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UBE2G2

  • Official Full Name

    ubiquitin-conjugating enzyme E2G 2

  • Overview

    The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
  • Synonyms

    UBE2G2; ubiquitin-conjugating enzyme E2G 2; ubiquitin conjugating enzyme E2G 2 (homologous to yeast UBC7) , ubiquitin conjugating enzyme E2G 2 (UBC7 homolog, yeast); ubiquitin-conjugating enzyme E2 G2; UBC7; ubiquitin-protein ligase G2; ubiquitin carrier;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Strep
  • His|SUMO
  • Myc
  • DDK
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human UBE2G2-532H Active Recombinant Human UBE2G2 Protein, His-tagged E.coli His
Human UBE2G2-99H Recombinant Human UBE2G2, His-tagged E.coli His
Human UBE2G2-126H Recombinant Human UBE2G2 E.coli N/A
Human UBE2G2-7946H Recombinant Human UBE2G2, GST-tagged E.coli GST
Human UBE2G2-127H Recombinant Human UBE2G2, His6-SUMO-tagged E.coli His/SUMO
Human UBE2G2-578HCL Recombinant Human UBE2G2 293 Cell Lysate HEK293 N/A
Human UBE2G2-577HCL Recombinant Human UBE2G2 293 Cell Lysate HEK293 N/A
Human UBE2G2-0038H Recombinant Human UBE2G2 Protein (A2-L165), Tag Free Insect Cell No tag A2-L165
Human UBE2G2-0039H Recombinant Human UBE2G2 Protein (A2-L165), His/Strep tagged Insect Cell His/Strep A2-L165
Mouse UBE2G2-17717M Recombinant Mouse UBE2G2 Protein Mammalian Cell His
Mouse UBE2G2-9829M Recombinant Mouse UBE2G2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse UBE2G2-9829M-B Recombinant Mouse UBE2G2 Protein Pre-coupled Magnetic Beads HEK293
Mouse Ube2g2-6788M Recombinant Mouse Ube2g2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque UBE2G2-5060R Recombinant Rhesus monkey UBE2G2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque UBE2G2-4873R-B Recombinant Rhesus Macaque UBE2G2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque UBE2G2-4873R Recombinant Rhesus Macaque UBE2G2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish UBE2G2-2514Z Recombinant Zebrafish UBE2G2 Mammalian Cell His
Chicken UBE2G2-4823C Recombinant Chicken UBE2G2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • UBE2G2 Related Articles
  • UBE2G2 Related Research Area

UBE2G2 involved in several pathways and played different roles in them. We selected most pathways UBE2G2 participated on our site, such as Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum, Parkinsons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2G2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ubiquitin mediated proteolysisUBR5;UBE2N;UBA7;UBA6;UBE2Z;UBE2E1;SIAH1A;UBOX5;UBA2
Protein processing in endoplasmic reticulumSELS;AMFR;UBE2J1;MARCH6;DNAJB12A;DNAJB2;VCP;SAR1AB;HSPH1
Parkinsons diseaseUBE2G1;NDUFS4;GPR37;SDHA;NDUFA12;NDUFS3;NDUFV3;NDUFB10;NDUFB7

UBE2G2 has several biochemical functions, for example, ATP binding, identical protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2G2 itself. We selected most functions UBE2G2 had, and list some proteins which have the same functions with UBE2G2. You can find most of the proteins on our site.

Function Related Protein
ATP bindingABCB4;PAK3;PTK6B;ACVRL1;TRIO;GSG2;MAPKAPK2A;PKMYT1;UBA6
identical protein bindingTP63;KHDRBS1;KCTD13;CSNK2B;SEPHS1;CD74;S100A1;AGXT2L1;APAF1
protein bindingPARVG;SOX-2;PKD1;GDAP2;GABBR2;RASSF7;ACTN4;RFFL;SYNPO2L
ubiquitin conjugating enzyme activityUBE2C;UBE2D1;UBE2J2;UBE2E3;UBE2Z;UBE2E2;UBE2S;UBE2Q1;UBE2T
ubiquitin protein ligase activityPARK2;ZNRF2;RAG1;PDZD4;UBE3A;TRIM2;TRIM71;UBE2G1;MED7
ubiquitin protein ligase bindingNKD2;FZD5;UBE2J1;OTUB1;MAGEC2;USP13;ARRB2;ATXN3;SMAD7
ubiquitin-protein transferase activityRNF146;MIB2;SMURF1;FBXL14B;RBBP6;TRIM9;UBE2E3;RNF4;PDZRN3B

UBE2G2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2G2 here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2G2.

AMFR; CORO1A

Ambivero, CT; Cilenti, L; et al. Mulan E3 ubiquitin ligase interacts with multiple E2 conjugating enzymes and participates in mitophagy by recruiting GABARAP. CELLULAR SIGNALLING 26:2921-2929(2014).
Liu, WX; Shang, YL; et al. gp78 elongates of polyubiquitin chains from the distal end through the cooperation of its G2BR and CUE domains. SCIENTIFIC REPORTS 4:-(2014).
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