Retinoids exert biologic effects such as potent growth inhibitory and cell differentiation activities and are used in the treatment of hyperproliferative dermatological diseases. These effects are mediated by specific nuclear receptor proteins that are members of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. RARRES1, RARRES2, and RARRES3 are genes whose expression is upregulated by the synthetic retinoid tazarotene. RARRES3 is thought act as a tumor suppressor or growth regulator.
RARRES3 has several biochemical functions, for example, phospholipase A2 activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RARRES3 itself. We selected most functions RARRES3 had, and list some proteins which have the same functions with RARRES3. You can find most of the proteins on our site.
Function phospholipase A2 activity
Related Protein PLA2G16; PRDX6; PLA2G2A; PLA2G2D; PLA2G1B; PLB1; PLA2G4AA; OC90; PLA2G10; LCAT
Function protein binding
Related Protein TICAM2; NUP62L; BYSL; NUDT2; DEAF1; CDC42EP2; PIM1; SKAP2; PLCG2; DYSFIP1
RARRES3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RARRES3 here. Most of them are supplied by our site. Hope this information will be useful for your research of RARRES3.