ppp5c
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  • Official Full Name
  • protein phosphatase 5, catalytic subunit
  • Background
  • Protein phosphatase 5 (PP5) is a member of the serine/threonine phosphatase family that also includes PP1, PP2A and PP2B. PP5 uniquely contains an amino-terminal regulatory domain with three tetratricopeptide repeat (TPR) motifs and a carboxy-terminal cat
  • Synonyms
  • PPP5C; protein phosphatase 5, catalytic subunit; PPP5; serine/threonine-protein phosphatase 5; PP5; PP-T; protein phosphatase T; PPT; FLJ36922; FLJ55954
Cat.#:PPP5C-12HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human PPP5C protein, GST-tagged
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Cat.#:PPP5C-177HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Protein Phosphatase 5, Catalytic Subunit
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Cat.#:PPP5C-178HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPP5C, Catalytic Domain
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Cat.#:PPP5C-1927HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPP5C, GST-tagged
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Cat.#:PPP5C-27638THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPP5C, His-tagged
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Cat.#:PPP5C-4645RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PPP5C Protein
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Cat.#:PPP5C-3578RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PPP5C Protein, His-tagged
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Cat.#:PPP5C-2271ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PPP5C
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Cat.#:PPP5C-2908HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PPP5C 293 Cell Lysate
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Involved Pathway

PPP5C involved in several pathways and played different roles in them. We selected most pathways PPP5C participated on our site, such as MAPK signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP5C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
PDGFRB; ARRB2B; RPS6KA3B; MAP2K1; RAC3A; RAC2; MAPK14A; FGF2; ARR3A; FGF4

Protein Function

PPP5C has several biochemical functions, for example, G-protein alpha-subunit binding, RNA binding, heat shock protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP5C itself. We selected most functions PPP5C had, and list some proteins which have the same functions with PPP5C. You can find most of the proteins on our site.
Function
Related Protein
Function G-protein alpha-subunit binding
Related Protein PPP5C; IGF1R; RIC8A; LPAR3; AGTR1A; DRD1A; CRHR1; RIC8B; RGS4; RIC8
Function RNA binding
Related Protein GRB7; SRSF3; SPI1; RBM17; RBM48; CNP; DPPA5A; RNMTL1A; DAZL; RTCA
Function heat shock protein binding
Related Protein KCNJ11; APAF1; DNAJC9; SSUH2.2; FAF1; PPID; DLST; DNAJC7; HSPA1A; DNAJA2
Function identical protein binding
Related Protein ASS1; EIF2AK3; CD74; BAX; CIDEB; GLUD1; GUCY2E; PVRL2; TRIM23; CAD
Function lipid binding
Related Protein FAM123A; PTGS1; APOA4B.2; TRIP10; CADPS; APOA2; BPIFA3; Fert2; DBI; APOA5
Function metal ion binding
Related Protein MT1; CYP2AA7; ZNF598; ZNF823; ZNF488; ZDHHC18A; CHORDC1B; ZFP335; ZSWIM7; NRAP
Function microtubule binding
Related Protein KIF15; KIF5B; GAS2L3; CEP57; CEP350; KLC3; RGS14; TUBGCP5; KIF1C; PAFAH1B1
Function phosphoprotein phosphatase activity
Related Protein PTPRU; PPP1CAB; CDC14AA; PPM1AA; PPM1BB; CTDNEP1; DUSP28; PHPT1; CDC14A; PPP3CC
Function protein binding
Related Protein KCNB1; HMOX1; TTC23L; PAX5; TOR1A; NLRP2; GMNN; CUL2; DDI1; USP12
Function protein serine/threonine phosphatase activity
Related Protein PP2D1; MTMR4; TAB1; PPP2R5D; PPP1R3D; PPM1J; PPP4C; CTDNEP1A; PPM1H; PPM1LB
Function signal transducer activity
Related Protein LGR4; TAS2R110; MAPKAPK5; IL1R1; GPR30; TAS2R117; SH2B3; TAS2R113; TAS2R109; OLFR488

Interacting Protein

PPP5C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP5C here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP5C.
HSP90AA1; HSP90AB1; ESR1; CDC37

PPP5C Related Articles

You, S; Piali, L; et al. Therapeutic Use of a Selective S1P(1) Receptor Modulator Ponesimod in Autoimmune Diabetes. PLOS ONE 8:-(2013).
Fusco, DN; Brisac, C; et al. A Genetic Screen Identifies Interferon-alpha Effector Genes Required to Suppress Hepatitis C Virus Replication. GASTROENTEROLOGY 144:1438-U210(2013).