Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

ZFYVE1

Official Full Name

zinc finger, FYVE domain containing 1
Overview

The FYVE domain mediates the recruitment of proteins involved in membrane trafficking and cell signaling to phosphatidylinositol 3-phosphate (PtdIns(3)P)-containing membranes. This gene encodes a protein which contains two zinc-binding FYVE domains in tandem. This protein displays a predominantly Golgi, endoplasmic reticulum and vesicular distribution. Alternatively spliced transcript variants have been found for this gene, and they encode two isoforms with different sizes.
Synonyms

ZFYVE1; zinc finger, FYVE domain containing 1; zinc finger protein, subfamily 2A (FYVE domain containing), 1 , ZNFN2A1; zinc finger FYVE domain-containing protein 1; DFCP1; KIAA1589; TAFF1; Double FYVE containing protein 1; Phosphoinositide binding protein SR3; SR3; Tandem FYVE fingers 1; ZFYVE 1; Zinc finger FYVE domain containing protein 1; Zinc finger protein subfamily 2A (FYVE domain containing) 1; Zinc finger protein subfamily 2A member 1; ZNFN2A1; tandem FYVE fingers-1 protein; double FYVE-containing protein 1; phosphoinositide-binding protein SR3; zinc finger protein, subfamily 2A, member 1; zinc finger protein, subfamily 2A (FYVE domain containing), 1;

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	ZFYVE1-176HCL	Recombinant Human ZFYVE1 293 Cell Lysate	HEK293	N/A	Inquiry
Mouse	ZFYVE1-10368M	Recombinant Mouse ZFYVE1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	ZFYVE1-10368M-B	Recombinant Mouse ZFYVE1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Chicken	ZFYVE1-4457C	Recombinant Chicken ZFYVE1	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein

ZFYVE1 involved in several pathways and played different roles in them. We selected most pathways ZFYVE1 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ZFYVE1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

ZFYVE1 has several biochemical functions, for example, 1-phosphatidylinositol binding, phosphatidylinositol-3,4,5-trisphosphate binding, phosphatidylinositol-3,4-bisphosphate binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZFYVE1 itself. We selected most functions ZFYVE1 had, and list some proteins which have the same functions with ZFYVE1. You can find most of the proteins on our site.

Function	Related Protein
1-phosphatidylinositol binding	PLEKHA4;PLEKHA2;SNX9;WDFY3;PICALM;PLEKHA3;CCDC167;SNX10;EEA1
phosphatidylinositol-3,4,5-trisphosphate binding	RAG2;ARHGAP9;DAPP1;RS1;PHLDA3;PIRT;ASAP1;FERMT2;ADAP2
phosphatidylinositol-3,4-bisphosphate binding	MAPKAP1;FAM21C;ANXA8;D6WSU116E;RAG2;TTPA;NCF1;PLEKHA1;ARAP3
protein binding	RAB39A;NSMCE2;LTBP1;EFCAB11;NRBF2;SCEL;CHMP1A;IL15;TRP53
zinc ion binding	MYT1;TP53I3;ZFAND4;ZFYVE19;MUL1;RNF152;S100A5;CRIP3;PCGF3

ZFYVE1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZFYVE1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZFYVE1.

pi3p; PPP1CA; BCL2L1; TBC1D5