|Official Full Name||regulatory factor X, 3 (influences HLA class II expression)|
|Background||This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X2, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. Two transcript variants encoding different isoforms have been described for this gene, and at least one of the variants utilizes alternative polyadenylation signals.|
|Synonyms||RFX3; regulatory factor X, 3 (influences HLA class II expression); transcription factor RFX3; DNA binding protein RFX3; Regulatory factor X 3; RFX3_HUMAN; OTTHUMP00000020993; OTTHUMP00000020994; bA32F11.1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
RFX3 involved in several pathways and played different roles in them. We selected most pathways RFX3 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with RFX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
RFX3 has several biochemical functions, for example, DNA binding, RNA polymerase II core promoter proximal region sequence-specific DNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RFX3 itself. We selected most functions RFX3 had, and list some proteins which have the same functions with RFX3. You can find most of the proteins on our site.
|DNA binding||RREB1; RUNX2A; ZNF124; GCM1; RPP21; CDX1B; PHC2B; PIN4; ZKSCAN17; TCEB3|
|RNA polymerase II core promoter proximal region sequence-specific DNA binding||NFIB; HHEX; SKIL; FEZF2; ZNF253; RBPJ; MEF2A; ARNT2; IFI203; AKNA|
|protein binding||CCK; EBF1; DPYSL4; GADD45A; TGIF2LY; MYBPC3; RHOT2; NIPSNAP3A; STAT3; PPP2R5C|
|transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding||SOX17; POU3F3; FOXF2A; NKX2; USF1; NR5A2; SPI1; ATF1; USF2; CEBPA|
|transcription factor activity, sequence-specific DNA binding||CREB5; TSC22D4; PRDM15; SMAD5; IKZF3; RCAN1; TBX10; NKX3; CBFB; HIST1H2AH|
|transcription regulatory region DNA binding||IKZF2; MEN1; TAF7; CDK9; SFPQ; HNF1A; SMAD3; BCOR; FOXI1; HDAC1|
RFX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RFX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of RFX3.
FHL2; FHL3; TRIP6; TRAF2; RFX6