• Official Full Name
  • syndecan binding protein (syntenin) 2
  • Background
  • The protein encoded by this gene contains two class II PDZ domains. PDZ domains facilitate protein-protein interactions by binding to the cytoplasmic C-terminus of transmembrane proteins, and PDZ-containing proteins mediate cell signaling and the organization of protein complexes. The encoded protein binds to phosphatidylinositol 4, 5-bisphosphate (PIP2) and plays a role in nuclear PIP2 organization and cell division. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Read-through transcription also exists between this gene and the upstream FKBP1A (FK506 binding protein 1A, 12kDa) gene, as represented in GeneID:100528031.
  • Synonyms
  • SDCBP2; syndecan binding protein (syntenin) 2; syntenin-2; SITAC18; ST 2; MDA9; Melanoma differentiation associated gene 9; Pro TGF alpha cytoplasmic domain interacting protein 18; Syndecan binding protein 2; OTTHUMP00000029961; OTTHUMP00000029962; OTTHUMP00000029963; OTTHUMP00000029964; ST-2; SITAC
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human SDCBP2
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SDCBP2, His-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human syndecan binding protein (syntenin) 2, His-tagged
Source (Host):Species:Human
Product nameRecombinant Human SDCBP2 293 Cell Lysate

Protein Function

SDCBP2 has several biochemical functions, for example, protein C-terminus binding, protein binding, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SDCBP2 itself. We selected most functions SDCBP2 had, and list some proteins which have the same functions with SDCBP2. You can find most of the proteins on our site.
Related Protein
Function protein C-terminus binding
Related Protein ABL1; DAB2; CACNA1B; VAMP2; CTGF; NCF2; CEP120; PICK1; STIP1; SIRT1
Function protein binding
Related Protein ZNF177; METTL9; MYO5B; PRNP; CCDC60; GOLGA8G; BBS9; TRMT112; FANCI; LIMA1
Function protein heterodimerization activity
Related Protein MEF2A; LIMK2; ATF4; ANO2; P4HB; UGT1A6; NFKB1; ZHX1; RARA; DMRTA2
Function protein homodimerization activity
Related Protein CADM1A; USH2A; GYS2; RAB11FIP2; MAP3K9; KLHL7; RBM11; PVR; PRTFDC1; PARK7

Interacting Protein

SDCBP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SDCBP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SDCBP2.