• Official Full Name
  • unc-45 homolog A (C. elegans)
  • Background
  • UNC45A plays a role in cell proliferation and myoblast fusion, binds progesterone receptor (PGR; MIM 607311) and HSP90;(HSPCA; MIM 140571), and acts as a regulator of the progesterone receptor chaperoning pathway (Price et al., 2002;(PubMed 12356907); Chadli et al., 2006 (PubMed 16478993)).
  • Synonyms
  • UNC45A; unc-45 homolog A (C. elegans); protein unc-45 homolog A; GC UNC45; SMAP 1; smooth muscle cell associated protein 1; AW538196; FLJ10043; GCUNC 45; GCUNC45; General cell UNC45; IRO039700; MGC125248; OTTMUSP00000030133; Protein unc45 homolog A; RGD1305357; SMAP1; Stromal membrane-associated protein 1; Unc-45A; Unc45 homolog A (C. elegans); smooth muscle cell associated protein-1; smooth muscle cell-associated protein 1; SMAP-1; GC-UNC45; GCUNC-45
Source (Host):HEK293Species:Human
Product nameRecombinant Human UNC45A Protein, MYC/DDK-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human UNC45A, His-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse UNC45A Protein
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat UNC45A Protein
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey UNC45A Protein, His-tagged
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish UNC45A
Source (Host):Species:Human
Product nameRecombinant Human UNC45A 293 Cell Lysate

Protein Function

UNC45A has several biochemical functions, for example, Hsp90 protein binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by UNC45A itself. We selected most functions UNC45A had, and list some proteins which have the same functions with UNC45A. You can find most of the proteins on our site.
Related Protein
Function Hsp90 protein binding
Related Protein PPID; ERN1; RPS3; NPAS2; UNC45B; ERBB2; USP19; GBP1; CSNK2A1; UNC45A
Function protein binding
Related Protein C10orf96; EPHB6; KRT83; SFMBT1; C21orf7; SH3GL2; BCL11A; TRMT12; TMEM242; ATP6V1G1

Interacting Protein

UNC45A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with UNC45A here. Most of them are supplied by our site. Hope this information will be useful for your research of UNC45A.
MEOX2; MAX; MAX; MARCH10; MID2; 7242199; PTP4A3

UNC45A Related Articles

Bernick, EP; Zhang, PJ; et al. Knockdown and overexpression of Unc-45b result in defective myofibril organization in skeletal muscles of zebrafish embryos. BMC CELL BIOLOGY 11:-(2010).
Wohlgemuth, SL; Crawford, BD; et al. The myosin co-chaperone UNC-45 is required for skeletal and cardiac muscle function in zebrafish. DEVELOPMENTAL BIOLOGY 303:483-492(2007).