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TRAIP

Official Full Name

TRAF interacting protein
Overview

This gene encodes a protein that contains an N-terminal RING finger motif and a putative coiled-coil domain. A similar murine protein interacts with TNFR-associated factor 1 (TRAF1), TNFR-associated factor 2 (TRAF2), and cylindromatosis. The interaction with TRAF2 inhibits TRAF2-mediated nuclear factor kappa-B, subunit 1 activation that is required for cell activation and protection against apoptosis.
Synonyms

TRAIP; TRAF interacting protein; TRAF-interacting protein; ring finger protein 206; RNF206; TRIP;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Zebrafish

Source

E.coli
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	TRAIP-31614TH	Recombinant Human TRAIP	E.coli	N/A		Inquiry
Human	TRAIP-814HCL	Recombinant Human TRAIP 293 Cell Lysate	HEK293	N/A		Inquiry
Human	TRAIP-4815H	Recombinant Human TRAIP protein, His-tagged	E.coli	His	1-469aa	Inquiry
Human	TRAIP-4814H	Recombinant Human TRAIP protein, His-tagged	E.coli	His	1-469aa	Inquiry
Mouse	TRAIP-17294M	Recombinant Mouse TRAIP Protein	Mammalian Cell	His		Inquiry
Mouse	TRAIP-9562M	Recombinant Mouse TRAIP Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	TRAIP-9562M-B	Recombinant Mouse TRAIP Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	TRAIP-11644Z	Recombinant Zebrafish TRAIP	Mammalian Cell	His		Inquiry
Chicken	TRAIP-2299C	Recombinant Chicken TRAIP	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
TRAIP Related Articles

TRAIP involved in several pathways and played different roles in them. We selected most pathways TRAIP participated on our site, such as TNF-alpha/NF-kB Signaling Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRAIP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
TNF-alpha/NF-kB Signaling Pathway	NR2C2;DCAF7;PEG3;CAPN3;TNIP1;PDCD2;PAPOLA;KIAA1967;COMMD1

TRAIP has several biochemical functions, for example, ligase activity, protein binding, receptor signaling protein activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRAIP itself. We selected most functions TRAIP had, and list some proteins which have the same functions with TRAIP. You can find most of the proteins on our site.

Function	Related Protein
ligase activity	PRPF19;TRIM4;UBE3C;RNF123;PIAS2;CBLB;DZIP3;MGRN1;MARCH5
protein binding	DEPDC1;CBFB;ILF3;OFCC1;BCKDHA;SCARF1;ACCS;PIM1;MYO6
receptor signaling protein activity	PLCG1;KLK1B3;IFITM1;RGS12;RGS14;PDCL;FLRT3;FLRT1;TYROBP
ubiquitin protein ligase activity	PJA1;RNF24;UBE2T;TRIM32;DZIP3;MED27;RNF19A;RNF146;RNF139
zinc ion binding	RNF11;MMP10;HNF4G;PPARD;ZSWIM4;CXXC4;ZNRF2;SIRT3;TRIM61

TRAIP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRAIP here. Most of them are supplied by our site. Hope this information will be useful for your research of TRAIP.

MAPRE2; FYN; NCK1; PLCG1; GRB2; HIP2; UBOX5; TRIM23; UBE2H; RNF4; UBE2U; TRIM41; TSG101; UBE2Z; RNF114

Hostager, BS; Kashiwada, M; et al. HOIL-1L Interacting Protein (HOIP) Is Essential for CD40 Signaling. PLOS ONE 6:-(2011).

Hostager, BS; Fox, DK; et al. HOIL-1L Interacting Protein (HOIP) as an NF-kappa B Regulating Component of the CD40 Signaling Complex. PLOS ONE 5:-(2010).