tas2r13
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  • Official Full Name
  • taste receptor, type 2, member 13
  • Background
  • This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.
  • Synonyms
  • TAS2R13; taste receptor, type 2, member 13; taste receptor type 2 member 13; T2R13; TRB3; Taste receptor, family B, member 3; taste receptor family B member 3
Cat.#:TAS2R13-4620RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey TAS2R13 Protein, His-tagged
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Cat.#:TAS2R13-651HCLTag:N/A
Source (Host):HEK293Species:Human
Product nameRecombinant Human TAS2R13 lysate
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Involved Pathway

TAS2R13 involved in several pathways and played different roles in them. We selected most pathways TAS2R13 participated on our site, such as Class C/3 (Metabotropic glutamate/pheromone receptors), G alpha (i) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAS2R13 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Class C/3 (Metabotropic glutamate/pheromone receptors)
GPRC6A; TAS2R7; TAS2R3; CASR; TAS2R13; TAS2R16
G alpha (i) signalling events
ANXA1A; TAS2R13; OPN1MW; LPAR5A; RLN3A; ADORA1; INSL5; CNR1; POMCB; RGS10
GPCR downstream signaling
ARHGEF1A; PTHRP2; PYYA; CCR8; TAS2R13; CCR6; GCGB; NMS; FPR-RS3; NMU
GPCR ligand binding
CHRM4; NTS; ACKR4; HCAR1-2; INSL5; QRFP; S1PR3; PTH2; OPN1MW; EMR3
Signal Transduction
PYY; SKILB; QRFPR; DLK1; SCUBE2; DNAL4; OPHN1; KREMEN1; TNKS2; INHBAA
Signaling by GPCR
MLN; OXTRL; GAL; KEL; OBSCN; OR2AP1; OR10A5; GNA13B; RGS10; KISS1
Taste transduction
SCNN1G; TAS2R125; TAS2R13; TAS2R140; SCNN1B; TAS2R42; PDE1A; ITPR3; GNB1; TAS2R134

Protein Function

TAS2R13 has several biochemical functions, for example, bitter taste receptor activity, taste receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TAS2R13 itself. We selected most functions TAS2R13 had, and list some proteins which have the same functions with TAS2R13. You can find most of the proteins on our site.
Function
Related Protein
Function bitter taste receptor activity
Related Protein TAS2R144; TAS2R138; TAS2R16; TAS2R121; TAS2R108; TAS2R13; TAS2R140; TAS2R137; TAS2R7; TAS2R118
Function taste receptor activity
Related Protein TAS1R2; GPR120; TAS2R3; TAS2R7; TAS2R136; TAS2R13; TAS2R138; TAS2R137; TAS2R108; TAS1R1

TAS2R13 Related Articles

Allen, AL; McGeary, JE; et al. Polymorphisms in TRPV1 and TAS2Rs Associate with Sensations from Sampled Ethanol. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 38:2550-2560(2014).
Mfuna Endam, L; Filali-Mouhim, A; et al. Genetic variations in taste receptors are associated with chronic rhinosinusitis: a replication study. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY 4:200-206(2014).