ralb
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  • Official Full Name
  • v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein)
  • Background
  • RalA and RalB are members of the Ras family of small GTPases and are highly homologous in protein sequence. The functions of RalA and RalB are distinct yet overlapping. By binding to various effector proteins, RalA and RalB serve as important GTP sensors
  • Synonyms
  • RALB; v-ral simian leukemia viral oncogene homolog B (ras related; GTP binding protein); ras-related protein Ral-B; RAS-like protein B; GTP binding protein
Cat.#:RALB-117HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RALB, GST-tagged
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Cat.#:RALB-2166HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RALB, GST-tagged
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Cat.#:RALB-28237THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RALB, His-tagged
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Cat.#:RALB-3390HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RALB, His-tagged
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Cat.#:RALB-4916RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat RALB Protein
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Cat.#:RALB-3778RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey RALB Protein, His-tagged
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Cat.#:RALB-2543HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RALB 293 Cell Lysate
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Involved Pathway

RALB involved in several pathways and played different roles in them. We selected most pathways RALB participated on our site, such as Ras signaling pathway, Rap signaling pathway, Phospholipase D signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RALB were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ras signaling pathway
FGF19; AKT2; RHOA; CALML5; SHC4; PAK7; GNB3; RALBP1; FGF17; GRIN2A
Rap signaling pathway
MAPK1; ARAP3; GNAI3; ITGA2B; PGF; FGFR2; FGF20; PARD3; RAC3; ITGB2
Phospholipase D signaling pathway
MAPK3; PDGFA; RHOA; IL-8; GRM4; FCER1A; AGPAT4; PLCB3; AKT2; PLCG1
Pathways in cancer
FADD; F2RL3; GNB1; BCL2; Fasl; WNT7B; SUFU; BID; CDH1; TGFA
Pancreatic cancer
PIK3CD; MAPK3; RALBP1; CCND1; PIK3CG; NFKB1; PIK3CB; PIK3R2; TGFB1; PIK3R5

Protein Function

RALB has several biochemical functions, for example, ATPase binding, GDP binding, GTP binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RALB itself. We selected most functions RALB had, and list some proteins which have the same functions with RALB. You can find most of the proteins on our site.
Function
Related Protein
Function ATPase binding
Related Protein PKD2; SLN; UBXN1; TOR1AIP1; SYVN1; SNTA1; PLN; USP25; PIH1D1; NHP2L1
Function GDP binding
Related Protein SRP54A; PRPS2; RAB27A; RHOA; ARF1; RAB35; ARL3; RAB2A; SEPT12; RAB7A
Function GTP binding
Related Protein GTPBP8; SAR1AB; RRAGCB; EEF2B; RAC1; GBP6; LRRK1; RAB40C; RND2; DNM3A
Function GTPase activity
Related Protein GNAZ; GNB5; EFTUD1; TUBG1; MXE; RALB; RHEB; TUBG2; RAB42A; EEF1A1B
Function protein binding
Related Protein KCNG3; SMAD5; DSN1; FNIP1; TNFAIP8; DLL4; C21orf119; BSG; RFWD3; CREBBP
Function ubiquitin protein ligase binding
Related Protein POLR2A; TNFRSF14; PRKACB; CHEK2; PML; BAG6; PIAS1; ATP6V0C; PA2G4; UBE2G2

Interacting Protein

RALB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RALB here. Most of them are supplied by our site. Hope this information will be useful for your research of RALB.
CALM1; Ccnd1; Ralbp1; RALBP1; 1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate; pi3p; Exoc2; ATG12; ATP6V1A; Flnb; ATG5; Coro1c; Gabarapl1; BECN1; Exoc3; Atg5