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TGFB1I1

  • Official Full Name

    transforming growth factor beta 1 induced transcript 1

  • Overview

    This gene encodes a coactivator of the androgen receptor, a transcription factor which is activated by androgen and has a key role in male sexual differentiation. The encoded protein is thought to regulate androgen receptor activity and may have a role to play in the treatment of prostate cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • Synonyms

    TGFB1I1; transforming growth factor beta 1 induced transcript 1; HIC5; ARA55; HIC-5; TSC-5; transforming growth factor beta-1-induced transcript 1 protein; androgen receptor coactivator ARA55; hydrogen peroxide-inducible clone 5 protein; androgen receptor coactivator 55 kDa protein; androgen receptor-associated protein of 55 kDa;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TGFB1I1-1120HCL Recombinant Human TGFB1I1 293 Cell Lysate HEK293 N/A
Human TGFB1I1-6432H Recombinant Human TGFB1I1 Protein (Phe252-Arg390), His tagged E.coli His Phe252-Arg390
Human TGFB1I1-652H Recombinant Human TGFB1I1 Protein, His-tagged E.coli His Phe252~Arg390+RCARTTSTHDAARCAPRVASL
Mouse TGFB1I1-16703M Recombinant Mouse TGFB1I1 Protein Mammalian Cell His
Mouse TGFB1I1-9160M Recombinant Mouse TGFB1I1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Tgfb1i1-6388M Recombinant Mouse Tgfb1i1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse TGFB1I1-9160M-B Recombinant Mouse TGFB1I1 Protein Pre-coupled Magnetic Beads HEK293
Rat TGFB1I1-6036R Recombinant Rat TGFB1I1 Protein Mammalian Cell His
Rat TGFB1I1-5694R Recombinant Rat TGFB1I1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat TGFB1I1-5694R-B Recombinant Rat TGFB1I1 Protein Pre-coupled Magnetic Beads HEK293
Rat Tgfb1i1-653R Recombinant Rat Tgfb1i1 Protein, His-tagged E.coli His Gly256~Gly461
Rhesus Macaque TGFB1I1-4686R Recombinant Rhesus monkey TGFB1I1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque TGFB1I1-4500R Recombinant Rhesus Macaque TGFB1I1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque TGFB1I1-4500R-B Recombinant Rhesus Macaque TGFB1I1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TGFB1I1 Related Articles
  • TGFB1I1 Related Gene Family
  • TGFB1I1 Related Research Area

TGFB1I1 involved in several pathways and played different roles in them. We selected most pathways TGFB1I1 participated on our site, such as Androgen receptor signaling pathway, Coregulation of Androgen receptor activity, Monoamine Transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with TGFB1I1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Androgen receptor signaling pathwayPSMC3IP;KAT5;HTATIP;NCOA2;CREBBP;PIAS3;DAXX;CTNNB2;JUN
Coregulation of Androgen receptor activityPATZ1;PIAS3;SVIL;CTDSP2;PA2G4;KDM3A;NRIP1;TCF4;KDM1A
Monoamine TransportTPH2;HRH3;TGFB1I1;UNC13B;SCAMP2;FBXO32;DBH;SYN1
Serotonin Transporter ActivityTGFB1I1;TPH2;SCAMP2

TGFB1I1 has several biochemical functions, for example, I-SMAD binding, Roundabout binding, androgen receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TGFB1I1 itself. We selected most functions TGFB1I1 had, and list some proteins which have the same functions with TGFB1I1. You can find most of the proteins on our site.

Function Related Protein
I-SMAD bindingSMAD6;AXIN1;TGFBR1;AXIN2;SMAD7;SMAD4;TGFB1I1;SMAD1;CTNNB1
Roundabout bindingSLIT1;SLIT1B;SLIT2;UBE4A;GM4980;SLIT1A;SLIT3;TGFB1I1
androgen receptor bindingNRIP1;PRKCB;NCOA1;TGFB1I1;PRMT2;PARK7;BRCA1;Ar;CDK7
protein bindingMAGEA2;CBX4;MTX2;PSG5;LCOR;TPCN2;EIF4B;TPSB2;JRK
transcription coactivator activityMTDH;IL31RA;BRD7;PIAS1;RXRB;YY1;TFDP1B;MED21;ATF6
zinc ion bindingABLIM2;ZDHHC7;LTN1;TRIM28;CBLB;FTR43;VDR;RNF34;GFI1

TGFB1I1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TGFB1I1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TGFB1I1.

PTK2; ITGA4; VHL; CCNA1; CDKN2B; ilvD; kdpE; kbl; HIPK3; UBQLN4; PLA2G3; q9wmx2-pro_0000037548; SH2D1B; PLEKHH2

Derer, S; Till, A; et al. mTNF reverse signalling induced by TNF alpha antagonists involves a GDF-1 dependent pathway: implications for Crohn's disease. GUT 62:376-386(2013).
Lai, CF; Chen, YM; et al. Cysteine-Rich Protein 61 Plays a Proinflammatory Role in Obstructive Kidney Fibrosis. PLOS ONE 8:-(2013).
TGF
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