|Official Full Name||Src homology 2 domain containing adaptor protein B|
|Background||SH2 domain-containing adapter protein B is a protein that in humans is encoded by the SHB gene.|
|Synonyms||SHB; Src homology 2 domain containing adaptor protein B; SHB (Src homology 2 domain containing) adaptor protein B , SHB adaptor protein (a Src homology 2 protein); SH2 domain-containing adapter protein B; SHB adaptor protein (a Src homology 2 protein); S|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
SHB involved in several pathways and played different roles in them. We selected most pathways SHB participated on our site, such as Axon guidance, Developmental Biology, EPH-Ephrin signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Axon guidance||PTK2; RASA1; SEMA3D; GFRA2; SPRED2; NRP1A; CDK5; CAP1; COL6A2; RASGEF1A|
|Developmental Biology||MED29; AP2B1; FOXH1; NRG3; DOCK1; PHB; SPNA1; EFNA1B; CACNG3; EGR2|
|EPH-Ephrin signaling||EFNB1; ARPC1B; MYL12A; EPHA4A; EFNA1; ARHGEF28; EFNB3B; AP2A2; EFNA5; EPHA2|
|EPHA-mediated growth cone collapse||EFNA3B; EFNA1B; EFNA5; EPHA10; SHB; EFNA1; EPHA4A; KDR; EFNA2A; EPHA2|
|IL-2 Signaling Pathway||SHB; CD53; CISH; ITM2BA; NMI|
|Signal Transduction||IFT52; CDC42EP3; DHRS4; GUCA1E; TAS2R16; ARHGAP40; NOTUM; THBS3B; NRP2B; APOM|
|Signaling by VEGF||NRP2A; AXL; NRP2; NRP2B; SHB; DSCAMA; JUPA|
|T Cell Receptor Signaling Pathway||GRAP2; NFATC3; MAPK9; PIK3CA; Il2; CBLB; PIK3R2; NCK2; OXSR1A; CD8B|
SHB has several biochemical functions, for example, SH3/SH2 adaptor activity, glycoprotein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SHB itself. We selected most functions SHB had, and list some proteins which have the same functions with SHB. You can find most of the proteins on our site.
|SH3/SH2 adaptor activity||SLA2; SH2B2; PTPN11; STAM; FCRL2; STAP1; NCK1; SHB; CD28; SKAP1|
|glycoprotein binding||IGF2R; FBXO2; FBXO6; ERBB2; CALR; BMPR1A; ITGAM; VWF; CSNK1D; CNTN2|
SHB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHB here. Most of them are supplied by our site. Hope this information will be useful for your research of SHB.