SH2D3C Protein, SH2 domain containing 3C


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Official Full Name SH2 domain containing 3C
Background This gene encodes an adaptor protein and member of a cytoplasmic protein family involved in cell migration. The encoded protein contains a putative Src homology 2 (SH2) domain and guanine nucleotide exchange factor-like domain which allows this signaling protein to form a complex with scaffolding protein Crk-associated substrate. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms SH2D3C; SH2 domain containing 3C; SH2 domain-containing protein 3C; NSP3; novel SH2-containing protein 3; CHAT; PRO34088; FLJ39664
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SH2D3C-1877HCL Recombinant Human SH2D3C 293 Cell Lysate HEK293 N/A
    Human SH2D3C-2641H Recombinant Human SH2D3C, GST-tagged E.coli GST
    Mouse SH2D3C-15058M Recombinant Mouse SH2D3C Protein Mammalian Cell His

    SH2D3C involved in several pathways and played different roles in them. We selected most pathways SH2D3C participated on our site, such as EGFR1 Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SH2D3C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    EGFR1 Signaling Pathway TNK2; RALBA; CRKL; RGS5B; EPS8; ZFP259; WNK1; GRB10; DNM1; RBBP7

    SH2D3C has several biochemical functions, for example, SH3/SH2 adaptor activity, guanyl-nucleotide exchange factor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SH2D3C itself. We selected most functions SH2D3C had, and list some proteins which have the same functions with SH2D3C. You can find most of the proteins on our site.

    Function Related Protein
    SH3/SH2 adaptor activity STAM; ITSN2; SOCS2; SH2B2; IRS4; STAP1; SH2D1A; GRB14; PTPN11; SH3BGRL
    guanyl-nucleotide exchange factor activity RASGEF1C; SERGEF; SBF1; RABIF; VAV3; RASGRP2; FGD1; RASGRP3; VAV1; TRIO
    protein binding SGTA; IL17RA; BNIP3; PTGIS; PPIL3; RAPGEF3; PMM1; RHOT2; PSMG2; CRCT1

    SH2D3C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SH2D3C here. Most of them are supplied by our site. Hope this information will be useful for your research of SH2D3C.


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