rgs19
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  • Official Full Name
  • regulator of G-protein signaling 19
  • Background
  • G proteins mediate a number of cellular processes. The protein encoded by this gene belongs to the RGS (regulators of G-protein signaling) family and specifically interacts with G protein, GAI3. This protein is a guanosine triphosphatase-activating protein that functions to down-regulate Galpha i/Galpha q-linked signaling. Alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.
  • Synonyms
  • RGS19; regulator of G-protein signaling 19; regulator of G protein signalling 19; GAIP; RGSGAIP; G alpha interacting protein; GNAI3IP; Guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein; G-alpha-interacting protein; G protein signalling regulator 19; regulator of G-protein signalling 19
Cat.#:RGS19-2978HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RGS19, T7-tagged
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Cat.#:RGS19-30744THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RGS19, His-tagged
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Cat.#:RGS19-3363HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Regulator Of G-protein Signaling 19, His-tagged
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Cat.#:RGS19-5017RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat RGS19 Protein
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Cat.#:RGS19-3874RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey RGS19 Protein, His-tagged
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Cat.#:RGS19-5802CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken RGS19
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Cat.#:RGS19-7109ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish RGS19
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Cat.#:RGS19-2379HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human RGS19 293 Cell Lysate
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Cat.#:RGS19-2380HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human RGS19 293 Cell Lysate
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Involved Pathway

RGS19 involved in several pathways and played different roles in them. We selected most pathways RGS19 participated on our site, such as Calcium Regulation in the Cardiac Cell, G alpha (i) signalling events, G alpha (q) signalling events, which may be useful for your reference. Also, other proteins which involved in the same pathway with RGS19 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Calcium Regulation in the Cardiac Cell
RGS11; RGS20; RGS18; FKBP1A; RGS7; GJB2; CASQ1B; CX34.4; GJB3; GJA10
G alpha (i) signalling events
NMU; AGT; ADORA1; S1PR5B; RGS1; ADRA2C; OPN1MW; HEBP1; TAS2R16; RGR
G alpha (q) signalling events
MGLL; TRPC6A; QRFPR; ARHGEF25; PROK2; EDN1; PROKR1; GPRC6A; KALRN; ANXA1B
G alpha (z) signalling events
RGS17; ADRA2B; RGS4; RGS19; ADRA2A; ADRA2C; RGS20
GPCR downstream signaling
ADCYAP1R1; ADCYAP1B; OXGR1A.3; MCF2L; S1PR3; ADCYAP1; ABHD6B; RLN3A; GPR4; GPR65
Gastrin-CREB signalling pathway via PKC and MAPK
ANXA1; NPS; NMS; TRPC7; OXTRL; OPN4A; LTB4R; LPAR1; TRH; NPSR1
Myometrial Relaxation and Contraction Pathways
CNN1; CNN2; RAMP1; RGS11; RGS18; PKIG; RGS20; IGFBP6; GUCA2A; CORIN
Neurotrophic factor-mediated Trk receptor signaling
RIT1; DYNLT1; GIPC1; FAIM; RIT2; RGS19; MCF2L

Protein Function

RGS19 has several biochemical functions, for example, G-protein alpha-subunit binding, GTPase activator activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RGS19 itself. We selected most functions RGS19 had, and list some proteins which have the same functions with RGS19. You can find most of the proteins on our site.
Function
Related Protein
Function G-protein alpha-subunit binding
Related Protein RIC8A; DRD1A; DRD1; IGF1R; OPRM1; PPP5C; RGS19; HTR2B; LPAR1; CRHR1
Function GTPase activator activity
Related Protein RGS7; SOS1; LLGL1; RAB3GAP1; RGS18; RASA1; TBC1D3C; ARHGAP5; ARHGAP26; CHN1
Function protein binding
Related Protein SKP2; STX2; EPC1; SPINK2; CT45A3; H2-AA; HIST1H2BF; PPP1R1A; AGL; P4HA3

Interacting Protein

RGS19 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RGS19 here. Most of them are supplied by our site. Hope this information will be useful for your research of RGS19.
Gnai3; GNAI2; MAPK6; q81s67_bacan; MZT1