|Official Full Name||ubiquitin-conjugating enzyme E2G 2|
|Background||The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein shares 100% sequence identity with the mouse counterpart. This gene is ubiquitously expressed, with high expression seen in adult muscle. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.|
|Synonyms||UBE2G2; ubiquitin-conjugating enzyme E2G 2; ubiquitin conjugating enzyme E2G 2 (homologous to yeast UBC7) , ubiquitin conjugating enzyme E2G 2 (UBC7 homolog, yeast); ubiquitin-conjugating enzyme E2 G2; UBC7; ubiquitin-protein ligase G2; ubiquitin carrier|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
UBE2G2 involved in several pathways and played different roles in them. We selected most pathways UBE2G2 participated on our site, such as Ubiquitin mediated proteolysis, Protein processing in endoplasmic reticulum, Parkinsons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2G2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Ubiquitin mediated proteolysis||NHLRC1; BRCA1; CDH1-A; DET1; KEAP1B; HUWE1; RFWD2; UBE2L3; PIAS4; UBE3B|
|Protein processing in endoplasmic reticulum||HSC70; SIL1; DNAJC5GB; AMFR; ATXN3L; SYVN1; HSPA1A; TXNDC5; HSP90AB1; UFD1L|
|Parkinsons disease||UQCRB; UBE1Y1; UBA1; ATP5E; SLC25A4; NDUFB8; UCHL1; CASP9; UBE2L3; NDUFA2|
UBE2G2 has several biochemical functions, for example, ATP binding, identical protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2G2 itself. We selected most functions UBE2G2 had, and list some proteins which have the same functions with UBE2G2. You can find most of the proteins on our site.
|ATP binding||MAPK7; PRKCB; CKMB; TNNI3K; PANK3; EPHA6; MYH1E; ROCK1; CDC7; ACACA|
|identical protein binding||CLDN15; THG1L; RB1; SMURF2; LCP1; PDCD6; ASS1; FBLN1; DCP1A; C|
|protein binding||NCAM1A; AZU1; CFL1; PYDC1; WDHD1; TRIM37; NPL; CCDC93; CD276; GP5|
|ubiquitin conjugating enzyme activity||UBE2B; UBE2A; UBE2Q2; UBE2D2; UBE2D3; UBE2Q1; UBE2D1; UBE2G2; UBE2D4; UBE2V1|
|ubiquitin protein ligase activity||PDZRN4; RNF34; MSL2B; HERC3; NEDD4; FANCL; UBE2G1B; PJA1; DZIP3; FBXO6|
|ubiquitin protein ligase binding||AURKA; MC4R; OTUB1; KCNQ3; MOAP1; UBOX5; GABARAP; UBE2N; PRKAR1A; UBE2KA|
|ubiquitin-protein transferase activity||ANKIB1; TRIM24; NLRC4; FEM1B; MARCH8; RNF13; BARD1; RNF31; HUWE1; TRAF7|
UBE2G2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2G2 here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2G2.