wisp3
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  • Official Full Name
  • WNT1 inducible signaling pathway protein 3
  • Background
  • This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine-rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine-rich domains: insulin-like growth factor-binding domain, von Willebrand factor type C module, thrombospondin domain and C-terminal cystine knot-like domain. This gene is overexpressed in colon tumors. It may be downstream in the WNT1 signaling pathway that is relevant to malignant transformation. Mutations of this gene are associated with progressive pseudorheumatoid dysplasia, an autosomal recessive skeletal disorder, indicating that the gene is essential for normal postnatal skeletal growth and cartilage homeostasis. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms
  • WISP3; WNT1 inducible signaling pathway protein 3; WNT1-inducible-signaling pathway protein 3; CCN6; WISP-3; CCN family member 6; PPD; LIBC; PPAC; MGC125987; MGC125988; MGC125989
Cat.#:WISP3-184HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human WNT1 Inducible Signaling Pathway Protein 3
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Cat.#:WISP3-31250THTag:Fc
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human WISP3, Fc-tagged
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Cat.#:WISP3-530HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human WISP3 Protein
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Cat.#:WISP3-18557MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse WISP3 Protein
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Cat.#:WISP3-7601ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish WISP3
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Cat.#:WISP3-306HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human WISP3 293 Cell Lysate
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Protein Function

WISP3 has several biochemical functions, for example, growth factor activity, heparin binding, insulin-like growth factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WISP3 itself. We selected most functions WISP3 had, and list some proteins which have the same functions with WISP3. You can find most of the proteins on our site.
Function
Related Protein
Function growth factor activity
Related Protein FGF16; EGF; TIMP1; IL4; AMELX; FGF6A; FGF10; MDKA; MSTN; EPGN
Function heparin binding
Related Protein APOH; APOB; WISP2; SERPIND1; PDCD5; LRPAP1; WISP3; THBS1; CCL2; KAL1
Function insulin-like growth factor binding
Related Protein IGFBP5B; HTRA3A; CTGFA; IGFBP6B; HTRA1; IGFBP2B; KAZALD1; IGFBP6A; NOV; WISP1A
Function integrin binding
Related Protein CD226; ICAM2; COL5A1; THBS4; TNN; TGFBI; SFRP2; CTGF; TSPAN8; ITGA5