• Official Full Name
  • zinc fingers and homeoboxes 1
  • Background
  • The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 1 of this gene family. In addition to forming homodimers, this protein heterodimerizes with members 2 and 3 of the zinc fingers and homeoboxes family. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 8 open reading frame 76 (C8orf76) gene.
  • Synonyms
  • ZHX1; zinc fingers and homeoboxes 1; zinc fingers and homeoboxes protein 1; ZHX 1; ZHX-1; ZHX1_HUMAN; Zinc finger and homeodomain protein 1; Zinc fingers and homeobox 1; OTTHUMP00000228386; OTTHUMP00000228389
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ZHX1, GST-tagged
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ZHX1 Protein
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ZHX1 Protein
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ZHX1 Protein, His-tagged
Source (Host):Species:Human
Product nameRecombinant Human ZHX1 cell lysate

Protein Function

ZHX1 has several biochemical functions, for example, DNA binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZHX1 itself. We selected most functions ZHX1 had, and list some proteins which have the same functions with ZHX1. You can find most of the proteins on our site.
Related Protein
Function DNA binding
Related Protein MEIS4.1A; ZFP518A; SIX1; FOXO4; FOXQ1B; ADAR; CASP8AP2; CDX1A; HIST1H2A9; STAT1A
Function metal ion binding
Related Protein HIVEP3; GLRX3; PVALB1; NLN; ZBTB8B; GLI3; HIC2; EXO1; NT5M; ZNF582
Function protein binding
Related Protein IL24; CCDC92; ELL; RABL2; COMMD6; MAGED1; GEM; ISCA2; UGGT2; SLC8A1
Function protein heterodimerization activity
Related Protein MYH7; OSTB; VOX; ABCG1; IL12A; Bcl2a1b; VEGFA; NAE1; GM5506; RALGAPA1
Function transcription corepressor activity
Related Protein TGIF1; DDX54; NEUROD2; BCL11A; TFCP2L1; BASP1; PFDN5; NRIP1; ELK3; ENO1
Function transcription factor activity, sequence-specific DNA binding
Related Protein PAX3; NFIL3-2; FOXA3; HOXB6B; NFYB; E2F1; ZNF821; NPAS2; ZNF157; NR4A2A

Interacting Protein

ZHX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZHX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZHX1.