ABHD15
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Official Full Name
abhydrolase domain containing 15
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Synonyms
ABHD15; abhydrolase domain containing 15; abhydrolase domain-containing protein 15; ABH15_HUMAN; Abhydrolase domain containing protein 15; hypothetical protein LOC116236; LOC116236; RGD1304598;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | ABHD15-9239H | Recombinant Human ABHD15, His-tagged | E.coli | His | 125-468a.a. |
- Involved Pathway
- Protein Function
- Interacting Protein
- ABHD15 Related Articles
ABHD15 involved in several pathways and played different roles in them. We selected most pathways ABHD15 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with ABHD15 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
ABHD15 has several biochemical functions, for example, hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by ABHD15 itself. We selected most functions ABHD15 had, and list some proteins which have the same functions with ABHD15. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| hydrolase activity | FBP1B;FAHD2B;ADAM25;TMPRSS4A;PPM1LA;ABHD14A;DPEP3;PLCD3A;DDHD1 |
ABHD15 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ABHD15 here. Most of them are supplied by our site. Hope this information will be useful for your research of ABHD15.
rbsB1; thrS2
- Q&As
- Reviews
Q&As (10)
Ask a questionThe expression of ABHD15 is induced during 3T3-L1 adipocyte differentiation and ABHD15 knock down in 3T3-L1 adipocytes resulted in loss of the PDE3B protein.
Using an antibody directed against the whole protein sequence, and the results confirmed in various cell lines that ABHD15 co-immunoprecipitates with PDE3B. Within this complex, ABHD15 likely regulates PDE3B expression and/or protein stability, as its expression is also impaired in the WAT of ABHD15-Knockout mice.
ABHD15 protein was mainly expressed in 3T3-L1 adipocytes and adipose depots, followed by a weak expression in liver and pancreas.ABHD15 was not detected in skeletal muscle (SM) and cardiac muscle (CM)
Because the ABHD15 is mainly expressed in murine adipose tissues and upregulated during in vitro adipogenesi; Additionally, ABHD15 expression is required for adipogenesis since Abhd15-silenced 3T3-L1 cells were unable to increase the expression levels of adipogenic marker genes, leading to reduced lipid accumulation.
Affinity chromatography.
1. Homeostatic process 2. Programmed cell death 3. Lipid metabolic process
Typically, ABHD proteins possess a catalytic triad consisting of a nucleophile (Ser, Cys, or Asp), an acid (aspartate or glutamate), and a conserved histidine residue enabling hydrolase activity, whereas the ABHD15 does not contain a nucleophile.
Prior to lyophilization: 1% BSA and 0.02% NaN3.
Abhd15 is highly expressed in ATs. Further, Abhd15 expression was decreased in white adipose tissue (WAT) of aged and obese mice and in differentiated 3T3-L1 cells upon lipolytic stimulation
ELISA: 1/20000 - 1/80000, WB: 1/200 - 1/1000.
Customer Reviews (4)
Write a reviewI have bought it for twice, nice!
The in-person customer service provide clear expression for both Pre-sale and after-sale!
The purification rsults demonstrtaed clearly! Great.
Prefect product and lovely serivces.
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