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TUBA1B

  • Official Full Name

    tubulin, alpha 1b

  • Overview

    Microtubules are required for many well characterized functions in eukaryotic cells, including the movement of chromosomes in mitosis and meiosis, intracellular transport, establishment and maintenance of cellular morphology, cell growth, cell migration and morphogenesis in multicellular organisms. The building block of a microtubule is the tubulin subunit, a heterodimer of alpha and beta-tubulin. Both of these monomers are found in all eukaryotes, and their sequences are highly conserved. Acetylated alpha tubulin is present in various microtubule structures and plays a role in stabilizing the structures of all microtubules.
  • Synonyms

    TUBA1B; tubulin, alpha 1b; K-ALPHA-1; tubulin alpha-1B chain; alpha tubulin; tubulin K-alpha-1; alpha-tubulin ubiquitous; tubulin, alpha, ubiquitous; tubulin alpha-ubiquitous chain; Acetylated alpha tubulin;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mamanlian cells
  • Mammalian Cell
  • Wheat Germ
  • C
  • His
  • Flag
  • GST
  • His (Fc)
  • Avi
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human TUBA1B-3486H Recombinant Human TUBA1B, GST-tagged E.coli GST 1-451aa
Human TUBA1B-26H Recombinant Human TUBA1B protein, MYC/DDK-tagged HEK293 Myc/DDK
Human TUBA1B-38H Recombinant Human TUBA1B, His-tagged E.coli His
Human TUBA1B-31629TH Recombinant Human TUBA1B Wheat Germ N/A 451 amino acids
Human TUBA1B-661HCL Recombinant Human TUBA1B 293 Cell Lysate HEK293 N/A
Human TUBA1B-8274HFL Recombinant Full Length Human TUBA1B protein, Flag-tagged Mamanlian cells Flag
Human TUBA1B-534HF Recombinant Full Length Human TUBA1B Protein In Vitro Cell Free System 451 amino acids
Human TUBA1B-508H Recombinant Human TUBA1B Protein, His-tagged E.coli N-His Met1-Tyr451
Human TUBA1B-5529H Recombinant Human TUBA1B Protein (Met1-Tyr451), C-His tagged E.coli C-His Met1-Tyr451
Mouse TUBA1B-17609M Recombinant Mouse TUBA1B Protein Mammalian Cell His
Mouse TUBA1B-9753M-B Recombinant Mouse TUBA1B Protein Pre-coupled Magnetic Beads HEK293
Mouse TUBA1B-9753M Recombinant Mouse TUBA1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat TUBA1B-6355R Recombinant Rat TUBA1B Protein Mammalian Cell His
Rat TUBA1B-6011R-B Recombinant Rat TUBA1B Protein Pre-coupled Magnetic Beads HEK293
Rat TUBA1B-6011R Recombinant Rat TUBA1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey TUBA1B-1061C Recombinant Cynomolgus TUBA1B Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey TUBA1B-804C-B Recombinant Cynomolgus Monkey TUBA1B Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey TUBA1B-804C Recombinant Cynomolgus Monkey TUBA1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque TUBA1B-5024R Recombinant Rhesus monkey TUBA1B Protein, His-tagged Mammalian Cell His
Rhesus Macaque TUBA1B-4837R Recombinant Rhesus Macaque TUBA1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque TUBA1B-4837R-B Recombinant Rhesus Macaque TUBA1B Protein Pre-coupled Magnetic Beads HEK293
Zebrafish TUBA1B-9738Z Recombinant Zebrafish TUBA1B Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • TUBA1B Related Articles

TUBA1B involved in several pathways and played different roles in them. We selected most pathways TUBA1B participated on our site, such as Chaperonin-mediated protein folding, Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding, Formation of tubulin folding intermediates by CCT/TriC, which may be useful for your reference. Also, other proteins which involved in the same pathway with TUBA1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chaperonin-mediated protein foldingCCT2;PFDN6;VBP1;TUBA1B;CCT5;TUBA3D;FBXW5;NOP56;PFDN2
Cooperation of Prefoldin and TriC/CCT in actin and tubulin foldingPFDN5;CCT6A;CCT5;TUBB4B;VBP1;TUBB4A;CCT4;CCT7;TCP1
Formation of tubulin folding intermediates by CCT/TriCTCP1;CCT2;CCT7;CCT5;TUBA3D;CCT6A;TUBA1B;TUBB4A;CCT3
Gap junctionAdcy4;TUBA4L;PDGFRB;GRB2;PRKACAA;PRKCBA;GNA15.1;ADRB3B;TUBA1L2
Metabolism of proteinsMPDU1B;FBXW9;DPH5;EIF4H;PROZ;GALNT13;IGFBP6B;ZNF408;UBA2
Parkin-Ubiquitin Proteasomal System pathwayRNF19A;TUBA3E;TUBB7P;STUB1;SIAH2;HSPA7;UBE2J2;HSPA14;TUBA3D
Pathogenic Escherichia coli infectionRHOA;TUBA1C;ROCK2;CD14;FYN;TUBB7P;NCK1;NCL;CDC42
PhagosomeITGB3;SEC61AL2;ATP6V0A2B;THBS4A;FCGR2B;FCGR3A;CCDC102A;TAP2;TUBB1

TUBA1B has several biochemical functions, for example, GTP binding, GTPase activity, double-stranded RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TUBA1B itself. We selected most functions TUBA1B had, and list some proteins which have the same functions with TUBA1B. You can find most of the proteins on our site.

Function Related Protein
GTP bindingMX1;RHOAD;RTKN;GSPT2;NKIRAS1;GNAV1;GFM2;RAN;LGALS6
GTPase activityGNA12A;GNA13A;MSTO1;TUBB4B;RAB18A;DNM2A;GNAIA;RAB27B;EEF2B
double-stranded RNA bindingOAS1A;DHX15;SUPV3L1;DHX36;OAS1;DROSHA;AGO3;BARHL1;TLR3
protein bindingQARS;TNIP1;SYVN1;PEX26;ASPA;BEND5;CHRDL2;SIN3A;RAB17
structural constituent of cytoskeletonTUBA2;KRT2;TUBA3D;CYLC2;LOR;SPTBN1;BFSP2;ANK1;ACTR3
structural molecule activityCSTA;ODF2;SNTB1;LCE3C;CLDNE;CLDNB;VCL;KRT95;MTAP7D2
ubiquitin protein ligase bindingPARK2;MC4R;RBX1;GSK3B;VCL;PER1;TRIM37;MYOD1;CUL5A

TUBA1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TUBA1B here. Most of them are supplied by our site. Hope this information will be useful for your research of TUBA1B.

TUBB3; AGTRAP; EBNA-LP; YWHAZ; SMAD2; TOM1L1; TMEM253; SLX1A; STARD13; bosutinib; imatinib; dasatinib; midostaurin

Groh, KJ; Schonenberger, R; et al. Analysis of protein expression in zebrafish during gonad differentiation by targeted proteomics. GENERAL AND COMPARATIVE ENDOCRINOLOGY 193:210-220(2013).
Lu, CH; Zhang, J; et al. Increased alpha-Tubulin1b Expression Indicates Poor Prognosis and Resistance to Chemotherapy in Hepatocellular Carcinoma. DIGESTIVE DISEASES AND SCIENCES 58:2713-2720(2013).
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