TRPV4 Protein, transient receptor potential cation channel, subfamily V, member 4


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Official Full Name transient receptor potential cation channel, subfamily V, member 4
Background a cation-selective channel; activated in response to systemic osmotic pressure
Synonyms TRPV4; transient receptor potential cation channel, subfamily V, member 4; transient receptor potential cation channel subfamily V member 4; CMT2C; osmosensitive transient receptor potential channel 4; OTRPC4; TRP12; VR OAC; VRL 2; VROAC; osm-9-like TRP c
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Zebrafish
    • Source :
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TRPV4-730HCL Recombinant Human TRPV4 293 Cell Lysate HEK293 N/A
    Human TRPV4-731HCL Recombinant Human TRPV4 293 Cell Lysate HEK293 N/A
    Mouse TRPV4-17463M Recombinant Mouse TRPV4 Protein Mammalian Cell His
    Rat TRPV4-6305R Recombinant Rat TRPV4 Protein Mammalian Cell His
    Chicken TRPV4-6258C Recombinant Chicken TRPV4 Mammalian Cell His
    Zebrafish TRPV4-3831Z Recombinant Zebrafish TRPV4 Mammalian Cell His

    TRPV4 involved in several pathways and played different roles in them. We selected most pathways TRPV4 participated on our site, such as Inflammatory mediator regulation of TRP channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRPV4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Inflammatory mediator regulation of TRP channels PLCG1; PIK3CD; CYP4A14; CYP2C38; NGF; ALOX12; CAMK2A; PIK3R5; PRKCH; ITPR3

    TRPV4 has several biochemical functions, for example, ATP binding, SH2 domain binding, actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRPV4 itself. We selected most functions TRPV4 had, and list some proteins which have the same functions with TRPV4. You can find most of the proteins on our site.

    Function Related Protein
    SH2 domain binding SIT1; NLK; NUP62; LILRB1; PTK2; INPPL1; SYP; MS4A2; LAX1; IRS1
    actin binding PARVA; MYHC4; WASLB; CNN1; MKL1; MYH10; XIRP1; PHACTR3A; HDAC6; CNN3
    actin filament binding SSFA2; VCLA; FSCN2A; MYH10; MTSS1; TAGLN3A; HIST1H2AH; MYH11; ACTN2B; BLOC1S6
    alpha-tubulin binding PACRG; C9orf24; RACGAP1; WASH; BBS4; ARL8A; WASH1; OFD1; DDL-2; B4GALT1
    beta-tubulin binding OST4; CASC1; IFT74; SPAST; TBCD; RGS2; GABARAPL1; PIFO; PDCD5; VAPB
    calcium channel activity CACNG7A; TRPC4A; SLC24A4; CACFD1; AKR1C1; TRPM8; TRPM6; PSEN1; GRIN2B; ITPR3
    calmodulin binding CAMK2B1; ADD3; EDF1; MKNK2A; PPP3R1; RGS2; PCP4; INVS; RASGRF2; RYR1
    cation channel activity GRIN2A; GRIN3B; ASIC4B; ASIC4A; TRPC1; FAM26E; PKD1; FAM26F; MCOLN1; CALHM2
    microtubule binding REEP1; FTCD; REEP4; GAS2L3; PRNP; TUBGCP5; KIF17; KIF1B; MTAP7D3; HDAC6
    osmosensor activity TRPV4
    protein binding Shh; LMNA; FYN; SUMO3; LILRB3; NUP205; RCN1; PELP1; TTC37; CASQ2
    protein kinase C binding FLNA; DACT3; HDAC5; DSP; UGT1A7; HDAC9; AKT1; AVPR1B; LDB3; PKN1
    protein kinase binding TRP53; PPP1R12C; TTN; NR4A3; SCN5A; PRKAG3; AKAP1; CACNB3; RFFL; TCTN2
    stretch-activated, cation-selective, calcium channel activity TRPV4

    TRPV4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRPV4 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRPV4.

    HIF1AN; RAN; ouabain; ARRB2; CANX

    Dussor, G; Yan, J; et al. Targeting TRP Channels For Novel Migraine Therapeutics. ACS CHEMICAL NEUROSCIENCE 5:1085-1096(2014).
    Lee, JC; Choe, SY; et al. Age-related changes in the distribution of transient receptor potential vanilloid 4 channel (TRPV4) in the central nervous system of rats. JOURNAL OF MOLECULAR HISTOLOGY 45:497-505(2014).

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