TRIM50

  • Official Full Name

    tripartite motif containing 50

  • Synonyms

    TRIM50;tripartite motif containing 50;TRIM50A, tripartite motif containing 50 , tripartite motif containing 50A;E3 ubiquitin-protein ligase TRIM50;FLJ32804;E3 ubiquitin ligase;tripartite motif protein 50;tripartite motif-containing 50;tripartite

Recombinant Proteins

  • Mouse
  • Rat
  • Human
  • Mammalian Cells
  • HEK293
  • E. coli
  • His
  • DDK
  • Myc
  • Avi
  • Fc
  • GST

    Involved Pathway

    TRIM50 involved in several pathways and played different roles in them. We selected most pathways TRIM50 participated on our site, such as Adaptive Immune System,Antigen processing: Ubiquitination &amp,Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Proteasome degradation ATG7,ASB9,RNF6,RNF19B,BLMH,ASB13,TRIM41,UBE2J2,TRIM11,ASB17
    Immune System STUB1,IFIT8,PVRL2L,TRIM39,IFITM2,POLR3C,GM11711,CFHL4,SIGLEC5,IFIT14
    Class I MHC mediated antigen processing &amp ERAP1,FBXO17,ASB2,RNF111,HECTD3,ASB18,CTSL1,RNF25,TPP2,FBXO3
    presentation WSB1,DZIP3,SEC24A,HUWE1,ASB17,ASB11,LTN1,CD207,RNF41,ASB10
    Antigen processing: Ubiquitination &amp DZIP3,DTX3L,RNF6,RNF123,UBE2V2,SPSB1,TRIM39,RNF14,MKRN1,UBE2L6
    Adaptive Immune System CTLA4,SPSB2,ASB6,DYNC1H1,CYBA,SPSB4,FRS2,GM11711,STUB1,CD160

    Protein Function

    TRIM50 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity,coenzyme F420-0 gamma-glutamyl ligase activity,coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM50 itself. We selected most functions TRIM50 had, and list some proteins which have the same functions with TRIM50. You can find most of the proteins on our site.

    Function Related Protein
    protein-glycine ligase activity, initiating RNF144AA,MYLIPB,ZNRF3,TRIM71,TMEM129,SHRPRBCK1R,LTN1,UBE2IA,RNF187,RNF144AB
    coenzyme F420-2 alpha-glutamyl ligase activity G2E3,MUL1A,MGRN1A,UBE2IB,TRIM41,MARCH4,MARCH5L,RNF180,SIAH1A,RC3H2
    protein-glycine ligase activity, elongating SIAH2L,NEURL3,ARIH1L,ZNRF3,UBE2IA,SHRPRBCK1R,MGRN1A,RAG1,DTX1,RNF180
    tubulin-glycine ligase activity TRIM41,SHRPRBCK1R,MARCH5L,FLR,ZNRF2B,SIAH1A,RNF187,UBE2IB,UBR1,MARCH11
    tubulin-glutamic acid ligase activity MGRN1A,SIAH1A,MARCH9,MYLIPA,SIAH2L,RNF187,G2E3,RNF144AB,RC3H2,RFWD2
    ligase activity PJA1,C12orf51,PCXB,CBX4,TRIM4,HERC4,MYLIP,MARCH4,MUL1A,ARIH1L
    zinc ion binding USP16,FTR43,JHDM1D,SPRYD5,RASSF1,HRG,RNF133,CA12,XIAP,ING3
    coenzyme F420-0 gamma-glutamyl ligase activity NEURL1B,MGRN1A,MARCH5L,MYLIPA,NEURL3,G2E3,ARIH1L,RFWD2,ZNRF2B,RNF144AB
    protein binding VPS45,FSTL5,KDM1A,CHGB,G3BP1,EIF3G,DAG1,GP5,CYBB,NIPAL3

    Interacting Protein

    TRIM50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM50 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM50.

    Resources

    References

    Reviews

    Write a review

    Q&As

    Ask a question

    Ask a Question for All TRIM50 Products

    Required fields are marked with *

    My Review for All TRIM50 Products

    Required fields are marked with *