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ZP2

  • Official Full Name

    zona pellucida glycoprotein 2 (sperm receptor)

  • Synonyms

    ZP2;zona pellucida glycoprotein 2 (sperm receptor);zona pellucida sperm-binding protein 2;zona pellucida protein A;zona pellucida glycoprotein ZP2;ZPA;Zp-2;

  • Cell & Tissue Lysates
  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Canis lupus familiaris (Dog) (Canis familiaris)
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Macaca radiata (Bonnet macaque)
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Sus scrofa (Pig)
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human ZP2-9193HCL Recombinant Human ZP2 293 Cell Lysate HEK293 N/A
Mouse ZP2-19224M Recombinant Mouse ZP2 Protein Mammalian Cell His
Mouse ZP2-10494M Recombinant Mouse ZP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Zp2-7123M Recombinant Mouse Zp2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse ZP2-10494M-B Recombinant Mouse ZP2 Protein Pre-coupled Magnetic Beads HEK293
Rat ZP2-6715R Recombinant Rat ZP2 Protein Mammalian Cell His
Rat Zp2-7942R Recombinant Rat Zp2 protein, His & T7-tagged E.coli His/T7 Leu353~Pro616 (Accession # O54767)
Rat ZP2-6371R Recombinant Rat ZP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat ZP2-6371R-B Recombinant Rat ZP2 Protein Pre-coupled Magnetic Beads HEK293
Canis lupus familiaris (Dog) (Canis familiaris) RFL18698CF Recombinant Full Length Dog Zona Pellucida Sperm-Binding Protein 2(Zp2) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (39-637)
Cynomolgus Monkey ZP2-1112C Recombinant Cynomolgus ZP2 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey ZP2-855C Recombinant Cynomolgus Monkey ZP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey ZP2-855C-B Recombinant Cynomolgus Monkey ZP2 Protein Pre-coupled Magnetic Beads HEK293
Macaca radiata (Bonnet macaque) RFL20304MF Recombinant Full Length Macaca Radiata Zona Pellucida Sperm-Binding Protein 2(Zp2) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (39-640)
Mus musculus (Mouse) RFL32033MF Recombinant Full Length Mouse Zona Pellucida Sperm-Binding Protein 2(Zp2) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (35-633)
Rattus norvegicus (Rat) RFL26180RF Recombinant Full Length Rat Zona Pellucida Sperm-Binding Protein 2(Zp2) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (25-619)
Sus scrofa (Pig) RFL2690SF Recombinant Full Length Pig Zona Pellucida Sperm-Binding Protein 2(Zp2) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (36-638)
Chicken ZP2-3319C Recombinant Chicken ZP2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • ZP2 Related Articles
  • ZP2 Related Research Area

ZP2 involved in several pathways and played different roles in them. We selected most pathways ZP2 participated on our site, such as Fertilization, Interaction With The Zona Pellucida, Ovarian Infertility Genes, which may be useful for your reference. Also, other proteins which involved in the same pathway with ZP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
FertilizationCATSPERG1;ZP2;TMEM146;ZP3;CATSPERG2;CATSPER1;ADAM20;IZUMO4;IZUMO1
Interaction With The Zona PellucidaADAM2;ZP2;OVGP1;ADAM30;ADAM21;ZP3;ADAM20
Ovarian Infertility GenesSYNE2;NR5A1;DMC1;NRIP1;DAZL;GJA4;INHA;MSH5;ZP3
ReproductionCATSPERG1;OVGP1;CATSPERB;CATSPER1;Acr;TMEM146;CATSPER3;ADAM21;HVCN1

ZP2 has several biochemical functions, for example, acrosin binding, coreceptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ZP2 itself. We selected most functions ZP2 had, and list some proteins which have the same functions with ZP2. You can find most of the proteins on our site.

Function Related Protein
acrosin bindingZP3;ZP2;SERPINA5
coreceptor activityLY96;CD28;RGMA;RGMD;RAMP2;HFE2;PVRL2;PVRL1;ACVR2A

ZP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ZP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ZP2.

SRC; PLCG1

Petit, FM; Serres, C; et al. Moonlighting proteins in sperm-egg interactions. BIOCHEMICAL SOCIETY TRANSACTIONS 42:1740-1743(2014).
Avella, MA; Baibakov, B; et al. A single domain of the ZP2 zona pellucida protein mediates gamete recognition in mice and humans. JOURNAL OF CELL BIOLOGY 205:801-809(2014).
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