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WNT2

  • Official Full Name

    wingless-type MMTV integration site family member 2

  • Synonyms

    WNT2; wingless-type MMTV integration site family member 2; INT1L1; protein Wnt-2; IRP; secreted growth factor; int-1-like protein 1; Int-1-related protein;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • CHO
  • E.coli
  • HEK293
  • Insect Cell
  • Mammalian Cell
  • Yeast
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human WNT2-298HCL Recombinant Human WNT2 293 Cell Lysate HEK293 N/A
Human WNT2-1893H Recombinant Human WNT2 protein, His-tagged E.coli His Ser26~Thr360
Human WNT2-2217H Recombinant Human WNT2 Protein (26-360 aa), His-tagged Yeast His 26-360 aa
Human WNT2-2264H Recombinant Human WNT2 protein, His-tagged Insect Cell His 26-360aa
Human WNT2-08H Active Recombinant Human Wnt-2/sFRP-1 Complex Protein CHO
Mouse WNT2-18568M Recombinant Mouse WNT2 Protein Mammalian Cell His
Mouse WNT2-10194M Recombinant Mouse WNT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Wnt2-4631M Recombinant Mouse Wnt2 protein, His-tagged E.coli His 26-360aa
Mouse WNT2-10194M-B Recombinant Mouse WNT2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque WNT2-5218R Recombinant Rhesus monkey WNT2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque WNT2-5031R Recombinant Rhesus Macaque WNT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque WNT2-5031R-B Recombinant Rhesus Macaque WNT2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish WNT2-8589Z Recombinant Zebrafish WNT2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • WNT2 Related Articles
  • WNT2 Related Gene Family
  • WNT2 Related Research Area
  • WNT2 Related Signal Pathway

WNT2 involved in several pathways and played different roles in them. We selected most pathways WNT2 participated on our site, such as Wnt signaling pathway, Hedgehog signaling pathway, Hippo signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with WNT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Wnt signaling pathwayCCND1;WNT5B;CACYBP;RUVBL1;PRICKLE2B;CCND3;PPP3CC;NFATC2;FZD8
Hedgehog signaling pathwayWNT1;FBXW11B;GLI2;RAB23;WNT16;SAP18;PRKACBB;CSNK1G1;CSNK1G2B
Hippo signaling pathwayWNT7B;INADL;GSK3B;CRB2;NKD1;LLGL2;CCND3;TEAD2;RASSF1
Signaling pathways regulating pluripotency of stem cellsINHBA;INHBE;MAP2K2;SMAD9;BMPR2;HOXB1;GSK3B;BMP4;WNT7A
MelanogenesisAdcy4;GNA15.1;WNT10B;PRKACAA;CALM3B;FZD5;CAMK2A;CREB3L1;PRKACAB
HTLV-I infectionTNFRSF13C;MSX1;PDGFRB;WNT2B;IL2RB;WNT16;TNF;POLD4;CRTC1
Pathways in cancerAPPL1;ABL1;AGTR1A;RALGDS;PLEKHG5;WNT2;FADD;FGF17;FGF16
Proteoglycans in cancerPLCG1;PRKACB;NRAS;HCLS1;PIK3R1;SMO;WNT4;VTN;MMP9
Basal cell carcinomaFZD2;AXIN1;APC2;WNT6;FZD7;WNT8A;FZD8;SUFU;PTCH2

WNT2 has several biochemical functions, for example, cytokine activity, frizzled binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by WNT2 itself. We selected most functions WNT2 had, and list some proteins which have the same functions with WNT2. You can find most of the proteins on our site.

Function Related Protein
cytokine activityTNFRSF11B;TXLNA;CMTM2;SP100;IL4;CCL38.1;CLCF1;GDF6B;SCGB3A1
frizzled bindingDVL3A;FZD1;WNT5A;DVL1;WNT1;WNT2BB;WNT11;WNT2B;WNT7AA
protein bindingNPPA;FIS1;RAB7L1;MS4A12;LGR6;CD163;TSGA10;DLC1;TCEB2
receptor agonist activityWNT10B;WNT1;VEGFA;CXCL13;GREM1;WNT2;GAS6;WNT5A;WNT7A

WNT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with WNT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of WNT2.

SFRP1; UQCR11; HCK; AQP5; RRAGC

Li, QS; Yu, P; et al. GENE EXPRESSION PROFILES OF VARIOUS CYTOKINES IN MESENCHYMAL STEM CELLS DERIVED FROM UMBILICAL CORD TISSUE AND BONE MARROW FOLLOWING INFECTION WITH HUMAN CYTOMEGALOVIRUS. CELLULAR & MOLECULAR BIOLOGY LETTERS 19:140-157(2014).
Chen, J; Fu, L; et al. IDENTIFICATION OF ANTI-WNT2 MOUSE MONOCLONAL ANTIBODY AS A TARGETED ANTICANCER THERAPY IN ESOPHAGEAL SQUAMOUS CELL CARCINOMA. ANNALS OF ONCOLOGY 24:25-25(2013).
WNT
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