zhx1
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  • Official Full Name
  • zinc fingers and homeoboxes 1
  • Background
  • The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 1 of this gene family. In addition to forming homodimers, this protein heterodimerizes with members 2 and 3 of the zinc fingers and homeoboxes family. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream chromosome 8 open reading frame 76 (C8orf76) gene.
  • Synonyms
  • ZHX1; zinc fingers and homeoboxes 1; zinc fingers and homeoboxes protein 1; ZHX 1; ZHX-1; ZHX1_HUMAN; Zinc finger and homeodomain protein 1; Zinc fingers and homeobox 1; OTTHUMP00000228386; OTTHUMP00000228389
Cat.#:ZHX1-3809HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ZHX1, GST-tagged
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Cat.#:ZHX1-19173MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse ZHX1 Protein
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Cat.#:ZHX1-6706RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat ZHX1 Protein
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Cat.#:ZHX1-5292RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey ZHX1 Protein, His-tagged
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Cat.#:ZHX1-1982HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ZHX1 cell lysate
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Protein Function

ZHX1 has several biochemical functions, for example, DNA binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZHX1 itself. We selected most functions ZHX1 had, and list some proteins which have the same functions with ZHX1. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein ZFP82; HNF1BA; HER6; TOX3; PARP1; ZNF23; GATA3; ERG; ARID1A; EGR4
Function metal ion binding
Related Protein HMOX1; ZNF192; PRICKLE2B; MARCH4; ADAR; POMT1; MT4; NR2F6B; ESRRGB; MLL1
Function protein binding
Related Protein MXD4; ZNF180; KIAA1109; GYPB; STMN2; SHFM1; HTRA3; SNTB2; SH3GL2; S100A2
Function protein heterodimerization activity
Related Protein CYBB; SMAD1; TWIST1; LIMK2; CUL3; KCNK9; TBX18; HIST1H2AF; HEXA; BNIP3
Function transcription corepressor activity
Related Protein DAXX; HSF4; POU1F1; WWTR1; SIAH2; TRIB3; HDAC5; CBX4; NR1H4; E4F1
Function transcription factor activity, sequence-specific DNA binding
Related Protein PRDM2; IRF4; ZNF461; PIP4K2AA; CLOCKA; HSFX1; E2F4; NFE2; HOXA13; ZFP184

Interacting Protein

ZHX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZHX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZHX1.
DNMT3B; ZHX2; ATXN1; NR3C1; PSMD11; BHLHE40; TNFRSF10C; PEX14; PRPF40A; IDH1