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PSMD14

  • Official Full Name

    proteasome (prosome, macropain) 26S subunit, non-ATPase, 14

  • Overview

    This gene encodes a component of the 26S proteasome. The 26S proteasome is a large multiprotein complex that catalyzes;the degradation of ubiquitinated intracellular proteins. The encoded protein is a component of the 19S regulatory cap;complex of the 26S proteasome and mediates substrate deubiquitination. A pseudogene of this gene is also located on;the long arm of chromosome 2.
  • Synonyms

    PSMD14; proteasome (prosome, macropain) 26S subunit, non-ATPase, 14; 26S proteasome non-ATPase regulatory subunit 14; pad1; POH1; Rpn11; 26S proteasome regulatory subunit rpn11; 26S proteasome-associated PAD1 homolog 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • Sf9 Insect Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • MBP
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PSMD14-6978H Recombinant Human PAD1, GST-tagged Sf9 Insect Cell GST Full length
Human PSMD14-2030H Recombinant Human PSMD14, GST-tagged E.coli GST 1-95aa
Human PSMD14-2751HCL Recombinant Human PSMD14 293 Cell Lysate HEK293 N/A
Human PSMD14-40H Recombinant Human PSMD14 Protein, GST-tagged Insect Cell GST
Human PSMD14-6158H Recombinant Human PSMD14 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PSMD14-2253H Recombinant Human PSMD14 protein, MBP&His-tagged Insect Cell MBP&His 1-310aa
Mouse Psmd14-5192M Recombinant Mouse Psmd14 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Cynomolgus Monkey PSMD14-824C Recombinant Cynomolgus PSMD14 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey PSMD14-567C Recombinant Cynomolgus Monkey PSMD14 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey PSMD14-567C-B Recombinant Cynomolgus Monkey PSMD14 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque PSMD14-3670R Recombinant Rhesus monkey PSMD14 Protein, His-tagged Mammalian Cell His
Rhesus Macaque PSMD14-3488R Recombinant Rhesus Macaque PSMD14 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PSMD14-3488R-B Recombinant Rhesus Macaque PSMD14 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PSMD14-5426Z Recombinant Zebrafish PSMD14 Mammalian Cell His
Chicken PSMD14-2914C Recombinant Chicken PSMD14 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PSMD14 involved in several pathways and played different roles in them. We selected most pathways PSMD14 participated on our site, such as APC/C-mediated degradation of cell cycle proteins, APC/C:Cdc20 mediated degradation of Securin, APC/C:Cdc20 mediated degradation of mitotic proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSMD14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
APC/C-mediated degradation of cell cycle proteinsUBE2C;PSMD10;ANAPC10;PSMD5;PSMA8;PSMD14;PSME3;PSMD9;NEK2
APC/C:Cdc20 mediated degradation of SecurinUBE2C;ANAPC10;PSMD14;PSME3;PSMD10;PSMD5;PSMD9;PSMA8
APC/C:Cdc20 mediated degradation of mitotic proteinsPSMD9;PSMD14;ANAPC10;PSMD10;UBE2C;PSMD5;PSMA8;NEK2;PSME3
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1AURKB;PSMD9;PSMD14;PSME3;ANAPC10;PSMD10;UBE2C;PSMA8;PSMD5
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpointPSMD14;ANAPC10;PSME3;UBE2C;PSMD9;PSMA8;PSMD10;PSMD5;NEK2
ARMS-mediated activationMARK3;FGF10B;PEA15A;PSMD5;FGFR1B;DAB2IPB;DUSP2;RASGRP4;CSF2RA
AUF1 (hnRNP D0) binds and destabilizes mRNAPSMD10;HNRNPD;PSMD14;PSMD9;EIF4G1;PSMD5;PSME3;PSMA8
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteinsPSMD5;PSMA8;NEK2;ANAPC10;PSMD14;PSME3;PSMD9;PSMD10;UBE2C

PSMD14 has several biochemical functions, for example, endopeptidase activator activity, metal ion binding, metallopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PSMD14 itself. We selected most functions PSMD14 had, and list some proteins which have the same functions with PSMD14. You can find most of the proteins on our site.

Function Related Protein
endopeptidase activator activityPSME1;PSME3;SFRP2;PSME2;PSMD14;ADRM1
metal ion bindingRARGB;ZNF643;TAF1B;HAGHL;RHOV;NME7;BAK1;MAP3K4;TGM2B
metallopeptidase activityCPD;AFG3L2;HE2;ECEL1;MMP14A;ADAMTS9;C6AST3;ADAMTSL1;BMP1
proteasome bindingPSMG1;ID1;USP14;DNAJB2;USP13;PSMF1;PSMD14;ADRM1;UBD
protein bindingMAGEA4;SET;ARHGEF4;MRPL10;SNX9;SNX1;C9orf86;SP100;CLOCK

PSMD14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSMD14 here. Most of them are supplied by our site. Hope this information will be useful for your research of PSMD14.

PSMD7; PSMD6; UCHL5; MEOX2; PSMD11; PSMD12

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