ptpmt1
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  • Official Full Name
  • protein tyrosine phosphatase, mitochondrial 1
  • Background
  • Protein phosphatase that specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells.
  • Synonyms
  • PTPMT1; protein tyrosine phosphatase, mitochondrial 1; protein-tyrosine phosphatase mitochondrial 1; DUSP23; MOSP; PLIP; PTEN-like phosphatase; phosphoinositide lipid phosphatase; NB4 apoptosis/differentiation related protein; PNAS-129; FLJ46081
Cat.#:PTPMT1-1568HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Protein Tyrosine Phosphatase, Mitochondrial 1, His-tagged
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Cat.#:PTPMT1-2547HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PTPMT1, His tagged
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Cat.#:PTPMT1-31117THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PTPMT1, His-tagged
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Cat.#:PTPMT1-3703RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PTPMT1 Protein, His-tagged
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Cat.#:PTPMT1-5223CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PTPMT1
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Cat.#:PTPMT1-5044ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PTPMT1
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Cat.#:PTPMT1-1436HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PTPMT1 cell lysate
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Involved Pathway

PTPMT1 involved in several pathways and played different roles in them. We selected most pathways PTPMT1 participated on our site, such as 3-phosphoinositide degradation, Glycerophospholipid biosynthesis, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PTPMT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
3-phosphoinositide degradation
INPP5F; PTPMT1
Glycerophospholipid biosynthesis
PLD4; ABHD4; CPNE3; PNPLA8; CPNE6; CDS1; CPNE1; STIL; PEMT; PLB1
Metabolism
ARSE; ACOT13; SLC25A15A; GLTPD1; SLC52A3; SULT4A1; SURF1; B3GAT2; DPYD; AQP1A.2
Metabolism of lipids and lipoproteins
COQ7; FABP12; ACSF3; GC; MED6; TPTE; CHAT; ALOX5B.3; FIG4; BCHE
Phospholipid metabolism
SACM1LB; AWAT2; PTPMT1; SLC44A5B; CPNE1; CEPT1A; SACM1L; CDS1; CEPT1; ABHD3
Synthesis of PG
PLD6; PTPMT1

Protein Function

PTPMT1 has several biochemical functions, for example, phosphatidylglycerophosphatase activity, phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PTPMT1 itself. We selected most functions PTPMT1 had, and list some proteins which have the same functions with PTPMT1. You can find most of the proteins on our site.
Function
Related Protein
Function phosphatidylglycerophosphatase activity
Related Protein PTPMT1
Function phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity
Related Protein INPP5E; INPP5B; OCRL; EPM2A; SYNJ2; PTPMT1
Function protein binding
Related Protein E2F1; UBE2D4; ANKRD10; THOC7; SPTSSB; CRH; CEACAM6; MMP20; DCSTAMP; CCDC12
Function protein tyrosine phosphatase activity
Related Protein PTPN23; DUSP22; PTPN3; DUSP18; PALD1B; DUSP8A; PTPRNA; EVLA; MTMR1B; DUSP19
Function protein tyrosine/serine/threonine phosphatase activity
Related Protein DUSP14; DUSP15; EYA3; DUSP22B; DUPD1; DUSP23B; DUSP26; SACM1L; DUSP22A; CTDSPL2B

Interacting Protein

PTPMT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTPMT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PTPMT1.
MDFI; RGS20; KRTAP2-3; TRIM27; KRTAP5-9; KRTAP10-7

PTPMT1 Related Articles

Park, JS; Lee, SJ; et al. Gastric Autoantigenic Proteins in Helicobacter Pylori Infection. YONSEI MEDICAL JOURNAL 54:1342-1352(2013).
Matsumoto, C; Ito, M; et al. Genes that characterize T-3-predominant Graves' thyroid tissues. EUROPEAN JOURNAL OF ENDOCRINOLOGY 168:137-144(2013).