|Official Full Name||SHC (Src homology 2 domain containing) transforming protein 2|
|Background||SHC-transforming protein 2 is a protein that in humans is encoded by the SHC2 gene, SHC2 has been shown to interact with Kinase insert domain receptor.|
|Synonyms||SHC2; SHC (Src homology 2 domain containing) transforming protein 2; SHC-transforming protein 2; neuronal Shc adaptor homolog; SCK; SHCB; SLI; Protein Sck; SH2 domain protein C2; SHC transforming protein 2; Src homology 2 domain containing transforming protein C2; SHC-transforming protein B; src homology 2 domain-containing-transforming protein C2|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
SHC2 involved in several pathways and played different roles in them. We selected most pathways SHC2 participated on our site, such as ErbB signaling pathway, Ras signaling pathway, Chemokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SHC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|ErbB signaling pathway||CAMK2D1; PAK6B; MTOR; NRG2B; EREG; RPS6KB1; SHC2; MYCB; GRB2B; MAP2K2A|
|Ras signaling pathway||FGF22; PTPN11; GRIN1; RGL2; GNGT2; FGFR4; GNG2; FLT4; PLA2G5; INSR|
|Chemokine signaling pathway||CXCL8; CCL16; PXN; GNG2; ROCK2; CXCR2; AKT1; SHC4; MAPK3; ARRB2|
|Phospholipase D signaling pathway||F2R; GNAS; PLCG2; PLA2G4D; PIK3R1; PIK3CD; LPAR3; DGKZ; PIK3R5; MAP2K1|
|VEGF signaling pathway||HRAS; MAP2K2A; MAPK12B; RAC3; PTGS2A; PPP3CB; PRKCBB; PRKCBA; RAC1A; SPHK2|
|Focal adhesion||PPP1CAA; RAPGEF1; BCL2A; COL5A2; ACTB2; SOS1; AKT3A; LAMB3; CAPN2B; GRB2B|
|Natural killer cell mediated cytotoxicity||PIK3CG; RAET1D; IFNGR1; IFNAR1; PRKCG; PIK3R3; RAET1L; KIR2DS5; KIR3DL2; RAC3|
|Neurotrophin signaling pathway||MAPK7; SHC1; IKBKB; NTF4; BAD; NTRK2; NGFRAP1; ZFP110; NTRK1; PIK3R5|
|Insulin signaling pathway||PYGM; PRKAG3B; IRS4; TRIP10; CALM2B; TRIP10A; PIK3R3; GSK3AA; EIF4E1C; PIK3CG|
|Estrogen signaling pathway||GABBR1; GNAI1; PIK3CA; HSPA6; KRAS; ATF6B; GNAI2; ATF4; PIK3R3; PIK3CG|
|Prolactin signaling pathway||GALT; PRL; KRAS; MAPK10; AKT1; PIK3CB; MAPK1; ESR2; MAPK11; TNFSF11|
|Alcoholism||H3F3C; HIST1H2AK; GM6026; HDAC1; BRAF; H2BFWT; CREB3L4; CALM2; HIST1H2BB; GNG10|
|Bacterial invasion of epithelial cells||ARPC1B; PXN; SEPT6; DOCK1; CD2AP; SHC4; SEPT12; CDC42; RHOG; CDH1|
|Glioma||CALM4; TP53; MAPK1; PIK3R3; PRKCA; SOS1; PIK3CB; MAP2K1; PIK3R2; MAP2K2|
|Chronic myeloid leukemia||PIK3R2; SOS1; PIK3R5; NFKBIA; KRAS; CCND1; PIK3CG; AKT1; GAB2; RB1|
SHC2 has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by SHC2 itself. We selected most functions SHC2 had, and list some proteins which have the same functions with SHC2. You can find most of the proteins on our site.
SHC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SHC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of SHC2.