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UBE2O

  • Official Full Name

    ubiquitin-conjugating enzyme E2O

  • Overview

    Ubiquitin-conjugating enzyme E2 O is a protein that in humans is encoded by the UBE2O gene.
  • Synonyms

    UBE2O; ubiquitin-conjugating enzyme E2O; ubiquitin-conjugating enzyme E2 O; E2 230K; EC=6.3.2.19; FLJ12878; KIAA1734; Likely Ortholog of Mouse Ubiquitin Conjugating Enzyme; RP23 193A16.5; UBE2O_HUMAN; Ubiquitin carrier protein O; Ubiquitin conjugating enzyme E2 O; Ubiquitin conjugating enzyme E2 of 230 kDa; ubiquitin conjugating enzyme E2O; Ubiquitin protein ligase O; Ubiquitin-conjugating enzyme E2 of 230 kDa; Ubiquitin-conjugating enzyme E2-230K; Ubiquitin-protein ligase O; E2-230K;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • Insect Cell
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Strep
  • Myc
  • DDK
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human UBE2O-651H Active Recombinant Human UBE2O Protein, GST-tagged Insect Cell GST
Human UBE2O-3541H Recombinant Human UBE2O, His-tagged E.coli His 48-339aa
Human UBE2O-1871HCL Recombinant Human UBE2O cell lysate N/A
Human UBE2O-0408H Recombinant Human UBE2O Protein (A2-K1292), His/Strep tagged Insect Cell His/Strep A2-K1292
Human UBE2O-0409H Recombinant Human UBE2O Protein (A2-K1292), Tag Free Insect Cell No tag A2-K1292
Mouse UBE2O-17727M Recombinant Mouse UBE2O Protein Mammalian Cell His
Mouse UBE2O-9834M Recombinant Mouse UBE2O Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Ube2o-6795M Recombinant Mouse Ube2o Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse UBE2O-9834M-B Recombinant Mouse UBE2O Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • UBE2O Related Articles

UBE2O involved in several pathways and played different roles in them. We selected most pathways UBE2O participated on our site, such as Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2O were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ubiquitin mediated proteolysisUBA2;UBE2N;UBE2L3B;MGRN1A;UBE2D2L;UBE2F;FZR1A;UBE2H;UBE2NA

UBE2O has several biochemical functions, for example, ATP binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2O itself. We selected most functions UBE2O had, and list some proteins which have the same functions with UBE2O. You can find most of the proteins on our site.

Function Related Protein
ATP bindingATP8B3;SLC27A5;ABCD2;SPATA5L1;SEPHS1;ACVR1L;WEE2;ATP2A2A;CKMT2
poly(A) RNA bindingGOT2;FARSA;CROP;CPNE3;ANXA2;RPGR;FYTTD1;ILF3;PABPN1
protein bindingMKI67;ERP27;KIAA1217;KLRD1;C1orf35;ROR2;ILKAP;PID1;SAP18
ubiquitin conjugating enzyme activityUBE2J2;UBE2E2;UBE2R2;UBE2H;UBE2Q1;UBE2B;UBE2J1;UBE2V1;UBE2Q2
ubiquitin protein ligase activityUBE2S;PRPF19;TRIP12;NHLRC1;HECTD1;BTRC;ZSWIM2;RNF25;UBE2A
ubiquitin protein ligase bindingMFN2;MAGEC2;UBE2U;KDM4A;RNF31;PA2G4;SUMO1;GPI1;CASC3
ubiquitin-protein transferase activityUBE2E1;MYLIP;PEX2;TRIM62;RNF31;MARCH1;RNF187;TRAF4A;FBXL14

UBE2O has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2O here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2O.

APPL1; Smad6; tat; UBE2V1; Smad7; SMAD6; BAP1; Rnf111; RLIM; al554633_hum_protein; TRIM27; RPL12

Mashtalir, N; Daou, S; et al. Autodeubiquitination Protects the Tumor Suppressor BAP1 from Cytoplasmic Sequestration Mediated by the Atypical Ubiquitin Ligase UBE2O. MOLECULAR CELL 54:392-406(2014).
Yu, J; Feng, L; et al. Vitreous proteomic analysis of idiopathic epiretinal membranes. MOLECULAR BIOSYSTEMS 10:2558-2566(2014).
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