TUBA1B Protein, tubulin, alpha 1b


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Official Full Name tubulin, alpha 1b
Background Microtubules are required for many well characterized functions in eukaryotic cells, including the movement of chromosomes in mitosis and meiosis, intracellular transport, establishment and maintenance of cellular morphology, cell growth, cell migration and morphogenesis in multicellular organisms. The building block of a microtubule is the tubulin subunit, a heterodimer of alpha and beta-tubulin. Both of these monomers are found in all eukaryotes, and their sequences are highly conserved. Acetylated alpha tubulin is present in various microtubule structures and plays a role in stabilizing the structures of all microtubules.
Synonyms TUBA1B; tubulin, alpha 1b; K-ALPHA-1; tubulin alpha-1B chain; alpha tubulin; tubulin K-alpha-1; alpha-tubulin ubiquitous; tubulin, alpha, ubiquitous; tubulin alpha-ubiquitous chain; Acetylated alpha tubulin
    • Species :
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human TUBA1B-26H Recombinant Human TUBA1B protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human TUBA1B-31629TH Recombinant Human TUBA1B Wheat Germ N/A
    Human TUBA1B-3486H Recombinant Human TUBA1B, GST-tagged E.coli GST
    Human TUBA1B-38H Recombinant Human TUBA1B, His-tagged E.coli His
    Human TUBA1B-661HCL Recombinant Human TUBA1B 293 Cell Lysate HEK293 N/A
    Mouse TUBA1B-17609M Recombinant Mouse TUBA1B Protein Mammalian Cell His
    Rat TUBA1B-6355R Recombinant Rat TUBA1B Protein Mammalian Cell His
    Cynomolgus Monkey TUBA1B-1061C Recombinant Cynomolgus TUBA1B Protein, His-tagged Mammalian Cell His
    Rhesus Macaque TUBA1B-5024R Recombinant Rhesus monkey TUBA1B Protein, His-tagged Mammalian Cell His
    Zebrafish TUBA1B-9738Z Recombinant Zebrafish TUBA1B Mammalian Cell His

    TUBA1B involved in several pathways and played different roles in them. We selected most pathways TUBA1B participated on our site, such as Chaperonin-mediated protein folding, Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding, Formation of tubulin folding intermediates by CCT/TriC, which may be useful for your reference. Also, other proteins which involved in the same pathway with TUBA1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Chaperonin-mediated protein folding FKBP9; FBXL5; CCT3; PFDN5; TUBA3D; CCT6A; FBXW2; PFDN2; FBXW4; CCT8
    Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding VBP1; CCT6A; CCT7; TUBA3D; PFDN6; TUBA1B; TUBB4A; PFDN4; TUBB4B; PFDN5
    Formation of tubulin folding intermediates by CCT/TriC TUBB4B; TUBA3D; CCT5; TUBB4A; CCT6A; CCT4; CCT7; CCT3; CCT8; CCT2
    Gap junction GRM5; DRD1B; DRD2B; RAF1B; TUBA3B; Adcy4; RAF1A; TUBA8L4; ADRB3B; PRKG1A
    Metabolism of proteins NSMCE1; SENP5; IGFBP6B; ST6GALNAC1.2; ADAMTSL4; CGB5; MUC21; SEC61B; PPP6C; EIF2B1
    Parkin-Ubiquitin Proteasomal System pathway UBE2J2; TUBA1B; TUBB7P; RNF19A; SIAH2; HSPA14; STUB1; TUBA3E; HSPA7; TUBA3D
    Pathogenic Escherichia coli infection NCK2; CTTN; TUBAL3; TUBB1; TLR4; TUBB6; TUBA4A; ABL1; TUBA3E; FYN
    Phagosome ATP6V1G2; FCGR3A; ATP6V0E2; H2-AA; MHC2DCB; RAC1; CD209; CTSSB.1; CD36; ITGB3B

    TUBA1B has several biochemical functions, for example, GTP binding, GTPase activity, double-stranded RNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TUBA1B itself. We selected most functions TUBA1B had, and list some proteins which have the same functions with TUBA1B. You can find most of the proteins on our site.

    Function Related Protein
    GTP binding ARL14; RABL6; GNA12A; DRG2; RAB9B; EIF2B1; GNL3; GIMAP1; RHOGD; RAP1A
    GTPase activity RAB11BA; GNAV1; GNB2; REM2; GSPT1L; GNGT1; GTPBP4; RAB40B; RRAGB; GNA15.4
    double-stranded RNA binding ZFP346; OASL1; RFTN1; TLR8; SLC3A2; MBNL1; OAS1A; IFIH1; OAS3; CLTC
    protein binding RHOBTB3; SMAD4; FGD2; RRAGD; CHD8; CXCR7; NSMCE4A; STX4; RNF111; CASP10
    structural constituent of cytoskeleton NEFH; TNNT2A; TLN1; VILL; TUBA8L2; TUBA7L; TUBA4L; BICD1; TUBB5; ACTL6B
    structural molecule activity KRT72-PS; KRT19; MAP7D1B; COPG; FLG2; CLDN18; KRT4; CLDN5B; ROCK2; CLDN15B
    ubiquitin protein ligase binding RRAGA; FAF1; CCT2; PRKAR1A; GABARAPL1; ERBB2; AXIN2; HERC2; GABARAP; DNM1L

    TUBA1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TUBA1B here. Most of them are supplied by our site. Hope this information will be useful for your research of TUBA1B.

    TUBB3; AGTRAP; EBNA-LP; YWHAZ; SMAD2; TOM1L1; TMEM253; SLX1A; STARD13; bosutinib; imatinib; dasatinib; midostaurin

    Groh, KJ; Schonenberger, R; et al. Analysis of protein expression in zebrafish during gonad differentiation by targeted proteomics. GENERAL AND COMPARATIVE ENDOCRINOLOGY 193:210-220(2013).
    Lu, CH; Zhang, J; et al. Increased alpha-Tubulin1b Expression Indicates Poor Prognosis and Resistance to Chemotherapy in Hepatocellular Carcinoma. DIGESTIVE DISEASES AND SCIENCES 58:2713-2720(2013).

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