trim41
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  • Official Full Name
  • tripartite motif containing 41
  • Background
  • This gene encodes a member of the tripartite motif (TRIM) family. The TRIM family is characterized by a signature motif composed of a RING finger, one or more B-box domains, and a coiled-coil region. This encoded protein may play a role in protein kinase C signaling. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • TRIM41; tripartite motif containing 41; E3 ubiquitin-protein ligase TRIM41; MGC1127; RINCK; RING finger protein that interacts with C kinase; RING finger-interacting protein with C kinase; RING-finger protein that interacts with C kinase; MGC31991
Cat.#:TRIM41-447HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human TRIM41 Protein, His-tagged
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Cat.#:TRIM41-17370MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse TRIM41 Protein
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Cat.#:TRIM41-2376CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken TRIM41
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Involved Pathway

TRIM41 involved in several pathways and played different roles in them. We selected most pathways TRIM41 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM41 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adaptive Immune System
TRIM63; KIF3A; FBXO3; CTSD; AKT3; STUB1; ASB14; IFI30; DYNC1H1; NRG4
Antigen processing: Ubiquitination &
LRSAM1; UBE2V1; DTX3L; RNF19B; MKRN1; LRR1; RNF4; LRRC41; RNF14; ASB18
Proteasome degradation
TRAF7; LTN1; UFL1; UBE2J2; UBE2L6; TRIM39; SPSB1; RNF34; RBCK1; KLHL20
Class I MHC mediated antigen processing &
UBE2J2; B2ML; ARIH2; UFL1; SPSB1; WSB1; CD207; SPSB2; GAN; LRRC41
presentation
UBR2; FCGR1B; UBE2V2; MKRN1; HECTD3; VPRBP; RNF19B; ASB11; SEC24A; UBR1
Immune System
NLRP4; TLR10; CTSH; CLEC4D; FBXO17; KLRG1; DEFB4A; DEFA1; GZMM; PELI3

Protein Function

TRIM41 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity, coenzyme F420-0 gamma-glutamyl ligase activity, coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM41 itself. We selected most functions TRIM41 had, and list some proteins which have the same functions with TRIM41. You can find most of the proteins on our site.
Function
Related Protein
Function UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
Related Protein MUL1A; MYLIPA; HECW2; HERC2; MGRN1A; NEURL1B; ITCHA; SIAH2L; ZNRF3; UBR1
Function coenzyme F420-0 gamma-glutamyl ligase activity
Related Protein MARCH4; UBR1; MYLIPA; TRIM71; ZNRF2B; MARCH9; SIAH2L; MYLIPB; RNF149; RFWD2
Function coenzyme F420-2 alpha-glutamyl ligase activity
Related Protein SIAH2L; SHRPRBCK1R; TMEM129; HECW2; ZNRF2B; RNF180; RAG1; RC3H2; ZNRF3; MARCH4
Function ligase activity
Related Protein UCHL1; RNF220; RNF111; CBX4; TTLL4; TRAIP; TRIM22; ATG3; TRIM71; MUL1A
Function metal ion binding
Related Protein CADPS; ZNF193; UBE3A; ZBTB39; ZFP629; ZFP692; PCXA; ZNF254; ITGA9; PPM1DA
Function protein binding
Related Protein SR140; SNAP23; PNMA5; DNPEP; HSCB; UNC13B; DNA2; CTH; HMMR; NBL1
Function protein-glutamic acid ligase activity
Related Protein RNF169; UBE2IA; MUL1A; HECW2; MGRN1A; MARCH11; TRIM50; MYLIPB; DTX1; RNF187
Function protein-glycine ligase activity
Related Protein RAG1; MARCH9; MYLIPA; SIAH2L; DTX1; SIAH1A; UBE2IB; MARCH11; ZNRF2B; RFWD2
Function protein-glycine ligase activity, elongating
Related Protein ITCHA; RNF149; MARCH9; UBR1; MYLIPA; MARCH5L; DTX1; HECW2; ZNRF3; RNF187
Function protein-glycine ligase activity, initiating
Related Protein MARCH4; TRIM50; TMEM129; RC3H2; RNF144AB; TRIM41; MYLIPA; RNF169; HERC2; RAG1
Function ribosomal S6-glutamic acid ligase activity
Related Protein TRIM71; UBE2M; NEURL1B; MARCH6; MARCH11; UBE2IB; RFWD2; LTN1; SHRPRBCK1R; RNF149
Function tubulin-glutamic acid ligase activity
Related Protein ARIH1L; ZNRF3; MARCH6; RNF144AA; SIAH2L; UBE2IB; MARCH4; MARCH5L; RAG1; NEURL3
Function tubulin-glycine ligase activity
Related Protein MARCH4; SIAH1A; RNF144AB; HERC2; MGRN1A; MARCH11; UBE2IB; RNF149; TRIM50; FLR
Function zinc ion binding
Related Protein USP22; ZDHHC17; MMP7; TRIM32; ZNF92; ESRRA; ESRRB; RNF220A; CSRP1A; PHF3

Interacting Protein

TRIM41 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM41 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM41.
Rpgrip1l

TRIM41 Related Articles

Cui, J; Chen, YJ; et al. Mechanisms and pathways of innate immune activation and regulation in health and cancer. HUMAN VACCINES & IMMUNOTHERAPEUTICS 10:3270-3285(2014).
Hering, DM; Olenski, K; et al. Genome-wide association study for poor sperm motility in Holstein-Friesian bulls. ANIMAL REPRODUCTION SCIENCE 146:89-97(2014).