|Official Full Name||sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1|
|Background||Dehydroepiandrosterone sulfate or DHEA sulfate is a metabolite of dehydroepiandrosterone (DHEA) produced by the addition of a sulfate group, catalyzed by the sulfotransferase enzymes SULT1A1 and SULT1E1, which also produce estrone sulfate from estrone. DHEA sulfate can also be back-converted to DHEA through the action of steroid sulfatase.In the zona reticularis layer of the adrenal cortex, DHEA-sulfate is generated by SULT2A1. This layer of the adrenal cortex is thought to be the primary source of serum DHEA-sulfate. DHEA sulfate levels decline as a person ages as the reticularis layer diminishes in size.|
|Synonyms||Alcohol/hydroxysteroid sulfotransferase; Bile salt sulfotranasferase 2A1; Bile salt sulfotransferase; Dehydroepiandrosterone sulfotransferase; DHEA ST; DHEA-ST; DHEAS; EC 188.8.131.52; HST; hSTa; Hydroxysteroid Sulfotransferase; ST2; ST2A1; ST2A1_HUMAN; ST2A3; STD Sulfotransferase 2A1; Sulfotransferase family cytosolic 2A dehydroepiandrosterone (DHEA) preferring member 1; Sult2a1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
SULT2A1 involved in several pathways and played different roles in them. We selected most pathways SULT2A1 participated on our site, such as Metabolism of xenobiotics by cytochrome P, Bile secretion, Chemical carcinogenesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with SULT2A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Metabolism of xenobiotics by cytochrome P||UGT1A2; AKR7A3; GSTM; ALDH3B2; GSTA1; MGST1.1; GSTA2; UGT1A7C; CBR1L; DHDHL|
|Bile secretion||SLCO1A4; ADCY3; ATP1A3; PRKACA; NR0B2; ABCB11; LDLR; OSTB; SLCO1B2; ABCB4|
|Chemical carcinogenesis||UGT1A2; CYP2E1; CYP3A43; UGT1A6; UGT2A1; EPHX1; GSTA2; ALDH3B2; ADH2-2; SULT1A3|
SULT2A1 has several biochemical functions, for example, bile-salt sulfotransferase activity, protein binding, sulfotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SULT2A1 itself. We selected most functions SULT2A1 had, and list some proteins which have the same functions with SULT2A1. You can find most of the proteins on our site.
|bile-salt sulfotransferase activity||SULT2A1|
|protein binding||UBE2L3; PDZD3; SLC35A2; ODF1; PRDM4; GAPDH; GPRIN2; CDKN2C; FASTKD5; OSGIN1|
|sulfotransferase activity||SULT1A2; CHST3A; Sult2a2; SULT5A1; CHST2; SULT1C2; HS6ST1A; SULT6B1; HS3ST1L1; HS3ST3B1A|
SULT2A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SULT2A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SULT2A1.
SULT1B1; STAT3; PRDX4; STK3; TMX1