|Official Full Name||SH2 domain containing 3C|
|Background||This gene encodes an adaptor protein and member of a cytoplasmic protein family involved in cell migration. The encoded protein contains a putative Src homology 2 (SH2) domain and guanine nucleotide exchange factor-like domain which allows this signaling protein to form a complex with scaffolding protein Crk-associated substrate. Multiple transcript variants encoding different isoforms have been found for this gene.|
|Synonyms||SH2D3C; SH2 domain containing 3C; SH2 domain-containing protein 3C; NSP3; novel SH2-containing protein 3; CHAT; PRO34088; FLJ39664|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
SH2D3C involved in several pathways and played different roles in them. We selected most pathways SH2D3C participated on our site, such as EGFR1 Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SH2D3C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|EGFR1 Signaling Pathway||TNK2; RALBA; CRKL; RGS5B; EPS8; ZFP259; WNK1; GRB10; DNM1; RBBP7|
SH2D3C has several biochemical functions, for example, SH3/SH2 adaptor activity, guanyl-nucleotide exchange factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SH2D3C itself. We selected most functions SH2D3C had, and list some proteins which have the same functions with SH2D3C. You can find most of the proteins on our site.
|SH3/SH2 adaptor activity||STAM; ITSN2; SOCS2; SH2B2; IRS4; STAP1; SH2D1A; GRB14; PTPN11; SH3BGRL|
|guanyl-nucleotide exchange factor activity||RASGEF1C; SERGEF; SBF1; RABIF; VAV3; RASGRP2; FGD1; RASGRP3; VAV1; TRIO|
|protein binding||SGTA; IL17RA; BNIP3; PTGIS; PPIL3; RAPGEF3; PMM1; RHOT2; PSMG2; CRCT1|
SH2D3C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SH2D3C here. Most of them are supplied by our site. Hope this information will be useful for your research of SH2D3C.
MET; AR; KIT; EFS; EGFR