ube2g2
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  • Official Full Name
  • ubiquitin-conjugating enzyme E2G 2
  • Background
  • The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
  • Synonyms
  • UBE2G2; ubiquitin-conjugating enzyme E2G 2; ubiquitin conjugating enzyme E2G 2 (homologous to yeast UBC7) , ubiquitin conjugating enzyme E2G 2 (UBC7 homolog, yeast); ubiquitin-conjugating enzyme E2 G2; UBC7; ubiquitin-protein ligase G2; ubiquitin carrier
Cat.#:UBE2G2-126HTag:
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human UBE2G2
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Cat.#:UBE2G2-127HTag:His/SUMO
Source (Host):E.coliSpecies:Human
Product nameRecombinant Human UBE2G2, His6-SUMO-tagged
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Cat.#:UBE2G2-532HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human UBE2G2 Protein, His-tagged
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Cat.#:UBE2G2-7946HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human UBE2G2, GST-tagged
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Cat.#:UBE2G2-99HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human UBE2G2, His-tagged
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Cat.#:UBE2G2-17717MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse UBE2G2 Protein
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Cat.#:UBE2G2-5060RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey UBE2G2 Protein, His-tagged
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Cat.#:UBE2G2-4823CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken UBE2G2
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Cat.#:UBE2G2-2514ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish UBE2G2
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Cat.#:UBE2G2-577HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human UBE2G2 293 Cell Lysate
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Cat.#:UBE2G2-578HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human UBE2G2 293 Cell Lysate
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Involved Pathway

UBE2G2 involved in several pathways and played different roles in them. We selected most pathways UBE2G2 participated on our site, such as Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum, Parkinsons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2G2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ubiquitin mediated proteolysis
ANAPC13; ERCC8; UBE2D2; FBXO2; UBE4B; AIRE; NEDD4L; UBE2S; UBE2H; BTRC
Protein processing in endoplasmic reticulum
RAD23A; WFS1; BAX; HSP70; DNAJC5GA; DNAJB1A; BAG2; UBE2D2; UBE2D2A; GANAB
Parkinsons disease
NDUFB9; SNCAIP; NDUFB3; ATP5A1; UBB; NDUFB6; LRRK2; COX7B; SLC25A4; MT-ND4

Protein Function

UBE2G2 has several biochemical functions, for example, ATP binding, identical protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2G2 itself. We selected most functions UBE2G2 had, and list some proteins which have the same functions with UBE2G2. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein SMG1; ADRBK2; LRRK2; RIPK4; HSP70L; PTK6B; FLJ11011L; CAMK2D1; PRKCA; TP53
Function identical protein binding
Related Protein PCM1; USP2; PAFAH1B3; FADD; CLDN7; FHIT; PIP4K2C; UBE2G2; EIF2AK3; POU3F2
Function protein binding
Related Protein PROCR; FAM156A; EHD2; ATP6V1E1; CCDC135; GINS2; NCKAP1L; PIF1; MATR3; BBC3
Function ubiquitin conjugating enzyme activity
Related Protein UBE2N; UBE2S; UBE2E1; UBE2O; UBE2R2; UBE2D2; CDC34; UBE2J2; UBE2D4; UBE2T
Function ubiquitin protein ligase activity
Related Protein SIAH2L; UBE2V2; TRIM11; RNF175; TRIM24; HECW1B; PDZRN4; AMFR; HECW2; UBE2R2
Function ubiquitin protein ligase binding
Related Protein CUL5; TXNIP; GLMN; STUB1; UBE2G1B; UBE2V1; PACRG; TCEB2; TUBA1B; PER1
Function ubiquitin-protein transferase activity
Related Protein FBXO11; FBXO25; TRAF5; MUL1B; BIRC5; TRIM28; SKP1; TRIM17; SIAH1; UBE2R2

Interacting Protein

UBE2G2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2G2 here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2G2.
AMFR; CORO1A

UBE2G2 Related Articles

Ambivero, CT; Cilenti, L; et al. Mulan E3 ubiquitin ligase interacts with multiple E2 conjugating enzymes and participates in mitophagy by recruiting GABARAP. CELLULAR SIGNALLING 26:2921-2929(2014).
Liu, WX; Shang, YL; et al. gp78 elongates of polyubiquitin chains from the distal end through the cooperation of its G2BR and CUE domains. SCIENTIFIC REPORTS 4:-(2014).