RPL7 Protein, ribosomal protein L7

RPL7

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RPL7

Official Full Name ribosomal protein L7
Background Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L30P family of ribosomal proteins. It contains an N-terminal basic region-leucine zipper (BZIP)-like domain and the RNP consensus submotif RNP2. In vitro the BZIP-like domain mediates homodimerization and stable binding to DNA and RNA, with a preference for 28S rRNA and mRNA. The protein can inhibit cell-free translation of mRNAs, suggesting that it plays a regulatory role in the translation apparatus. It is located in the cytoplasm. The protein has been shown to be an autoantigen in patients with systemic autoimmune diseases, such as systemic lupus erythematosus. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Synonyms RPL7; ribosomal protein L7; 60S ribosomal protein L7; humL7 1; L7; RL7_HUMAN; RPL 7; Rpl7a; Surf 3; OTTHUMP00000166002; OTTHUMP00000166003; OTTHUMP00000166004; OTTHUMP00000166005; humL7-1
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • His
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RPL7-31336TH Recombinant Human RPL7, His-tagged E.coli His
    Mouse RPL7-14447M Recombinant Mouse RPL7 Protein Mammalian Cell His
    Cynomolgus Monkey RPL7-882C Recombinant Cynomolgus RPL7 Protein, His-tagged Mammalian Cell His
    Chicken RPL7-1489C Recombinant Chicken RPL7 Mammalian Cell His
    Zebrafish RPL7-12709Z Recombinant Zebrafish RPL7 Mammalian Cell His

    RPL7 involved in several pathways and played different roles in them. We selected most pathways RPL7 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPL7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ribosome RPL22L1; RPL15; MRPL3; RPL27; RPL18A; MRPL13; RPL6; RPS4X; RPL35A; RPL3L

    RPL7 has several biochemical functions, for example, DNA binding, RNA binding, mRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RPL7 itself. We selected most functions RPL7 had, and list some proteins which have the same functions with RPL7. You can find most of the proteins on our site.

    Function Related Protein
    DNA binding ZKSCAN14; POU3F2B; HIST1H4E; IRX2A; POU6F2; NR4A2B; TOP1; ING2; ZEB1B; HOXD9A
    RNA binding RBM15B; RPL7; KHDRBS1B; PUSL1; RTCD1; RBM14; ARHGEF28; RPL13; EIF4E2RS1; RBM4B
    mRNA binding RBM8A; THOC2; TDRD7; RPS13; PAIP2; PIWIL1; RPS3; CPSF5; ELAVL1; EIF4A1
    poly(A) RNA binding ETF1; OASL1; CDC5L; EIF4A2; RPS16; CSTF1; EIF4H; C14orf166; OASL; U2AF2
    protein binding SH3BP4; CLK4; ICAM3; OLR1; TMED10; GNB5; SCARB2; SPG21; VAMP8; PRKD3
    protein homodimerization activity NKX2-5; GSTM1; PYGL; PPP2R4; USF2; GTF2A2; LGALS6; BMPR1A; KCNK9; KLRB1B
    structural constituent of ribosome MRPS15; RPS4Y1; MRPL47; MRPL52; MRPL46; RPL5; MRPS12; RPS14; MRPL13; MRPL55

    RPL7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPL7 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPL7.

    IPO5; NEDD8; ESR1; ESR2; ACTB; RAN; NFKB2; RELA; MAP3K1; NFKBIB; USP38; MAP3K14; TBK1; NR4A1

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