UBE2O Protein, ubiquitin-conjugating enzyme E2O


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Official Full Name ubiquitin-conjugating enzyme E2O
Background Ubiquitin-conjugating enzyme E2 O is a protein that in humans is encoded by the UBE2O gene.
Synonyms UBE2O; ubiquitin-conjugating enzyme E2O; ubiquitin-conjugating enzyme E2 O; E2 230K; EC=; FLJ12878; KIAA1734; Likely Ortholog of Mouse Ubiquitin Conjugating Enzyme; RP23 193A16.5; UBE2O_HUMAN; Ubiquitin carrier protein O; Ubiquitin conjugating enzyme E2 O; Ubiquitin conjugating enzyme E2 of 230 kDa; ubiquitin conjugating enzyme E2O; Ubiquitin protein ligase O; Ubiquitin-conjugating enzyme E2 of 230 kDa; Ubiquitin-conjugating enzyme E2-230K; Ubiquitin-protein ligase O; E2-230K
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • Insect Cell
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human UBE2O-1871HCL Recombinant Human UBE2O cell lysate N/A
    Human UBE2O-3541H Recombinant Human UBE2O, His-tagged E.coli His
    Human UBE2O-651H Recombinant Human UBE2O Protein, GST-tagged, Active Insect Cell GST
    Mouse UBE2O-17727M Recombinant Mouse UBE2O Protein Mammalian Cell His

    UBE2O involved in several pathways and played different roles in them. We selected most pathways UBE2O participated on our site, such as Ubiquitin mediated proteolysis, which may be useful for your reference. Also, other proteins which involved in the same pathway with UBE2O were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ubiquitin mediated proteolysis ANAPC1; UBE2IA; FBXW7; CUL3A; RHOBTB2A; KLHL13; CUL4A; SIAH1; FLJ11011L; UBE2D2L

    UBE2O has several biochemical functions, for example, ATP binding, poly(A) RNA binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UBE2O itself. We selected most functions UBE2O had, and list some proteins which have the same functions with UBE2O. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding DHX35; UBE2NA; HIPK3; SPS2; P2RY2; P2RX3B; NAIP6; TP53RK; MAST4; MYO10
    poly(A) RNA binding MANF; GAR1; RPL10; SR140; CDC5L; TTC6; SNRNP40; HIST1H4I; CISD2; STXBP1
    protein binding SRGAP1; GKAP1; TRAP1; RPGRIP1; SPAT-1; NCDN; SLC4A1; AHNAK; PPP2R5B; CCDC116
    ubiquitin conjugating enzyme activity UBE2R2; UBE2O; UBE2H; UBE2G2; UBE2J2; UBE2Z; UBE2A; UBE2QL1; UBE2D2; UBE2G1
    ubiquitin protein ligase activity TRIM24; MED20; PDZRN4; BTRC; UBE2N; ZNRF2; RNF152; UBR5; FBXL22; TRIM72
    ubiquitin protein ligase binding Fzd4; TRIB3; FZD5; RELA; PINK1; UBE2Z; DAXX; ARIH1; H2-AB1; C10orf46
    ubiquitin-protein transferase activity PEX12; ITCHA; STUB1; DZIP3; TRAF4A; LMO7; BRAP; MARCH1; CBLL1; TRIM69

    UBE2O has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UBE2O here. Most of them are supplied by our site. Hope this information will be useful for your research of UBE2O.

    APPL1; Smad6; tat; UBE2V1; Smad7; SMAD6; BAP1; Rnf111; RLIM; al554633_hum_protein; TRIM27; RPL12

    Mashtalir, N; Daou, S; et al. Autodeubiquitination Protects the Tumor Suppressor BAP1 from Cytoplasmic Sequestration Mediated by the Atypical Ubiquitin Ligase UBE2O. MOLECULAR CELL 54:392-406(2014).
    Yu, J; Feng, L; et al. Vitreous proteomic analysis of idiopathic epiretinal membranes. MOLECULAR BIOSYSTEMS 10:2558-2566(2014).

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