RFX3 Protein, regulatory factor X, 3 (influences HLA class II expression)

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RFX3

Official Full Name	regulatory factor X, 3 (influences HLA class II expression)
Background	This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Two transcript variants encoding different isoforms have been described for this gene, and at least one of the variants utilizes alternative polyadenylation signals.
Synonyms	RFX3; regulatory factor X, 3 (influences HLA class II expression); transcription factor RFX3; DNA binding protein RFX3; Regulatory factor X 3; RFX3_HUMAN; OTTHUMP00000020993; OTTHUMP00000020994; bA32F11.1

Species :
Human
Mouse
Zebrafish

Source :
E.coli
HEK293
Mammalian Cell

Tag :
His
N/A

Species	Cat.#	Product name	Source (Host)	Tag
Human	RFX3-2265H	Recombinant Human RFX3, His-tagged	E.coli	His
Human	RFX3-2398HCL	Recombinant Human RFX3 293 Cell Lysate	HEK293	N/A
Mouse	RFX3-14114M	Recombinant Mouse RFX3 Protein	Mammalian Cell	His
Zebrafish	RFX3-4990Z	Recombinant Zebrafish RFX3	Mammalian Cell	His

Involved Pathway Protein Function Interacting Protein

RFX3 involved in several pathways and played different roles in them. We selected most pathways RFX3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RFX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

RFX3 has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RFX3 itself. We selected most functions RFX3 had, and list some proteins which have the same functions with RFX3. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	RREB1; RUNX2A; ZNF124; GCM1; RPP21; CDX1B; PHC2B; PIN4; ZKSCAN17; TCEB3
RNA polymerase II core promoter proximal region sequence-specific DNA binding	NFIB; HHEX; SKIL; FEZF2; ZNF253; RBPJ; MEF2A; ARNT2; IFI203; AKNA
protein binding	CCK; EBF1; DPYSL4; GADD45A; TGIF2LY; MYBPC3; RHOT2; NIPSNAP3A; STAT3; PPP2R5C
transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding	SOX17; POU3F3; FOXF2A; NKX2; USF1; NR5A2; SPI1; ATF1; USF2; CEBPA
transcription factor activity, sequence-specific DNA binding	CREB5; TSC22D4; PRDM15; SMAD5; IKZF3; RCAN1; TBX10; NKX3; CBFB; HIST1H2AH
transcription regulatory region DNA binding	IKZF2; MEN1; TAF7; CDK9; SFPQ; HNF1A; SMAD3; BCOR; FOXI1; HDAC1

RFX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RFX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of RFX3.

FHL2; FHL3; TRIP6; TRAF2; RFX6

RFX3 Protein, regulatory factor X, 3 (influences HLA class II expression)

RFX3

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RFX3

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