slc22a7
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  • Official Full Name
  • solute carrier family 22 (organic anion transporter), member 7
  • Background
  • The protein encoded by this gene is involved in the sodium-independent transport and excretion of organic anions, some of which are potentially toxic. The encoded protein is an integral membrane protein and appears to be localized to the basolateral membrane of the kidney. Alternatively spliced transcript variants encoding different isoforms have been described.
  • Synonyms
  • SLC22A7; solute carrier family 22 (organic anion transporter), member 7; solute carrier family 22 member 7; NLT; OAT2; hOAT2; novel liver transporter; liver-specific transporter; organic anion transporter 2; MGC24091; MGC45202
Cat.#:SLC22A7-5461RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SLC22A7 Protein
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Cat.#:SLC22A7-4305CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SLC22A7
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Cat.#:SLC22A7-1791HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SLC22A7 293 Cell Lysate
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Involved Pathway

SLC22A7 involved in several pathways and played different roles in them. We selected most pathways SLC22A7 participated on our site, such as Bile secretion, Fluoropyrimidine Activity, Organic anion transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC22A7 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Bile secretion
KCNN2; SLCO1B3; ABCG8; SLC51B; ATP1B3; ABCB1A; ADCY9; PRKACB; Car2; SLC22A8
Fluoropyrimidine Activity
DPYS; SLC22A7; UPP2; TYMP; DHFR; DPYD; CES1
Organic anion transport
SLC22A7B.1; SLC22A7A; SLC22A7; SLC22A12; SLC22A6
Organic cation/anion/zwitterion transport
SLC22A7B.1; SLC22A18; SLC22A7; SLC22A6; SLC22A12; SLC22A7A; SLC22A16; SLC22A15
SLC-mediated transmembrane transport
SLC22A16; SLC26A6L; SLC2A6; SLC36A2; SLC6A11; SLC43A1A; SLC12A5B; SLC22A18; SLC30A6; SLC6A6
Transmembrane transport of small molecules
SLC38A4; FXYD3; SLC13A2; ANKHA; LCN9; SLC22A6; SLC39A8; AQP10B; CLCN7; FKBP1B
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
SLC39A3; SLC41A1; SLC5A11; SLC22A7; SLC6A20B; SLC13A5; SLC22A12; SLC30A2; SLC6A19B; SLC22A16

Protein Function

SLC22A7 has several biochemical functions, for example, protein binding, sodium-independent organic anion transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC22A7 itself. We selected most functions SLC22A7 had, and list some proteins which have the same functions with SLC22A7. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein CHID1; MDM4; AMBP; BNIP1; ELOVL6; THRAP3; DPEP1; KCND3; ZCCHC7; CRYBB3
Function sodium-independent organic anion transmembrane transporter activity
Related Protein SLCO2B1; SLCO1F4; SLCO1C1; SLCO1F1; SLCO1A6; SLC22A7; SLCO1B2; SLCO4C1; SLCO4A1; SLC22A24

Interacting Protein

SLC22A7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC22A7 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC22A7.
RAPGEF4; p27958-pro_0000037566

SLC22A7 Related Articles

Ljubojevic, M; Balen, D; et al. Renal expression of organic anion transporter OAT2 in rats and mice is regulated by sex hormones. AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY 292:F361-F372(2007).