tk1
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  • Official Full Name
  • thymidine kinase 1, soluble
  • Background
  • Thymidine kinase 1, soluble (gene name TK1), is a human thymidine kinase.
  • Synonyms
  • TK1; thymidine kinase 1, soluble; thymidine kinase, cytosolic; thymidine kinase-1; thymidine kinase 1 soluble isoform; TK2
Cat.#:TK1-31518THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TK1, His-tagged
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Cat.#:TK1-3247HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TK1, His-tagged
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Cat.#:TK1-8093HTag:His|GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TK1 protein, His & GST-tagged
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Cat.#:TK1-913HTag:DDK
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human TK1 Protein, DDK-tagged
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Cat.#:TK1-6460CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken TK1
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Cat.#:TK1-10208ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish TK1
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Cat.#:TK1-1342HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Thymidine Kinase 1, Soluble, His-tagged
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Cat.#:TK1-1783HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human TK1 cell lysate
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Involved Pathway

TK1 involved in several pathways and played different roles in them. We selected most pathways TK1 participated on our site, such as Pyrimidine metabolism, Drug metabolism - other enzymes, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with TK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Pyrimidine metabolism
POLR1E; NT5C1B-RDH14; POLR3E; UPRT; POLR1B; ENTPD4; UCK2B; POLE2; TYMS; POLR3K
Drug metabolism - other enzymes
UGT2A1; CYP2A6; NAT2; UGT1A6B; UCK2B; UPB1; PNAT10; UCK2; DPYS; CDA
Metabolic pathways
ACSL4B; ALG1; HMGCLL1; DPYD; FECH; PDXKB; FBP1A; ACSL1; GALNT14; UGDH

Protein Function

TK1 has several biochemical functions, for example, ATP binding, identical protein binding, nucleoside kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TK1 itself. We selected most functions TK1 had, and list some proteins which have the same functions with TK1. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein SLFN5; PNCK; ATP2B1A; MYO1H; KIF4A; PPP1CA; PIP5K1B; EK1; AK7A; TRNT1
Function identical protein binding
Related Protein ADIPOR1; THBS1; TRIM55; SP100; DNM1L; SLC22A1; HOOK3; TNF; RAD52; SMAD3
Function nucleoside kinase activity
Related Protein DGUOK; UCK1; TK1; UCK2A; DCK; UCK2; UCK2B
Function protein binding
Related Protein DIAP1; TEK; PITPNC1; SHROOM2; PELI2; RAMP1; FAM113A; SLC7A11; SDC4; TREML1
Function thymidine kinase activity
Related Protein TK1; TK2
Function zinc ion binding
Related Protein HERC2; NPSN; BMP1A; Ar; USP49; SETDB1; MDM4; RLIM; TRIM35-27; TLL2

Interacting Protein

TK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of TK1.
MAGEA4; GDF9; GAPDH; TP53; APLP1; TLE1; UNC119; TUBB2A; CRMP1