Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at BIO-Europe Spring|March 18–20, 2024|Booth #34

RHOA

  • Official Full Name

    ras homolog family member A

  • Overview

    Ras is the name given to a family of related proteins which is ubiquitously expressed in all cells, . All Ras protein family members belong to a class of protein called small GTPase, and are involved in transmitting signals within cells (cellular signal transduction). Ras is the prototypical member of the Ras superfamily of proteins, which are all related in 3D structure and regulate diverse cell behaviours.
  • Synonyms

    RHOA; ras homolog family member A; ARH12, ARHA, ras homolog gene family, member A; transforming protein RhoA; Rho12; RhoA; RHOH12; h12; oncogene RHO H12; rho cDNA clone 12; Aplysia ras-related homolog 12; small GTP binding protein RhoA; ras homolog gene;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • C
  • Myc
  • DDK
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • MYC
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RHOA-33H Active Recombinant Human RHOA protein, His-tagged E.coli His
Human RHOA-179H Active Recombinant Human RHOA, His-tagged E.coli His
Human RHOA-34H Active Recombinant Human RHOA protein, GST-tagged E.coli GST
Human RHOA-3372H Recombinant Human Ras Homolog Gene Family, His-tagged E.coli His
Human RHOA-2290H Recombinant Human RHOA, GST-tagged E.coli GST 1-193aa
Human RHOA-1146H Recombinant Human Ras Homolog Gene Family, Member A, GST-tagged E.coli GST
Human RHOA-1145H Recombinant Human Ras Homolog Gene Family, Member A E.coli N/A
Human RHOA-27379TH Recombinant Human RHOA E.coli N/A
Human RHOA-3975H Recombinant Human RHOA, His tagged Insect Cell His
Human RHOA-313H Recombinant Human RHOA Mammalian Cell His
Human RHOA-1627H Recombinant Human Ras Homolog Gene Family, Member A, His-tagged E.coli His
Human RHOA-32H Recombinant Human RHOA protein, His-tagged E.coli His
Human RHOA-601HCL Recombinant Human RHOA cell lysate Insect Cell N/A
Human RHOA-1182H Recombinant Human RHOA Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human RHOA-160H Recombinant Human RHOA Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human RHOA-5149H Recombinant Human RHOA protein, GST-tagged E.coli GST 1-191aa
Human RHOA-301418H Recombinant Human RHOA, GST-tagged E.coli GST Asn123-Ala161
Human RHOA-2117HFL Recombinant Full Length Human RHOA Protein, C-Flag-tagged Mammalian cells Flag
Human RHOA-2655H Recombinant Human RHOA Protein, His-tagged E.coli N-His Met1-Cys190
Human RHOA-1888H-B Recombinant Human RHOA Protein Pre-coupled Magnetic Beads HEK293
Human RHOA-1888H Recombinant Human RHOA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Rhoa-641M Recombinant Mouse Rhoa Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat RHOA-5035R Recombinant Rat RHOA Protein Mammalian Cell His
Rat RHOA-4694R Recombinant Rat RHOA Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat RHOA-4694R-B Recombinant Rat RHOA Protein Pre-coupled Magnetic Beads HEK293
Chicken RHOA-6269C Recombinant Chicken RHOA Mammalian Cell His
Kit-0768 RhoA Activation ColorimetricAssay Kit (24 assays) N/A
Kit-0769 RhoA Activation Colorimetric Assay Kit (96 assays) N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • RHOA Related Articles
  • RHOA Related Research Area
  • RHOA Related Signal Pathway

RHOA involved in several pathways and played different roles in them. We selected most pathways RHOA participated on our site, such as Ras signaling pathway, Rap signaling pathway, cGMP-PKG signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RHOA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ras signaling pathwaySOS1;PDGFRB;FGFR3;GNG7;SHC3;RAC3;PLA2G5;STK4;CDC42
Rap signaling pathwayFGF4;PIK3R5;PLCG1;PDGFD;RAP1GAP;LPAR2;PRKCA;GNAQ;FGF19
cGMP-PKG signaling pathwayINSR;PDE5A;AGTR1A;MYH7;ATP2A3;MYLK;MEF2C;MYLK4;PRKCE
cAMP signaling pathwayOXTR;FSHB;ATP1B4;PIK3CA;HCN2;ATP2B4;NFATC1;ATP1A1;SLC9A1
Chemokine signaling pathwayNFKBIB;CXCR4;CCL14;RASGRP2;CCR8;PIK3CB;Ccl12;PPBP;CDC42
Sphingolipid signaling pathwayPRKCA;S1PR4;NSMAF;MAP3K5;FCER1G;BID;ABCC1;KRAS;HRAS
Phospholipase D signaling pathwayPPAP2B;KIT;GRM6;GRM1;PTGFR;CYTH2;PTK2B;SHC2;GNAS
EndocytosisERBB3;SH3GLB1A;RAB11FIP5;WASB;NTRK1;MVB12B;DDL-2;RAB5B;HRASB
Vascular smooth muscle contractionPRKCB;ITPR1;PPP1R12C;NPR1A;GNA12A;PLA2G2F;PLA2G2E;CACNA1SB;ADRA1BB
Wnt signaling pathwaySIAH1;FZD1;INVS;CAMK2D2;CCND2A;CAMK2B1;NFATC2;FZD3B;PPP3R2
TGF-beta signaling pathwayBMPR1AB;SMURF1;INHBB;SMAD5;LTBP1;ZFYVE16;BMP7;INHBA;BMPR1BB
Axon guidanceDPYSL5;FGF8B;UNC5C;MET;MYL9;ABLIM3;CLTC;RND1L;CNTN1
Focal adhesionDOCK1;COL2A1B;PARVA;RHOAB;MAPK8B;ACTB;COMP;CAV3;LAMB4
Adherens junctionSRC;WAS;ERBB2;TCF7L1A;WASF2;TGFBR1;BAIAP2;CDH1;CSNK2B
Tight junctionHRASA;SPTAN1;VAPA;GNAI1;TJP2A;RRAS2;CLDN15;CLDN22;CLDN15LB
Platelet activationNOS3;PRKG1;PLCG2;PIK3R5;FGB;PPP1CA;LCP2;ROCK2;PIK3CA
T cell receptor signaling pathwayVAV1;RHOA;NCK2;MAP3K7;CDC42;HRAS;MAP2K7;MAPK1;NFKBIB
Leukocyte transendothelial migrationACTN3;VCL;MYL9;JAM3;PTK2B;PIK3R5;ICAM1;RAP1A;NIPAL1
Neurotrophin signaling pathwayTP53;YWHAE;IRAK2;MAPK9;ZNF274;PTPN11;RPS6KA5;PLCG2;NFKBIA
Regulation of actin cytoskeletonPFN1;RASSF7;RHOAC;INS1;FGF17;PIP5K1BA;ACTN3A;PDGFAA;GSNB
Oxytocin signaling pathwayOXT;EEF2K;PIK3CB;RYR1;ELK1;CCND1;CAMK2G;NFATC1;CAMK2B
Pancreatic secretionSLC4A4;RAB27B;ATP1A2;PLA2G12A;CPA3;PNLIP;KCNQ1;BST1;PLCB2
Bacterial invasion of epithelial cellsSHC3;CLTC;SEPT11;ELMO2;ARPC1A;CTNNA3;SRC;BCAR1;PIK3CG
Pathogenic Escherichia coli infectionPRKCA;ROCK1;EZR;TUBA1C;CDH1;KRT18;TUBA1B;WASL;TUBA3D
PertussisCALM3;IRF1;MAPK1;CASP7;ITGA5;IRF3;GNAI1;AMCF-II;TICAM2
TuberculosisCALM1;FCGR3;NFYA;Ifna11;Il23a; Il12b;PPP3R2;Casp3;CLEC7A;LSP1
Pathways in cancerTGFA;PTGER2;PPARD;IGF1R;LPAR2;CCND1;CUL2;PIK3CB;PIK3CD
Viral carcinogenesisRANBP1;HNRNPK;HLA-E;REL;RB1;STAT5B;KRAS;EP300;HDAC11
Proteoglycans in cancerTNF;ITGB5;RRAS;ITGA2;SLC9A1;SOS1;KRAS;RAC1;ITGAV
MicroRNAs in cancerTP53;ZFPM2;PRKCB;NRAS;DDIT4;NOTCH3;PLCG2;VIM;ABL1
Colorectal cancerMAPK8;KRAS;RAC3;TGFBR1;MAPK1;PIK3R1;MAPK10;TP53;MSH6

RHOA has several biochemical functions, for example, GDP binding, GTP binding, GTPase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RHOA itself. We selected most functions RHOA had, and list some proteins which have the same functions with RHOA. You can find most of the proteins on our site.

Function Related Protein
GDP bindingRAB9A;RAB40C;PIGC;IIGP1;RAB3B;SRP54A;ARL8B;SEPT12;ARL3
GTP bindingTRIM23;SEPT4A;DNM3A;RND1;GCH1;GNA14;GNAS;RABL2B;RAB4B
GTPase activityRAB33B;RAB3C;DNM3A;RAB42B;RAB3D;TUBA1B;RAB18B;TUBA8;GTPBP2
Rho GDP-dissociation inhibitor bindingRHOA;RAC1
myosin bindingTRIM32;VETZ;ARFGEF2;KIRREL;SMYD1B;ACTC1;ARFGEF1;ACTA1;USH2A
protein bindingACYP2;PSMA7;TMEM132D;BAHD1;EFS;RBBP8;HPS6;FAM109A;SKP1
protein domain specific bindingWNT5A;STXBP1;CNTLN;HIST1H4A;EZR;CASP2;GUSB;TBL1X;RARA

RHOA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RHOA here. Most of them are supplied by our site. Hope this information will be useful for your research of RHOA.

RTKN; ARHGDIA; DAAM1; ARHGEF11

Chinestra, P; Olichon, A; et al. Generation of a Single Chain Antibody Variable Fragment (scFv) to Sense Selectively RhoB Activation. PLOS ONE 9:-(2014).
Fichter, CD; Gudernatsch, V; et al. ErbB targeting inhibitors repress cell migration of esophageal squamous cell carcinoma and adenocarcinoma cells by distinct signaling pathways. JOURNAL OF MOLECULAR MEDICINE-JMM 92:1209-1223(2014).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
Is RHOA protein involved in the regulation of blood pressure? 10/26/2021

Yes, RHOA is involved in the regulation of vascular smooth muscle contraction and blood pressure.

What are the potential applications of RHOA inhibitors in cancer therapy? 10/03/2018

RHOA inhibitors may be used to target the metastatic potential of cancer cells and inhibit their ability to spread to other tissues.

Can RHOA inhibitors be used as potential treatments for cardiovascular diseases? 08/02/2018

Yes, RHOA inhibitors may have the potential to be used in the treatment of cardiovascular diseases by targeting vascular smooth muscle contraction.

How is RHOA involved in neurological disorders? 06/24/2017

RHOA has been implicated in the pathogenesis of neurological disorders such as Alzheimer's disease and Parkinson's disease.

Are there any clinical trials investigating the use of RHOA inhibitors in neurological disorders? 01/28/2016

There is emerging research exploring the potential of RHOA inhibitors as a therapeutic approach for neurological disorders.

Customer Reviews (3)

Write a review
Reviews
03/04/2021

    Its reliability and versatility make it an essential tool for investigating RHOA protein's expression, function, and structural characteristics.

    01/03/2020

      The use of RHOA protein in this technique allows researchers to explore the intricate three-dimensional structure of the protein at a molecular level.

      12/21/2018

        RHOA protein is highly recommended for researchers due to its excellent performance in WB experiments and its utility in protein electron microscopy structure analysis.

        Ask a Question for All RHOA Products

        Required fields are marked with *

        My Review for All RHOA Products

        Required fields are marked with *

        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends