF3G; TRIM69; FMNL1; CCDC59; FBXW2; ERCC6; MPDU1; GTF3C6; ZW10; SSTR3

    PPP3CC has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP3CC here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP3CC.

    AMPH; CSNK2B; HAX1; SDC2; ybfM; yaaO; ITPKC; THAP7

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