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Official Full Name proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
Background This gene encodes a component of the 26S proteasome. The 26S proteasome is a large multiprotein complex that catalyzes;the degradation of ubiquitinated intracellular proteins. The encoded protein is a component of the 19S regulatory cap;complex of the 26S proteasome and mediates substrate deubiquitination. A pseudogene of this gene is also located on;the long arm of chromosome 2.
Synonyms PSMD14; proteasome (prosome, macropain) 26S subunit, non-ATPase, 14; 26S proteasome non-ATPase regulatory subunit 14; pad1; POH1; Rpn11; 26S proteasome regulatory subunit rpn11; 26S proteasome-associated PAD1 homolog 1
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PSMD14-2030H Recombinant Human PSMD14, GST-tagged E.coli GST
    Human PSMD14-2751HCL Recombinant Human PSMD14 293 Cell Lysate HEK293 N/A
    Human PSMD14-6978H Recombinant Human PAD1, GST-tagged Sf9 Insect Cell GST
    Cynomolgus Monkey PSMD14-824C Recombinant Cynomolgus PSMD14 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque PSMD14-3670R Recombinant Rhesus monkey PSMD14 Protein, His-tagged Mammalian Cell His
    Chicken PSMD14-2914C Recombinant Chicken PSMD14 Mammalian Cell His
    Zebrafish PSMD14-5426Z Recombinant Zebrafish PSMD14 Mammalian Cell His

    PSMD14 involved in several pathways and played different roles in them. We selected most pathways PSMD14 participated on our site, such as content, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSMD14 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    APC/C-mediated degradation of cell cycle proteins CDK2; NEK2; AURKB; PSMD14; PSMD5; ANAPC10; PSMA8; PSME3; PSMD9; PSMD10
    APC/C:Cdc20 mediated degradation of Securin PSMD9; ANAPC10; UBE2C; PSMA8; PSMD5; PSMD10; PSME3; PSMD14
    APC/C:Cdc20 mediated degradation of mitotic proteins PSMD10; NEK2; PSMD5; PSME3; PSMA8; UBE2C; ANAPC10; PSMD14; PSMD9
    APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 AURKB; PSMD9; PSMD5; PSME3; PSMA8; ANAPC10; PSMD10; PSMD14; UBE2C
    APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint PSMD9; PSMD14; PSMD10; PSMA8; UBE2C; ANAPC10; NEK2; PSMD5; PSME3
    ARMS-mediated activation JAK2; RASGEF1A; CNKSR1; CSF2; NRG3; CSK; DUSP9; FGF10B; SPNA2; KIDINS220B
    AUF1 (hnRNP D0) binds and destabilizes mRNA PSMD9; HNRNPD; EIF4G1; PSMD14; PSMD10; PSMD5; PSME3; PSMA8
    Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins PSMD10; PSMA8; NEK2; PSMD9; PSMD5; PSMD14; UBE2C; ANAPC10; PSME3

    PSMD14 has several biochemical functions, for example, Content. Some of the functions are cooperated with other proteins, some of the functions could acted by PSMD14 itself. We selected most functions PSMD14 had, and list some proteins which have the same functions with PSMD14. You can find most of the proteins on our site.

    Function Related Protein
    endopeptidase activator activity SFRP2; ADRM1; PSMD14; PSME3; PSME1; PSME2
    metal ion binding DMRT1; ATP1A3A; NOS2B; KSR1; PPP2R3C; RPP21; OSR1; KSR2; ISL2B; ZDHHC5A
    metallopeptidase activity COPS5; BMP1A; MMP30; ADAM30; ADAM15; AGBL1; MMP14B; BRCC3; ADAM20; ADAMTS13
    proteasome binding ADRM1; USP14; ID1; UCHL5; BAG6; USP13; PSMD14; UBD; PSMF1; DNAJB2
    protein binding TTLL10; LANCL1; PTK7; SHISA3; HS3ST5; SELS; ABCF1; RECQL; PLXNC1; RUSC1

    PSMD14 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSMD14 here. Most of them are supplied by our site. Hope this information will be useful for your research of PSMD14.


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