TRIM50

  • Official Full Name

    tripartite motif containing 50

  • Synonyms

    TRIM50;tripartite motif containing 50;TRIM50A, tripartite motif containing 50 , tripartite motif containing 50A;E3 ubiquitin-protein ligase TRIM50;FLJ32804;E3 ubiquitin ligase;tripartite motif protein 50;tripartite motif-containing 50;tripartite

Recombinant Proteins

  • Mouse
  • Rat
  • Human
  • Mammalian Cells
  • HEK293
  • E. coli
  • His
  • DDK
  • Myc
  • Avi
  • Fc
  • GST

    Involved Pathway

    TRIM50 involved in several pathways and played different roles in them. We selected most pathways TRIM50 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    presentation LRSAM1,UBA5,B2ML,TRIM11,SEC24A,MKRN1,SPSB4,CYBA,RNF19B,UFL1
    Antigen processing: Ubiquitination &amp VPRBP,UFL1,RNF182,DZIP3,BLMH,LRSAM1,UBE2U,RNF220,ASB10,ATG7
    Class I MHC mediated antigen processing &amp CD207,UBE2E3,UBE2J2,CTSL2,UBE2U,ASB10,HECTD3,RNF4,ATG7,RNF41
    Adaptive Immune System KIF4A,DCTN6,CLEC2D,UBA5,KIF2C,FBXO3,CD200R3,CD207,ASB6,CLEC2G
    Immune System OSCAR,USP18,FBXO27,CLEC2G,KIF2B,IRF6,CLEC4A,UNC93B1,BST2,CD300LG
    Proteasome degradation FBXO3,ASB2,SPSB1,UBE2V2,ARIH2,TRIM11,RNF25,LRR1,SH3RF1,UFL1

    Protein Function

    TRIM50 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM50 itself. We selected most functions TRIM50 had, and list some proteins which have the same functions with TRIM50. You can find most of the proteins on our site.

    Function Related Protein
    UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity ZNRF3,RNF169,RAG1,DTX1,TRIM41,HECW2,MUL1A,MGRN1A,TMEM129,UBE2IA
    protein-glycine ligase activity, elongating ITCHA,TRIM71,MARCH5L,SIAH1A,ZNRF3,NEURL3,LTN1,RNF144AB,RFWD2,SHRPRBCK1R
    tubulin-glutamic acid ligase activity ITCHA,RFWD2,TMEM129,MUL1A,HECW2,UBR1,MARCH11,TTLL1,MARCH6,ARIH1L
    ligase activity BIRC3,NEDD4L,PIAS3,UBR7,HERC2,MGRN1,MKRN1,RNF5,RAD18,MARCH8
    coenzyme F420-2 alpha-glutamyl ligase activity SIAH2L,UBR1,MARCH6,MYLIPA,RFWD2,RNF144AB,NEURL1B,TMEM129,MARCH4,UBE2IA
    ribosomal S6-glutamic acid ligase activity MARCH9,UBE2M,HECW2,RAG1,RNF149,UBE2IB,UBE2IA,RFWD2,RNF144AB,ITCHA
    protein binding POU2AF1,MED28,CHN2,SEMA7A,HP1BP3,PRLHR,VPS45,ISY1,ERLEC1,MYLK2
    coenzyme F420-0 gamma-glutamyl ligase activity MGRN1A,MUL1A,ZNRF2B,MYLIPB,UBE2IB,TRIM71,HECW2,RNF180,RFWD2,LTN1
    protein-glycine ligase activity, initiating TTLL3,G2E3,TRIM41,HERC2,NEURL1B,DTX1,RNF144AA,RNF144AB,RC3H2,RNF169

    Interacting Protein

    TRIM50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM50 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM50.

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