TRIM50

  • Official Full Name

    tripartite motif containing 50

  • Synonyms

    TRIM50;tripartite motif containing 50;TRIM50A, tripartite motif containing 50 , tripartite motif containing 50A;E3 ubiquitin-protein ligase TRIM50;FLJ32804;E3 ubiquitin ligase;tripartite motif protein 50;tripartite motif-containing 50;tripartite

Recombinant Proteins

  • Mouse
  • Rat
  • Human
  • Mammalian Cells
  • HEK293
  • E. coli
  • His
  • DDK
  • Myc
  • Avi
  • Fc
  • GST

    Involved Pathway

    TRIM50 involved in several pathways and played different roles in them. We selected most pathways TRIM50 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System PJA1,LRR1,UFL1,GM11711,CD300LH,CD300C,IGHM,WWP1,ITGB1B.1,CD200R1
    Proteasome degradation DZIP3,PJA1,TRIM11,RNF34,KLHL20,ASB8,RBCK1,LRSAM1,UBE2E3,PJA2
    Class I MHC mediated antigen processing &amp ASB18,WWP1,ERAP1,ASB9,UBE2U,LRR1,LRRC41,TPP2,SH3RF1,FCGR1B
    Antigen processing: Ubiquitination &amp WWP1,RNF34,NPEPPS,RNF220,ASB11,STUB1,TRIM11,MKRN1,UBE2V2,ASB17
    presentation LTN1,FBXO27,ERAP2,UBE2V2,KLHL21,CTSL1,ASB8,RNF144B,CD207,UBR2
    Immune System SIGLEC7,KIR2DS2,LAIR1,DEFA6,CASP4,IFI6,IRF2,KIR3DS1,SPSB2,KIF2B

    Protein Function

    TRIM50 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM50 itself. We selected most functions TRIM50 had, and list some proteins which have the same functions with TRIM50. You can find most of the proteins on our site.

    Function Related Protein
    protein-glycine ligase activity, elongating MYLIPB,ITCHA,UBE2IA,MUL1A,MARCH11,UBE2IB,DTX1,HERC2,SIAH2L,ZNRF2B
    metal ion binding NMRK1,GLIS2,ZFP524,RORCB,LRP2,PDLIM5A,DGKQ,LRRK1,RNF44,KLF11
    coenzyme F420-2 alpha-glutamyl ligase activity ZNRF3,RC3H2,MARCH6,NEURL1B,MUL1A,RNF144AA,G2E3,RNF187,RAG1,MARCH9
    protein-glutamic acid ligase activity ZNRF3,HERC2,UBE2IB,MARCH4,RNF180,SHRPRBCK1R,MARCH9,MARCH6,NEURL3,MYLIPA
    protein-glycine ligase activity MUL1A,ARIH1L,UBE2IB,MARCH4,MARCH11,HERC2,NEURL1B,TTLL3,MARCH9,RNF144AA
    zinc ion binding ADAM8,RNF146,TRIM55B,PARP1,RAG2,ADAMTSL1,CCS,ADAM19,ESR2B,KDM5B
    UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity RNF144AA,UBR1,MARCH6,SHRPRBCK1R,UBE2IB,ZNRF3,RFWD2,TRIM71,MUL1A,MARCH5L
    protein-glycine ligase activity, initiating RNF169,MUL1A,ARIH1L,HERC2,MGRN1A,MYLIPA,TRIM41,MARCH11,UBE2IA,TMEM129
    tubulin-glycine ligase activity MGRN1A,RNF187,TRIM71,MARCH9,RNF144AB,MARCH4,ZNRF2B,MARCH5L,UBR1,TMEM129

    Interacting Protein

    TRIM50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM50 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM50.

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