TRIM50 Protein, tripartite motif containing 50


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Official Full Name tripartite motif containing 50
Synonyms TRIM50; tripartite motif containing 50; TRIM50A, tripartite motif containing 50 , tripartite motif containing 50A; E3 ubiquitin-protein ligase TRIM50; FLJ32804; E3 ubiquitin ligase; tripartite motif protein 50; tripartite motif-containing 50; tripartite
    • Species :
    • Human
    • Mouse
    • Rat
    • Source :
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TRIM50-2652H Recombinant Human TRIM50 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse TRIM50-17379M Recombinant Mouse TRIM50 Protein Mammalian Cell His
    Rat TRIM50-6280R Recombinant Rat TRIM50 Protein Mammalian Cell His

    TRIM50 involved in several pathways and played different roles in them. We selected most pathways TRIM50 participated on our site, such as Adaptive Immune System, Antigen processing: Ubiquitination &amp, Proteasome degradation, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRIM50 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Adaptive Immune System CLTA; CSK; CTS7; KLB; NCR3LG1; DYNLL2; UBE2E3; TREML1; CTSC; CTSL1
    Antigen processing: Ubiquitination &amp RNF34; RBCK1; ASB2; LRSAM1; TRIM69; RNF220; TRIM63; TRIM39; BLMH; UBE2V2
    Proteasome degradation ASB11; UBR2; FBXO27; UBE2V1; ASB9; WSB1; RNF34; DTX3L; UBE2L6; HECTD3
    Class I MHC mediated antigen processing &amp TRIM11; CYBA; TRIM63; TRAF7; SEC23A; NPEPPS; ARIH2; ASB18; KLHL21; TRIM50
    presentation UBE2F; PJA1; ASB7; RNF111; ASB10; ARIH2; UBE2L6; TRIM9; SPSB4; UBE2V2
    Immune System FBXO3; SIGLEC9; KIFAP3; POLR3G; CLEC4A; DEFA3; KIF18A; PELI3; FAM49BA; CD300C

    TRIM50 has several biochemical functions, for example, UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity, coenzyme F420-0 gamma-glutamyl ligase activity, coenzyme F420-2 alpha-glutamyl ligase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by TRIM50 itself. We selected most functions TRIM50 had, and list some proteins which have the same functions with TRIM50. You can find most of the proteins on our site.

    Function Related Protein
    UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity SIAH2L; MYLIPB; RNF144AB; SHRPRBCK1R; MARCH4; MYLIPA; RNF180; TRIM50; RNF169; UBR1
    coenzyme F420-0 gamma-glutamyl ligase activity MARCH6; TRIM71; MGRN1A; TMEM129; NEURL1B; ZNRF3; RFWD2; RAG1; RC3H2; UBE2IA
    coenzyme F420-2 alpha-glutamyl ligase activity HERC2; NEURL1B; MARCH5L; MGRN1A; TRIM71; TRIM41; G2E3; MARCH4; RNF149; UBR1
    ligase activity RFFL; BIRC2; TNFAIP3; TRIM6; RNF212; TRIM31; LIG4; HERC2; TRIM24; UNKL
    metal ion binding PPTC7A; KAT5; ZNF410; ZNF692; HDHD2; AKAP13; CYP2P8; AMY1B; MOB3C; ZNF658
    protein binding FAM131C; INPP5D; ZC3H14; CMTM2A; POLH; MT1G; UNC13A; USP19; BMP2; POLR1B
    protein-glutamic acid ligase activity RNF144AB; ZNRF3; SHRPRBCK1R; LTN1; DTX1; TRIM71; MARCH11; UBE2IB; HERC2; SIAH1A
    protein-glycine ligase activity G2E3; MARCH4; UBR1; SIAH2L; RFWD2; ITCHA; ARIH1L; MYLIPA; RC3H2; RNF187
    protein-glycine ligase activity, elongating NEURL3; MARCH4; ZNRF3; LTN1; DTX1; MYLIPB; TRIM71; RNF187; RC3H2; ITCHA
    protein-glycine ligase activity, initiating RFWD2; UBR1; SHRPRBCK1R; RC3H2; TRIM41; TMEM129; HERC2; ZNRF2B; G2E3; TTLL3
    ribosomal S6-glutamic acid ligase activity MGRN1A; UBR1; NEURL1B; RNF169; ARIH1L; TMEM129; UBE2IA; LTN1; MARCH6; RNF187
    tubulin-glutamic acid ligase activity RNF144AB; NEURL3; MARCH6; G2E3; RNF149; SIAH2L; RNF187; MYLIPA; SHRPRBCK1R; RNF180
    tubulin-glycine ligase activity MYLIPB; UBE2IA; NEURL1B; RNF144AA; G2E3; HERC2; RNF180; SIAH2L; MARCH4; MARCH5L
    zinc ion binding PAPLNB; ZNF638; GATA6; DPEP1; TRIM42; RAI1; ZDHHC16A; ZCCHC4; ANPEP; ZEB1

    TRIM50 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRIM50 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRIM50.

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