SEC23A
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Official Full Name
Sec23 homolog A (S. cerevisiae)
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Overview
The protein encoded by this gene is a member of the SEC23 subfamily of the SEC23/SEC24 family. It is part of a protein complex and found in the ribosome-free transitional face of the endoplasmic reticulum (ER) and associated vesicles. This protein has similarity to yeast Sec23p component of COPII. COPII is the coat protein complex responsible for vesicle budding from the ER. The encoded protein is suggested to play a role in the ER-Golgi protein trafficking. [provided by RefSeq, Jul 2008] -
Synonyms
SEC23A; Sec23 homolog A (S. cerevisiae); CLSD; protein transport protein Sec23A; SEC23-related protein A;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
SEC23A involved in several pathways and played different roles in them. We selected most pathways SEC23A participated on our site, such as Adaptive Immune System, Antigen Presentation: Folding, assembly and peptide loading of class I MHC, Asparagine N-linked glycosylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEC23A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Adaptive Immune System | SEC24A;MAP3K8;MGC174857;ASB18;CD300LB;BLK;KIF4;FGF20A;HCST |
| Antigen Presentation: Folding, assembly and peptide loading of class I MHC | SEC24A;ERAP2;ERAP1;B2ML;SEC23A |
| Asparagine N-linked glycosylation | ST8SIA2;TRAPPC5;TRAPPC6B;PPP6R1;DAD1;SCFD1;NEU4;TRAPPC10;TRAPPC2 |
| COPII (Coat Protein 2) Mediated Vesicle Transport | NAPAA;TMED10;TRAPPC2L;TRAPPC5;CTSC;AREG;CSNK1D;PPP6R1;NSFB |
| Cargo concentration in the ER | CNIH;MIA3;CTSZ;SERPINA1L;SEC24A;CTAGE5;MCFD2;TMED10;CNIH3 |
| Class I MHC mediated antigen processing & | TRIM69;ASB17;SEC24A;RNF111;TRIM39;PJA1;UFL1;TRIM41;CD207 |
| presentation | CMTM2A;SPSB1;TRIM69;LRSAM1;ASB17;RNF220;SEC61B;CYBA;ASB11 |
| ER to Golgi Anterograde Transport | PPP6C;TMED2;AREG;BET1;CTSC;TRAPPC1;TRAPPC6BL;TRAPPC9;TMED10 |
| Immune System | IL1RN;IgG3;BAIAP2;ARIH1;CD300LD;TRIM2;DEFB119;GBP5;OSCAR |
SEC23A has several biochemical functions, for example, protein binding, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEC23A itself. We selected most functions SEC23A had, and list some proteins which have the same functions with SEC23A. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein binding | FAM110A;WFIKKN1;KLF11;APTX;FEM1C;HFE2;C1orf94;HHIPL2;OTUB2 |
| zinc ion binding | RNF43;ADH5;BFAR;LIMS3L;MUL1B;CALB1;PRICKLE1B;NEURL1AA;LMO7B |
SEC23A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEC23A here. Most of them are supplied by our site. Hope this information will be useful for your research of SEC23A.
SEC24C; CDK16; SEC31A; SEC13; SEC24D; CDK18; SEC24B; KDELR1; HLA-B; GALNT1; TMED2; NDRG1
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