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Official Full Name regulatory factor X, 2 (influences HLA class II expression)
Background This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008]
Synonyms RFX2; regulatory factor X, 2 (influences HLA class II expression); DNA-binding protein RFX2; regulatory factor X 2; DNA binding protein RFX2; trans-acting regulatory factor 2; HLA class II regulatory factor RFX2;
    • Species :
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • C-Myc/DDK
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RFX2-369H Recombinant Human RFX2 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
    Mouse Rfx2-5480M Recombinant Mouse Rfx2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human RFX2-2264H Recombinant Human RFX2, GST-tagged E.coli GST
    Human RFX2-2399HCL Recombinant Human RFX2 293 Cell Lysate HEK293 N/A
    Mouse RFX2-14113M Recombinant Mouse RFX2 Protein Mammalian Cell His
    Rat RFX2-5008R Recombinant Rat RFX2 Protein Mammalian Cell His
    Zebrafish RFX2-2085Z Recombinant Zebrafish RFX2 Mammalian Cell His

    RFX2 involved in several pathways and played different roles in them. We selected most pathways RFX2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RFX2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    RFX2 has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RFX2 itself. We selected most functions RFX2 had, and list some proteins which have the same functions with RFX2. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding LYL1; XRCC5; PCGF2; PRRXL1; ESR2A; SCML4; ZNF507; LTF; ZBTB2; GPBP1L1
    RNA polymerase II core promoter proximal region sequence-specific DNA binding ESRRA; HLTF; BCL11B; GMEB1; FOXD1; SIX5; ZNF264; RELA; NKX6-1; IRF1
    transcription factor activity, sequence-specific DNA binding HOXA3; ZNF71; SIM1; ATF5; DMRTA1; CREB1B; NANOG; STAT5B; PBX2; TEAD4

    RFX2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RFX2 here. Most of them are supplied by our site. Hope this information will be useful for your research of RFX2.

    RFX6; MDFI

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