rfx2
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  • Official Full Name
  • regulatory factor X, 2 (influences HLA class II expression)
  • Background
  • This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008]
  • Synonyms
  • RFX2; regulatory factor X, 2 (influences HLA class II expression); DNA-binding protein RFX2; regulatory factor X 2; DNA binding protein RFX2; trans-acting regulatory factor 2; HLA class II regulatory factor RFX2;
Cat.#:RFX2-2264HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RFX2, GST-tagged
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Cat.#:RFX2-14113MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse RFX2 Protein
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Cat.#:RFX2-5008RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat RFX2 Protein
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Cat.#:RFX2-2085ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish RFX2
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Cat.#:RFX2-2399HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human RFX2 293 Cell Lysate
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Protein Function

RFX2 has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RFX2 itself. We selected most functions RFX2 had, and list some proteins which have the same functions with RFX2. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein ZNF446; ZNF711; ZNF529; ZFP710; HNRPDL; PTF1A; HIST1H2AE; PSMC3IP; TSN; MXD3
Function RNA polymerase II core promoter proximal region sequence-specific DNA binding
Related Protein SMAD4; RBPJL; NFIA; NKX2-5; EN1; MAFB; FOXL2; MEF2B; KCNA3; SIX1
Function transcription factor activity, sequence-specific DNA binding
Related Protein BACH2; POU4F1; ETV5B; ZBTB25; ESRRGA; TRP53; TCF7L1A; AHRRB; PDX1; MAFGB

Interacting Protein

RFX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RFX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of RFX2.
RFX6; MDFI