TAS2R13 Protein, taste receptor, type 2, member 13


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Official Full Name taste receptor, type 2, member 13
Background This gene product belongs to the family of candidate taste receptors that are members of the G-protein-coupled receptor superfamily. These proteins are specifically expressed in the taste receptor cells of the tongue and palate epithelia. They are organized in the genome in clusters and are genetically linked to loci that influence bitter perception in mice and humans. In functional expression studies, they respond to bitter tastants. This gene maps to the taste receptor gene cluster on chromosome 12p13.
Synonyms TAS2R13; taste receptor, type 2, member 13; taste receptor type 2 member 13; T2R13; TRB3; Taste receptor, family B, member 3; taste receptor family B member 3
    • Species :
    • Human
    • Rhesus Macaque
    • Source :
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TAS2R13-651HCL Recombinant Human TAS2R13 lysate HEK293 N/A
    Rhesus Macaque TAS2R13-4620R Recombinant Rhesus monkey TAS2R13 Protein, His-tagged Mammalian Cell His

    TAS2R13 involved in several pathways and played different roles in them. We selected most pathways TAS2R13 participated on our site, such as Class C/3 (Metabotropic glutamate/pheromone receptors), G alpha (i) signalling events, GPCR downstream signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with TAS2R13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Class C/3 (Metabotropic glutamate/pheromone receptors) TAS2R3; TAS2R7; CASR; TAS2R13; TAS2R16; GPRC6A
    G alpha (i) signalling events PTGDR2; OXER1; LPAR2B; OPN5; RLN3; ANXA1B; ADRA2B; OPN1MW; ANXA1; OPN1LW1
    GPCR downstream signaling PNOC; CCR6; AGTR2; FFAR3; S1PR1; RXFP2; TAC3; TRH; HEBP1; AKAP13
    GPCR ligand binding QRFP; INSL5; AMCF-II; HRH3; CD97; SST; FFAR3; CHRM1; CCL35.1; INSL3
    Signal Transduction GPR37L1; RHOT1A; IQGAP3; RGS7; AMOTL2B; TAS2R3; RNF43; PTGDR2; UCHL5; CIT
    Signaling by GPCR GPR55A; NET1; TAS2R13; OR2AP1; EMR2; OR52J3; PLEKHG2; OXGR1A.2; RGS1; GPR31B
    Taste transduction KCNB1; TAS2R125; GNG3; TAS1R1; TAS2R144; PLCB2; TAS2R138; ASIC2; TAS2R20; TAS2R38

    TAS2R13 has several biochemical functions, for example, bitter taste receptor activity, taste receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TAS2R13 itself. We selected most functions TAS2R13 had, and list some proteins which have the same functions with TAS2R13. You can find most of the proteins on our site.

    Function Related Protein
    bitter taste receptor activity TAS2R7; TAS2R40; TAS2R108; TAS2R120; TAS2R13; TAS2R140; TAS2R16; TAS2R114; TAS2R144; TAS2R138
    taste receptor activity TAS2R140; TAS1R2; TAS2R143; TAS2R137; TAS1R3; O3far1; GPR120; TAS2R13; TAS2R144; TAS2R108

    TAS2R13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TAS2R13 here. Most of them are supplied by our site. Hope this information will be useful for your research of TAS2R13.

    Allen, AL; McGeary, JE; et al. Polymorphisms in TRPV1 and TAS2Rs Associate with Sensations from Sampled Ethanol. ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH 38:2550-2560(2014).
    Mfuna Endam, L; Filali-Mouhim, A; et al. Genetic variations in taste receptors are associated with chronic rhinosinusitis: a replication study. INTERNATIONAL FORUM OF ALLERGY & RHINOLOGY 4:200-206(2014).

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