|Official Full Name||transient receptor potential cation channel, subfamily V, member 4|
|Background||a cation-selective channel; activated in response to systemic osmotic pressure|
|Synonyms||TRPV4; transient receptor potential cation channel, subfamily V, member 4; transient receptor potential cation channel subfamily V member 4; CMT2C; osmosensitive transient receptor potential channel 4; OTRPC4; TRP12; VR OAC; VRL 2; VROAC; osm-9-like TRP c|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
TRPV4 involved in several pathways and played different roles in them. We selected most pathways TRPV4 participated on our site, such as Inflammatory mediator regulation of TRP channels, which may be useful for your reference. Also, other proteins which involved in the same pathway with TRPV4 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Inflammatory mediator regulation of TRP channels||PLCG1; PIK3CD; CYP4A14; CYP2C38; NGF; ALOX12; CAMK2A; PIK3R5; PRKCH; ITPR3|
TRPV4 has several biochemical functions, for example, ATP binding, SH2 domain binding, actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TRPV4 itself. We selected most functions TRPV4 had, and list some proteins which have the same functions with TRPV4. You can find most of the proteins on our site.
|ATP binding||CMPK2; HLCS; P2RX4B; TBCK; PAPSS2A; STK17B; MAP2K4; PIM2; MAPK7; MAP3K4|
|SH2 domain binding||SIT1; NLK; NUP62; LILRB1; PTK2; INPPL1; SYP; MS4A2; LAX1; IRS1|
|actin binding||PARVA; MYHC4; WASLB; CNN1; MKL1; MYH10; XIRP1; PHACTR3A; HDAC6; CNN3|
|actin filament binding||SSFA2; VCLA; FSCN2A; MYH10; MTSS1; TAGLN3A; HIST1H2AH; MYH11; ACTN2B; BLOC1S6|
|alpha-tubulin binding||PACRG; C9orf24; RACGAP1; WASH; BBS4; ARL8A; WASH1; OFD1; DDL-2; B4GALT1|
|beta-tubulin binding||OST4; CASC1; IFT74; SPAST; TBCD; RGS2; GABARAPL1; PIFO; PDCD5; VAPB|
|calcium channel activity||CACNG7A; TRPC4A; SLC24A4; CACFD1; AKR1C1; TRPM8; TRPM6; PSEN1; GRIN2B; ITPR3|
|calmodulin binding||CAMK2B1; ADD3; EDF1; MKNK2A; PPP3R1; RGS2; PCP4; INVS; RASGRF2; RYR1|
|cation channel activity||GRIN2A; GRIN3B; ASIC4B; ASIC4A; TRPC1; FAM26E; PKD1; FAM26F; MCOLN1; CALHM2|
|microtubule binding||REEP1; FTCD; REEP4; GAS2L3; PRNP; TUBGCP5; KIF17; KIF1B; MTAP7D3; HDAC6|
|protein binding||Shh; LMNA; FYN; SUMO3; LILRB3; NUP205; RCN1; PELP1; TTC37; CASQ2|
|protein kinase C binding||FLNA; DACT3; HDAC5; DSP; UGT1A7; HDAC9; AKT1; AVPR1B; LDB3; PKN1|
|protein kinase binding||TRP53; PPP1R12C; TTN; NR4A3; SCN5A; PRKAG3; AKAP1; CACNB3; RFFL; TCTN2|
|stretch-activated, cation-selective, calcium channel activity||TRPV4|
TRPV4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TRPV4 here. Most of them are supplied by our site. Hope this information will be useful for your research of TRPV4.
HIF1AN; RAN; ouabain; ARRB2; CANX