ptpn3
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  • Official Full Name
  • protein tyrosine phosphatase, non-receptor type 3
  • Background
  • The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • PTPN3; protein tyrosine phosphatase, non-receptor type 3; tyrosine-protein phosphatase non-receptor type 3; PTPH1; protein-tyrosine phosphatase H1; cytoskeletal-associated protein tyrosine phosphatase; PTP-H1; DKFZp686N0569
Cat.#:PTPN3-8090HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PTPN3 protein, His & T7-tagged
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Cat.#:PTPN3-13685MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PTPN3 Protein
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Cat.#:Ptpn3-8091MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Ptpn3 protein, His & T7-tagged
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Cat.#:PTPN3-2683HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PTPN3 293 Cell Lysate
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Protein Function

PTPN3 has several biochemical functions, for example, ATPase binding, cytoskeletal protein binding, phosphotyrosine binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PTPN3 itself. We selected most functions PTPN3 had, and list some proteins which have the same functions with PTPN3. You can find most of the proteins on our site.
Function
Related Protein
Function ATPase binding
Related Protein FXYD1; ATP6V1G3; TAF9; ABCA1; NOP58; METTL21A; ATP6V0A1; SNTA1; SELS; NUFIP1
Function cytoskeletal protein binding
Related Protein EPB41L3B; PACSIN1; ACTN2; PDLIM3; LIN7C; CORO1A; MYPN; NF2A; CDK5; ABI1
Function phosphotyrosine binding
Related Protein CBL; MAPK1; ZAP70; ACP2; LDLRAP1; CBLB; CBLC; GRB2; FGR; MAPK3
Function protein binding
Related Protein BORA; SIX4; TMEM79; BCL2; SPSB4; HIC1; FAM109B; MYLIP; BATF2; IKBKB
Function protein tyrosine phosphatase activity
Related Protein DUSP6; MTMR1B; PTPN11; DUSP10; DUSP14; DUSP23A; CDKN3; PTPN1; PTPRG; PTPN11A
Function sodium channel regulator activity
Related Protein AGT; FXYD5; SGK2; SCN1BA; FXYD1; FXYD7; SGK1; FGF13; NEDD4L; SGK2B

Interacting Protein

PTPN3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTPN3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PTPN3.
GHR; YWHAG; LMO1; YWHAB; AKR1C1; DIP2A; ZCCHC10