smad9
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  • Official Full Name
  • SMAD family member 9
  • Background
  • The protein encoded by this gene is a member of the SMAD family, which transduces signals from TGF-beta family members. The encoded protein is activated by bone morphogenetic proteins and interacts with SMAD4. Two transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • SMAD9; SMAD family member 9; MAD, mothers against decapentaplegic homolog 9 (Drosophila) , MADH6, MADH9, SMAD, mothers against DPP homolog 9 (Drosophila); mothers against decapentaplegic homolog 9; MAD homolog 9; MADH6; Mothers against decapentaplegic; SMAD 9; SMAD, mothers against DPP homolog 9 (Drosophila); SMAD8A; SMAD8B; SMAD, mothers against DPP homolog 9; Mothers against decapentaplegic, drosophila, homolog of, 9; MADH9; SMAD8
Cat.#:SMAD9-1914HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human SMAD9 Protein, MYC/DDK-tagged
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Cat.#:SMAD9-302HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SMAD9 Protein, His/GST-tagged
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Cat.#:SMAD9-234HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SMAD9, GST-tagged
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Cat.#:SMAD9-2802HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SMAD9, GST-tagged
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Cat.#:SMAD9-5611RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SMAD9 Protein
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Cat.#:SMAD9-4334RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SMAD9 Protein, His-tagged
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Cat.#:SMAD9-2196CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SMAD9
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Cat.#:SMAD9-1212ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SMAD9
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Cat.#:SMAD9-1645HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SMAD9 cell lysate
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Involved Pathway

SMAD9 involved in several pathways and played different roles in them. We selected most pathways SMAD9 participated on our site, such as TGF-beta signaling pathway, Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with SMAD9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
TGF-beta signaling pathway
IFNG1-2; CUL1; TGFBR1; LFT2; IFNG; TFDP1A; ACVR1; BMPR1AB; CHRD; AMH
Signaling pathways regulating pluripotency of stem cells
WNT2; MEIS1; FZD8; ONECUT1; AXIN2; PIK3R1; FGFR4; RAF1; MYF5; MAPK12

Protein Function

SMAD9 has several biochemical functions, for example, DNA binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SMAD9 itself. We selected most functions SMAD9 had, and list some proteins which have the same functions with SMAD9. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein UNCX4.1; PRDM10; PUF60B; APP; MBD1B; NR6A1; NPAS2; FOXI3A; HOXD3; RCAN1
Function metal ion binding
Related Protein ZFP143; FRRS1; MLL1; ELMSAN1A; ZNF217; NRP1A; FTH1B; TESK1; ZFP41; ZNF410
Function protein binding
Related Protein RNF11; NLRP2; VPS53; LSM11; MYBBP1A; GNB2L1; STOML1; CKS1B; ACTA1; DLL1
Function transcription factor activity, sequence-specific DNA binding
Related Protein MNX1; ZNF232; ZBTB11; PA2G4; ZFP37; NFE2L2; FOXN2B; ZNF789; MKL1; STAT2
Function transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
Related Protein SMAD9; SMAD1; SMAD2; SMAD3

Interacting Protein

SMAD9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SMAD9 here. Most of them are supplied by our site. Hope this information will be useful for your research of SMAD9.
KDM1A; PRMT6; UBA6; MTMR11; EIF3F; PIR; KMT2D; KDM6A; ZEB2; MCM3AP; MAN1A2; LRP5; SF3B1; DKK1; AP2A1; CSH1; FTL; CYP11A1

SMAD9 Related Gene Family

TGF