ssrp1
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  • Official Full Name
  • structure specific recognition protein 1
  • Background
  • SSRP1 is a nuclear protein and a component of the FACT complex (facilitates chromatin transcription). The FACT complex is composed of the SUPT16H (FACT140) and the SSRP1 FACTp80 proteins. This complex interacts with nucleosomes and histone H2A/H2B dimers
  • Synonyms
  • SSRP1; structure specific recognition protein 1; FACT complex subunit SSRP1; facilitates chromatin remodeling 80 kDa subunit; FACT80; hSSRP1; FACTp80; cisplatin-DNA SSRP; FACT 80 kDa subunit; high mobility group box; structure-specific recognition protein
Cat.#:SSRP1-29276THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SSRP1, His-tagged
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Cat.#:SSRP1-638HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SSRP1 Protein, His-tagged
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Cat.#:SSRP1-5758RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SSRP1 Protein
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Cat.#:SSRP1-4492RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SSRP1 Protein, His-tagged
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Cat.#:SSRP1-1250CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SSRP1
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Cat.#:SSRP1-1456HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human SSRP1 293 Cell Lysate
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Involved Pathway

SSRP1 involved in several pathways and played different roles in them. We selected most pathways SSRP1 participated on our site, such as Disease, Formation of HIV elongation complex in the absence of HIV Tat, Formation of HIV-1 elongation complex containing HIV-1 Tat, which may be useful for your reference. Also, other proteins which involved in the same pathway with SSRP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Disease
RDBP; ACAN; TIRAP; CDK8; FDX1L; MIB1; PRELP; OS9; SUPT5H; LRRFIP1
Formation of HIV elongation complex in the absence of HIV Tat
TCEB3; SUPT4H1; WHSC2; SSRP1; CDK9; RDBP; CTDP1; TCEA1; PSTPIP2; SUPT5H
Formation of HIV-1 elongation complex containing HIV-1 Tat
SUPT5H; WHSC2; CDK9; ELL; SUPT4H1; COBRA1; RDBP; TCEA1; CTDP1; TCEB3
Formation of RNA Pol II elongation complex
TCEA1; CCNT2B; SSRP1A; NELFE; SUPT5H; WHSC2; SUPT16H; CTDP1; ELL; RDBP
Gene Expression
KRBA1; ZNF192; NRBF2B; NXF1; TRMT5; ZKSCAN5; ZNF354A; HNRNPUL1; GTF3C5; GATAD2B
HIV Infection
APOBEC3G; CDK9; CHMP4B; ELL; CHMP4C; PSTPIP2; PPIAL4A; PSIP1; RCC1; TAF1L
HIV Life Cycle
PSIP1; TAF1L; CHMP4C; NMT2; CDK9; PSTPIP2; ELL; SSRP1; NMT1; PDCD6IP
HIV Transcription Elongation
TCEB3; SSRP1

Protein Function

SSRP1 has several biochemical functions, for example, DNA binding, chromatin binding, poly(A) RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SSRP1 itself. We selected most functions SSRP1 had, and list some proteins which have the same functions with SSRP1. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein POU4F2; MAFBA; TET2; LASS5; CHD6; DDX3X; DNA2; MYEF2; TSHZ3; PBX3B
Function chromatin binding
Related Protein GATA6; POU2F1; TDRD3; CEBPB; PRKAA1; RFX4; NIPBL; CBX1; GATA3; SUV39H1
Function poly(A) RNA binding
Related Protein KCTD12; AATF; GTL3; ZFP326; CSTF2T; GSPT2; LTA4H; DDX54; C14orf166; SF3A3
Function protein binding
Related Protein OCIAD1; CATSPERB; C19orf46; TRMT1; CUEDC2; MESDC1; PPP2CB; TAF8; C11orf65; METTL9

Interacting Protein

SSRP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SSRP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SSRP1.
MCM4; CSNK2A1; SUPT16H; VCAM1; HDGF; CD3EAP