znf124
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  • Official Full Name
  • zinc finger protein 124
  • Background
  • This gene encodes a member of the Kruppel-type (C2H2) zinc finger protein family. It has a KRAB-A box at its amino terminus and seven consecutively repeated zinc finger motifs at its carboxy terminus. Expression of this gene is increased after vascular endothelial growth factor (VEGF) stimulation in human leukemia cell lines and its expression inhibits apoptotic cell death induced by irradiation or exposure to etoposide. These attributes suggest that this protein may act as a transcription factor. Alternative splicing results in multiple transcript variants encoding distinct proteins. Additional transcript variants have been described for this gene but their biological validity has not been confirmed. This gene has a pseudogene on chromosome 14.
  • Synonyms
  • ZNF124; zinc finger protein 124; zinc finger protein 124 (HZF 16); HZF 16; HZF16; MGC117046; Zinc finger protein 124 (HZF16); OTTHUMP00000038603; zinc finger protein HZF-16; ZK7; HZF-16
Cat.#:ZNF124-3816HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ZNF124, His-tagged
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Cat.#:ZNF124-144HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human ZNF124 293 Cell Lysate
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Involved Pathway

ZNF124 involved in several pathways and played different roles in them. We selected most pathways ZNF124 participated on our site, such as Gene Expression, Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZNF124 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Gene Expression
FAM36A; ZNF473; TNRC6B; TYW1; COX6C; D1BWG0212E; ZNF41; LSM11; ZNF334; EIF2B1
Generic Transcription Pathway
ARHGEF38; ZNF41; ZNF317; ZNF436; TBX5; SKIA; ZNF446; RARG; ZNF224; ZNF529

Protein Function

ZNF124 has several biochemical functions, for example, DNA binding, metal ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ZNF124 itself. We selected most functions ZNF124 had, and list some proteins which have the same functions with ZNF124. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein PTF1A; GLI1; HIST1H4L; BRPF1; FLYWCH1; Trl; STAT2; DEDD; HIST1H2AB; TCF25
Function metal ion binding
Related Protein ATP2B4; CYP4A14; CYP1C1; CXXC1B; ZNF32; GIT2A; CYP2F2; NPAS2; SCNM1-PS; ZNF143A
Function protein binding
Related Protein HDHD2; PARD3; MFAP4; LRRIQ3; AGT; JAM3B; RFESD; IL13; FKBPL; NOG

Interacting Protein

ZNF124 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZNF124 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZNF124.
FSD2; MEOX2; CCNDBP1; TCF4; KRTAP5-9