|Official Full Name||exportin 1|
|Background||The protein encoded by this gene mediates leucine-rich nuclear export signal (NES)-dependent protein transport. Exportin 1 specifically inhibits the nuclear export of Rev and U snRNAs. It is involved in the control of several cellular processes by controlling the localization of cyclin B, MPAK, and MAPKAP kinase 2. This protein also regulates NFAT and AP-1. [provided by RefSeq, Jul 2008]|
|Synonyms||XPO1; exportin 1; emb; CRM1; exp1; exportin-1; CRM1, yeast, homolog; exportin 1 (CRM1 homolog, yeast); chromosome region maintenance 1 homolog; chromosome region maintenance 1 protein homolog; exportin-1 (required for chromosome region maintenance);|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
XPO1 involved in several pathways and played different roles in them. We selected most pathways XPO1 participated on our site, such as Ribosome biogenesis in eukaryotes, RNA transport, Influenza A, which may be useful for your reference. Also, other proteins which involved in the same pathway with XPO1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Ribosome biogenesis in eukaryotes||IMP3; CSNK2A2A; WDR36; ACK2; REXO2; UTP14C; UTP15; XRN1; GNL3L; CIRH1A|
|RNA transport||TPRB; EIF1B; CYFIP2; RAE1; NXF3; ALYREF; PAIP1; TGS1; SNUPN; POM121L2|
|Influenza A||PIK3R2; CASP1; MAP2K7; PRKCB; DDX39B; KPNA2; AKT2; IFNA12; PIK3R5; TLR7|
|HTLV-I infection||CD3E; SFPI1; PDGFB; H2-AB1; TCF3; PRKACA; WNT1; SLC25A31; DVL2; VDAC3|
|Epstein-Barr virus infection||POLR2C; MAPK9; CD44; AKAP8L; TP53; YWHAH; CDK1; TAB2; AKT2; CD40|
XPO1 has several biochemical functions, for example, RNA binding, Ran GTPase binding, nucleocytoplasmic transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by XPO1 itself. We selected most functions XPO1 had, and list some proteins which have the same functions with XPO1. You can find most of the proteins on our site.
|RNA binding||SURF6; NANOS3; EIF4EA; NCBP1; IFIT14; DIS3; BXDC2; RBM4B; SUPV3L1; RPS3|
|Ran GTPase binding||RANBP2; NUTF2; TNPO1; NUP153; TNPO2; XPO6; BIRC5; IPO13; XPO1; IPO11|
|nucleocytoplasmic transporter activity||NUP153; NUP214; XPO1; NUP35; NUP133; TPR; NUP160; UPF3A; NUP107; NUPL1|
|protein binding||YWHAE; GMCL1; C2orf51; CAP2; PAX9; CNST; FAH; CCT4; WDR61; TEF|
|protein domain specific binding||SFN; FOXH1; ARFIP2A; ACSL3; RAPGEF3; CHMP2B; LIN7B; TH; E2F4; RAB27A|
|protein transporter activity||KPNA3; EIF4ENIF1; TIMM10; IPO13; IPO11; AP1S3A; AP1G1; AP1G2; AP2A1; ARFGAP3|
|transporter activity||SLC13A1; TMEM184B; SLC15A2; SLC25A31; AQP3A; AQP10B; ATP5J; CLVS2; MFSD9; LCN5|
XPO1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with XPO1 here. Most of them are supplied by our site. Hope this information will be useful for your research of XPO1.
YWHAZ; VCAM1; BIRC5; vpu; TGS1; HAX1; ERBB2; TP53; RCC1