SHC2 Protein, SHC (Src homology 2 domain containing) transforming protein 2


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Official Full Name SHC (Src homology 2 domain containing) transforming protein 2
Background SHC-transforming protein 2 is a protein that in humans is encoded by the SHC2 gene, SHC2 has been shown to interact with Kinase insert domain receptor.
Synonyms SHC2; SHC (Src homology 2 domain containing) transforming protein 2; SHC-transforming protein 2; neuronal Shc adaptor homolog; SCK; SHCB; SLI; Protein Sck; SH2 domain protein C2; SHC transforming protein 2; Src homology 2 domain containing transforming protein C2; SHC-transforming protein B; src homology 2 domain-containing-transforming protein C2
    • Species :
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • Mammalian Cell
    • Tag :
    • His
    • T7
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse SHC2-15091M Recombinant Mouse SHC2 Protein Mammalian Cell His
    Mouse Shc2-1745M Recombinant Mouse Shc2 protein, His & T7-tagged E.coli His/T7
    Rat SHC2-5390R Recombinant Rat SHC2 Protein Mammalian Cell His
    Zebrafish SHC2-4062Z Recombinant Zebrafish SHC2 Mammalian Cell His

    SHC2 involved in several pathways and played different roles in them. We selected most pathways SHC2 participated on our site, such as ErbB signaling pathway, Ras signaling pathway, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    ErbB signaling pathway CAMK2D1; PAK6B; MTOR; NRG2B; EREG; RPS6KB1; SHC2; MYCB; GRB2B; MAP2K2A
    Ras signaling pathway FGF22; PTPN11; GRIN1; RGL2; GNGT2; FGFR4; GNG2; FLT4; PLA2G5; INSR
    Chemokine signaling pathway CXCL8; CCL16; PXN; GNG2; ROCK2; CXCR2; AKT1; SHC4; MAPK3; ARRB2
    Phospholipase D signaling pathway F2R; GNAS; PLCG2; PLA2G4D; PIK3R1; PIK3CD; LPAR3; DGKZ; PIK3R5; MAP2K1
    Focal adhesion PPP1CAA; RAPGEF1; BCL2A; COL5A2; ACTB2; SOS1; AKT3A; LAMB3; CAPN2B; GRB2B
    Natural killer cell mediated cytotoxicity PIK3CG; RAET1D; IFNGR1; IFNAR1; PRKCG; PIK3R3; RAET1L; KIR2DS5; KIR3DL2; RAC3
    Neurotrophin signaling pathway MAPK7; SHC1; IKBKB; NTF4; BAD; NTRK2; NGFRAP1; ZFP110; NTRK1; PIK3R5
    Insulin signaling pathway PYGM; PRKAG3B; IRS4; TRIP10; CALM2B; TRIP10A; PIK3R3; GSK3AA; EIF4E1C; PIK3CG
    Estrogen signaling pathway GABBR1; GNAI1; PIK3CA; HSPA6; KRAS; ATF6B; GNAI2; ATF4; PIK3R3; PIK3CG
    Prolactin signaling pathway GALT; PRL; KRAS; MAPK10; AKT1; PIK3CB; MAPK1; ESR2; MAPK11; TNFSF11
    Alcoholism H3F3C; HIST1H2AK; GM6026; HDAC1; BRAF; H2BFWT; CREB3L4; CALM2; HIST1H2BB; GNG10
    Bacterial invasion of epithelial cells ARPC1B; PXN; SEPT6; DOCK1; CD2AP; SHC4; SEPT12; CDC42; RHOG; CDH1
    Glioma CALM4; TP53; MAPK1; PIK3R3; PRKCA; SOS1; PIK3CB; MAP2K1; PIK3R2; MAP2K2
    Chronic myeloid leukemia PIK3R2; SOS1; PIK3R5; NFKBIA; KRAS; CCND1; PIK3CG; AKT1; GAB2; RB1

    SHC2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SHC2 itself. We selected most functions SHC2 had, and list some proteins which have the same functions with SHC2. You can find most of the proteins on our site.

    Function Related Protein

    SHC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SHC2.


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